Works matching Treatment of prion diseases

Results: 116

Treatment of Prion Disease with Heterologous Prion Proteins.

Published in:

PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0131993

By:

Skinner, Pamela J.;
Kim, Hyeon O.;
Bryant, Damani;
Kinzel, Nikilyn J.;
Reilly, Cavan;
Priola, Suzette A.;
Ward, Anne E.;
Goodman, Patricia A.;
Olson, Katherine;
Seelig, Davis M.

Publication type:

Article

Pharmacokinetics of quinacrine in the treatment of prion disease.

Published in:

BMC Infectious Diseases, 2004, v. 4, n. 1, p. 53, doi. 10.1186/1471-2334-4-53

By:

Lotus Yung;
Yong Huang;
Lessard, Pierre;
Legname, Giuseppe;
Lin, Emil T.;
Baldwin, Michael;
Prusiner, Stanley B.;
Chongsuk Ryou;
Guglielmo, B. Joseph

Publication type:

Article

Cellulose ether treatment in vivo generates chronic wasting disease prions with reduced protease resistance and delayed disease progression.

Published in:

Journal of Neurochemistry, 2020, v. 152, n. 6, p. 727, doi. 10.1111/jnc.14877

By:

Hannaoui, Samia;
Arifin, Maria Immaculata;
Chang, Sheng Chun;
Yu, Jie;
Gopalakrishnan, Preetha;
Doh‐ura, Katsumi;
Schatzl, Hermann M.;
Gilch, Sabine

Publication type:

Article

Prion diseases and dental treatment: principles and practice of patients with/suspected or at-risk of CJD: Case reports.

Published in:

British Dental Journal, 2003, v. 195, n. 6, p. 319, doi. 10.1038/sj.bdj.4810542

By:

Smith, A.J.;
Sweeney, M.P.;
Bagg, J.

Publication type:

Article

Prions, Parkinson's disease and the search for a new generation of treatments.

Published in:

Progress in Neurology & Psychiatry, 2011, v. 15, n. 6, p. 26, doi. 10.1002/pnp.219

By:

Greener, Mark

Publication type:

Article

2-Aminothiazoles with Improved Pharmacotherapeutic Properties for Treatment of Prion Disease.

Published in:

ChemMedChem, 2013, v. 8, n. 5, p. 847, doi. 10.1002/cmdc.201300007

By:

Li, Zhe;
Silber, B. Michael;
Rao, Satish;
Gever, Joel R.;
Bryant, Clifford;
Gallardo‐Godoy, Alejandra;
Dolghih, Elena;
Widjaja, Kartika;
Elepano, Manuel;
Jacobson, Matthew P.;
Prusiner, Stanley B.;
Renslo, Adam R.

Publication type:

Article

Immunization treatment approaches in Alzheimer’s and prion diseases.

Published in:

Current Neurology & Neuroscience Reports, 2002, v. 2, n. 5, p. 400, doi. 10.1007/s11910-002-0065-7

By:

Wisniewski, Thomas;
Sigurdsson, Einar

Publication type:

Article

P2-380: Identification and characterization of human autoantibodies that may be used for the treatment of prion diseases

Published in:

2008

By:

Du, Yansheng;
Wei, Xing;
He, Yongzheng;
Wei, Gang;
Hampel, Harald;
Dodel, Richard;
Farlow, Martin

Publication type:

Abstract

O4-04-02: Therapeutic effects of gene therapy in the late treatment of prion diseases

Published in:

2008

By:

Verdier, Jean-Michel;
Toupet, Karine;
Compan, Valérie;
Crozet, Carole;
Mestre-Frances, Nadine;
Corbeau, Pierre;
Perrier, Véronique

Publication type:

Abstract

RNAi: a novel strategy for the treatment of prion diseases.

Published in:

Journal of Clinical Investigation, 2006, v. 116, n. 12, p. 3101, doi. 10.1172/JCI30663

By:

Qingzhong Kong

Publication type:

Article

Oral Treatment Targeting the Unfolded Protein Response Prevents Neurodegeneration and Clinical Disease in Prion-Infected Mice.

