Gastrointestinal Stromal Tumor of the Rectum: An Analysis of Seven Cases.

Seung Hyuk Baik; Nam Kyu Kim; Chung Ho Lee; Kang Young Lee; Seung Kook Sohn; Chang Hwan Cho; Hoguen Kim; Hong Ryull Pyo; Sun Young Rha; Hyun Cheol Chung

Abstract Purpose  Gastrointestinal stromal tumors (GISTs) rarely originate in the rectum. We investigated the clinicopathologic characteristics of rectal GISTs. Methods  We analyzed the medical records of seven patients who underwent surgery for GIST of the rectum between 1998 and 2003. Results  There were two men and five women with a median age of 55 years (range, 41–72 years) at the time of diagnosis. The median follow-up period was 23 months (range, 7–75 months). The chief symptoms were hematochezia, constipation, and anal pain. All patients underwent curative resection; in the form of abdominoperineal resection in five patients, transanal excision in one, and Hartmann's operation with prostatectomy in one. The median tumor size was 6.6 cm (range, 1–12 cm). Four patients received adjuvant radiation therapy. Local recurrence developed in two patients; 54 months and 23 months after surgery, respectively. Conclusion  The common symptoms of rectal GIST were the same as those of other rectal tumors. Curative surgical resection should be done, but further studies are necessary to investigate better adjuvant treatment strategies for patients with rectal GISTs

RECTUM tumors; CYSTS (Pathology); MEDICAL informatics; GASTROINTESTINAL diseases; INTESTINAL diseases

Surgery Today, 2007, Vol 37, Issue 6, p455

0941-1291

Academic Journal

10.1007/s00595-006-3424-1