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- Title
Gradient compression garments protect against orthostatic intolerance during recovery from bed rest.
- Authors
Stenger, Michael; Lee, Stuart; Ribeiro, L.; Phillips, Tiffany; Ploutz-Snyder, Robert; Willig, Michael; Westby, Christian; Platts, Steven
- Abstract
Introduction: Abdomen-high, lower body graded compression garments (GCGs) may represent the next-generation of orthostatic intolerance protection with applications for exploration missions and commercial space flight. Purpose: To evaluate the efficacy of the GCG to prevent orthostatic intolerance after a 14-day 6° head-down tilt bed rest (BR) and to determine whether wearing thigh-high compression garments impairs recovery from BR. Methods: Sixteen (12 M, 4 F) subjects participated in a 15-min 80° head-up tilt test 5 day before BR (BR-5), on the last morning of BR (BR 0), and on day 1 (BR 1) and 3 after BR (BR 3). No subjects wore the GCG on BR-5, and all subjects wore the GCG during testing on BR 0. Control subjects ( n = 8) wore the GCG only through testing on BR 0. Treatment subjects ( n = 8) wore the GCG on BR 0 and thigh-high garments on BR 1 and BR 2. Results: No subjects were presyncopal during tilt on BR 0 while wearing the GCG. Despite lower plasma volume index (BR-5: 1.52 ± 0.06, BR 0: 1.32 ± 0.05 l/m), the tilt-induced increase in heart rate (ΔHR, 17 ± 2 bpm) and decrease in stroke volume (ΔSV, −28 ± 3 ml) on BR 0 were less than on BR-5 (24 ± 2 bpm, −43 ± 4 ml). On BR 1 ΔHR in the control group (33 ± 4 bpm) was higher than in the treatment group (23 ± 2 bpm) but there were no group differences on BR 3. Conclusions: Wearing the GCG prevented the orthostatic intolerance that is normally present after BR. Thigh-high garments provided protection after BR, and wearing these garments did not impair recovery.
- Subjects
PHYSIOLOGICAL effects of space travel; ORTHOSTATIC hypotension; SYNCOPE; PROTECTIVE clothing; PHYSIOLOGICAL aspects of clothing & dress
- Publication
European Journal of Applied Physiology, 2014, Vol 114, Issue 3, p597
- ISSN
1439-6319
- Publication type
Academic Journal
- DOI
10.1007/s00421-013-2787-4