Published in:

Science Translational Medicine, 2013, v. 5, n. 206, p. 1, doi. 10.1126/scitranslmed.3006767

By:

Moreno, Julie A.;
Halliday, Mark;
Molloy, Colin;
Radford, Helois;
Verity, Nicholas;
Axten, Jeffrey M.;
Ortori, Catharine A.;
Willis, Anne E.;
Fischer, Peter M.;
Barrett, David A.;
Mallucci, Giovanna R.

Publication type:

Article

Prevalence and Treatments of Movement Disorders in Prion Diseases: A Longitudinal Cohort Study.

Published in:

2022

By:

Sequeira, Danielle;
Nihat, Akin;
Mok, Tzehow;
Coysh, Thomas;
Rudge, Peter;
Collinge, John;
Mead, Simon

Publication type:

journal article

Prospects for the Pharmacological Treatment of Human Prion Diseases.

Published in:

CNS Drugs, 1998, v. 10, n. 2, p. 83, doi. 10.2165/00023210-199810020-00001

By:

Adjou, K.T.;
deslys, J-P.;
demaimay, R.;
Seman, M.;
Dormont, D.

Publication type:

Article

Ultraviolet-ozone treatment reduces levels of disease-associated prion protein and prion infectivity.

Published in:: BMC Research Notes, 2009, v. 2, p. 121, doi. 10.1186/1756-0500-2-121
Publication type:: Article

Potential approaches for heterologous prion protein treatment of prion diseases.

Published in:

Prion, 2016, v. 10, n. 1, p. 18, doi. 10.1080/19336896.2015.1123372

By:

Seelig, Davis M.;
Goodman, Patricia A.;
Skinner, Pamela J.

Publication type:

Article

P.185: Quinacrine and its bioavailability in treatment of prion disease.

Published in:

Prion, 2014, v. 8, p. 112

By:

Safarik, Martin;
Mosko, Tibor;
Zawada, Zbigniew;
Dvorakova, Eva;
Holada, Karel;
Sebestik, Jaroslav

Publication type:

Article

Nanomedicine for prion disease treatment.

Published in:

Prion, 2013, v. 7, n. 3, p. 198, doi. 10.4161/pri.24431

By:

McCarthy, James M.;
Appelhans, Dietmar;
Tatzelt, Jörg;
Rogers, Mark S.

Publication type:

Article

Cholesterol and its reciprocal association with prion infection.

Published in:

Cell & Tissue Research, 2023, v. 392, n. 1, p. 235, doi. 10.1007/s00441-022-03669-y

By:

Cashion, Jessica;
Zhang, Wanzhen;
Ali, Tahir;
Gilch, Sabine

Publication type:

Article

Oral administration of repurposed drug targeting Cyp46A1 increases survival times of prion infected mice.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01162-1

By:

Ali, Tahir;
Hannaoui, Samia;
Nemani, Satish;
Tahir, Waqas;
Zemlyankina, Irina;
Cherry, Pearl;
Shim, Su Yeon;
Sim, Valerie;
Schaetzl, Hermann M.;
Gilch, Sabine

Publication type:

Article

Therapeutic interventions ameliorating prion disease.

Published in:

Expert Review of Anti-infective Therapy, 2009, v. 7, n. 1, p. 83, doi. 10.1586/14787210.7.1.83

By:

Brazier, Marcus W.;
Wall, Vanessa A.;
Brazier, Barry W.;
Masters, Colin L.;
Collins, Steven J.

Publication type:

Article

Neural cell engraftment therapy for sporadic Creutzfeldt-Jakob disease restores neuroelectrophysiological parameters in a cerebral organoid model.

Published in:

Stem Cell Research & Therapy, 2023, v. 14, n. 1, p. 1, doi. 10.1186/s13287-023-03591-2

By:

Williams, Katie;
Foliaki, Simote T.;
Race, Brent;
Smith, Anna;
Thomas, Tina;
Groveman, Bradley R.;
Haigh, Cathryn L.

Publication type:

Article

Glimepiride Reduces the Expression of PrPC, Prevents PrPSc Formation and Protects against Prion Mediated Neurotoxicity.

Published in:

PLoS ONE, 2009, v. 4, n. 12, p. 1, doi. 10.1371/journal.pone.0008221

By:

Bate, Clive;
Tayebi, Mourad;
Diomede, Luisa;
Salmona, Mario;
Williams, Alun

Publication type:

Article

Effective Gene Therapy in a Mouse Model of Prion.

Published in:

PLoS ONE, 2008, v. 3, n. 7, p. 1, doi. 10.1371/journal.pone.0002773

By:

Toupet, Karine;
Compan, Valérie;
Crozet, Carole;
Mourton-Gilles, Chantal;
Mestre-Francés, Nadine;
Ibos, Françoise;
Corbeau, Pierre;
Verdier, Jean-Michel;
Perrier, Véronique

Publication type:

Article

Antihypertensive Drug Guanabenz Is Active In Vivo against both Yeast and Mammalian Prions.

Published in:

PLoS ONE, 2008, v. 3, n. 4, p. 1, doi. 10.1371/journal.pone.0001981

By:

Tribouillard-Tanvier, Déborah;
Béringue, Vincent;
Desban, Nathalie;
Gug, Fabienne;
Bach, Stéphane;
Voisset, Cécile;
Galons, Hervé;
Laude, Hubert;
Vilette, Didier;
Blondel, Marc

Publication type:

Article

Antibodies to a Nonconjugated Prion Protein Peptide 95-123 Interfere with PrPSc Propagation in Prion-Infected Cells.

Published in:

Cellular & Molecular Neurobiology, 2007, v. 27, n. 3, p. 271, doi. 10.1007/s10571-006-9108-y

By:

Oboznaya, Maria B.;
Gilch, Sabine;
Titova, Maia A.;
Koroev, Dmitry O.;
Volkova, Tatyana D.;
Volpina, Olga M.;
Schätzl, Hermann M.

Publication type:

Article

Copaxone interferes with the PrPSc–GAG interaction.

Published in:

European Journal of Neurology, 2007, v. 14, n. 8, p. 877, doi. 10.1111/j.1468-1331.2007.01803.x

By:

Engelstein, R.;
Ovadia, H.;
Gabizon, R.

Publication type:

Article

Human prion disease.

Published in:

Clinical & Experimental Neuroimmunology, 2022, v. 13, n. 1, p. 24, doi. 10.1111/cen3.12683

By:

Satoh, Katsuya;
Nakamura, Tatsufumi

Publication type:

Article

Anti-prion drugs do not improve survival in novel knock-in models of inherited prion disease.

Published in:

PLoS Pathogens, 2024, v. 20, n. 4, p. 1, doi. 10.1371/journal.ppat.1012087

By:

Walsh, Daniel J.;
Rees, Judy R.;
Mehra, Surabhi;
Bourkas, Matthew E. C.;
Kaczmarczyk, Lech;
Stuart, Erica;
Jackson, Walker S.;
Watts, Joel C.;
Supattapone, Surachai

Publication type:

Article

Therapeutic effect of peripheral administration of an anti-prion protein antibody on mice infected with prions.

Published in:

Microbiology & Immunology, 2013, v. 57, n. 4, p. 288, doi. 10.1111/1348-0421.12037

By:

Ohsawa, Natsuo;
Song, Chang‐Hyun;
Suzuki, Akio;
Furuoka, Hidefumi;
Hasebe, Rie;
Horiuchi, Motohiro

Publication type:

Article

Identification of a Cardiac Glycoside Exhibiting Favorable Brain Bioavailability and Potency for Reducing Levels of the Cellular Prion Protein.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 23, p. 14823, doi. 10.3390/ijms232314823

By:

Eid, Shehab;
Zerbes, Thomas;
Williams, Declan;
Wang, Xinzhu;
Sackmann, Chris;
Meier, Sammy;
Dulin, Nickolai O.;
Nagorny, Pavel;
Schmitt-Ulms, Gerold

Publication type:

Article

Posteriore kortikale Atrophie.

Published in:

Der Nervenarzt, 2015, v. 86, n. 7, p. 833, doi. 10.1007/s00115-015-4265-1

By:

Ortner, M.;
Kurz, A.

Publication type:

Article

Gene expression and epigenetic markers of prion diseases.

Published in:

Cell & Tissue Research, 2023, v. 392, n. 1, p. 285, doi. 10.1007/s00441-022-03603-2

By:

Viré, Emmanuelle A.;
Mead, Simon

Publication type:

Article

RT-QuIC as ultrasensitive method for prion detection.

Published in:

Cell & Tissue Research, 2023, v. 392, n. 1, p. 295, doi. 10.1007/s00441-021-03568-8

By:

Atarashi, Ryuichiro

Publication type:

Article

Unsuccessful intraventricular pentosan polysulphate treatment of variant Creutzfeldt-Jakob disease.

Published in:

Acta Neurochirurgica, 2006, v. 148, n. 6, p. 677, doi. 10.1007/s00701-006-0772-y

By:

Whittle, I. R.;
Knight, R. S. G.;
Will, R. G.

Publication type:

Article

Evaluation of a New Criterion for Detecting Prion Disease With Diffusion Magnetic Resonance Imaging.

Published in:

JAMA Neurology, 2020, v. 77, n. 9, p. 1141, doi. 10.1001/jamaneurol.2020.1319

By:

Bizzi, Alberto;
Pascuzzo, Riccardo;
Blevins, Janis;
Grisoli, Marina;
Lodi, Raffaele;
Moscatelli, Marco E. M.;
Castelli, Gianmarco;
Cohen, Mark L.;
Schonberger, Lawrence B.;
Foutz, Aaron;
Safar, Jiri G.;
Appleby, Brian S.;
Gambetti, Pierluigi

Publication type:

Article

Molecular pathogenesis of prion diseases.

Published in:

European Archives of Psychiatry & Clinical Neuroscience, 1999, v. 249, p. S56, doi. 10.1007/PL00014175

By:

Kretzschmar, Hans A.

Publication type:

Article

Peptide aptamer targeting Aβ–PrP–Fyn axis reduces Alzheimer's disease pathologies in 5XFAD transgenic mouse model.

Published in:

Cellular & Molecular Life Sciences, 2023, v. 80, n. 6, p. 1, doi. 10.1007/s00018-023-04785-w

By:

Ali, Tahir;
Klein, Antonia N.;
Vu, Alex;
Arifin, Maria I.;
Hannaoui, Samia;
Gilch, Sabine

Publication type:

Article

Anti-PrP antibodies block PrPSc replication in prion-infected cell cultures by accelerating PrPC degradation.

Published in:

Journal of Neurochemistry, 2004, v. 89, n. 2, p. 454, doi. 10.1111/j.1471-4159.2004.02356.x

By:

Perrier, Véronique;
Solassol, Jérôme;
Crozet, Carole;
Frobert, Yveline;
Mourton-Gilles, Chantal;
Grassi, Jacques;
Lehmann, Sylvain

Publication type:

Article

Lithium as a disease-modifying agent for prion diseases.

Published in:

Translational Psychiatry, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41398-018-0209-4

By:

Relaño-Ginés, A.;
Lehmann, S.;
Brillaud, E.;
Belondrade, M.;
Casanova, D.;
Hamela, C.;
Vincent, C.;
Poupeau, S.;
Sarniguet, J.;
Alvarez, T.;
Arnaud, J. D.;
Maurel, J. C.;
Crozet, C.

Publication type:

Article

Selective activation by photodynamic action of cholecystokinin receptor in the freshly isolated rat pancreatic acini.

Published in:

British Journal of Pharmacology, 2003, v. 139, n. 4, p. 872, doi. 10.1038/sj.bjp.0705295

By:

Yu Ping An, Stephen J.;
Rui Xiao, Stephen J.;
Hong Cui, Stephen J.;
Zong Jie Cui, Stephen J.

Publication type:

Article

Aptamer Applications in Neuroscience.

Published in:

Pharmaceuticals (14248247), 2021, v. 14, n. 12, p. 1260, doi. 10.3390/ph14121260

By:

Ozturk, Meric;
Nilsen-Hamilton, Marit;
Ilgu, Muslum

Publication type:

Article

Novel dominant-negative prion protein mutants identified from a randomized library.

Published in:

PEDS: Protein Engineering, Design & Selection, 2008, v. 21, n. 10, p. 623, doi. 10.1093/protein/gzn042

By:

David Ott;
Cornelia Taraborrelli;
Adriano Aguzzi

Publication type:

Article

The N-Terminal, Polybasic Region of PrPC Dictates the Efficiency of Prion Propagation by Binding to PrPSc.

Published in:

Journal of Neuroscience, 2012, v. 32, n. 26, p. 8817, doi. 10.1523/JNEUROSCI.1103-12.2012

By:

Turnbaugh, Jessie A.;
Unterberger, Ursula;
Saá, Paula;
Massignan, Tania;
Fluharty, Brian R.;
Bowman, Frederick P.;
Miller, Michael B.;
Supattapone, Surachai;
Biasini, Emiliano;
Harris, David A.

Publication type:

Article

Fatal Prion Disease in a Mouse Model of Genetic E200K Creutzfeldt-Jakob Disease.

Published in:

PLoS Pathogens, 2011, v. 7, n. 11, p. 1, doi. 10.1371/journal.ppat.1002350

By:

Friedman-Levi, Yael;
Meiner, Zeev;
Canello, Tamar;
Frid, Kati;
Kovacs, Gabor G.;
Budka, Herbert;
Avrahami, Dana;
Gabizon, Ruth

Publication type:

Article

Electrochemiluminescence of Acridines.

Published in:

Electroanalysis, 2016, v. 28, n. 11, p. 2672, doi. 10.1002/elan.201600209

By:

Majeed, Saadat;
Gao, Wenyue;
Zholudov, Yuriy;
Muzyka, Kateryna;
Xu, Guobao

Publication type:

Article

Update on a brain-penetrant cardiac glycoside that can lower cellular prion protein levels in human and guinea pig paradigms.

Published in:

PLoS ONE, 2024, v. 19, n. 9, p. 1, doi. 10.1371/journal.pone.0308821

By:

Eid, Shehab;
Zhao, Wenda;
Williams, Declan;
Nasser, Zahra;
Griffin, Jennifer;
Nagorny, Pavel;
Schmitt-Ulms, Gerold

Publication type:

Article

Delayed synaptic degeneration in the CNS of Wlds mice after cortical lesion.

Published in:

2006

By:

Gillingwater TH;
Ingham CA;
Parry KE;
Wright AK;
Haley JE;
Wishart TM;
Arbuthnott GW;
Ribchester RR;
Gillingwater, Thomas H;
Ingham, Cali A;
Parry, Katherine E;
Wright, Ann K;
Haley, Jane E;
Wishart, Thomas M;
Arbuthnott, Gordon W;
Ribchester, Richard R

Publication type:

journal article

Delayed synaptic degeneration in the CNS of Wlds mice after cortical lesion.

Published in:

Brain: A Journal of Neurology, 2006, v. 129, n. 6, p. 1546

By:

Thomas H. Gillingwater;
Cali A. Ingham

Publication type:

Article

Cellular models for discovering prion disease therapeutics: Progress and challenges.

Published in:

Journal of Neurochemistry, 2020, v. 153, n. 2, p. 150, doi. 10.1111/jnc.14956

By:

Krance, Saffire H.;
Luke, Russell;
Shenouda, Marc;
Israwi, Ahmad R.;
Colpitts, Sarah J.;
Darwish, Lina;
Strauss, Maximilian;
Watts, Joel C.

Publication type:

Article

Perspectives on CRISPR Genome Editing to Prevent Prion Diseases in High-Risk Individuals.

Published in:

Biomedicines, 2024, v. 12, n. 8, p. 1725, doi. 10.3390/biomedicines12081725

By:

Medd, Milan M.;
Cao, Qi

Publication type:

Article