Works matching DE "DNA topoisomerase I"
Results: 1199
Topoisomerase I poisoning results in PARP-mediated replication fork reversal.
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- Nature Structural & Molecular Biology, 2012, v. 19, n. 4, p. 417, doi. 10.1038/nsmb.2258
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- Article
Cytotoxicity and DNA Topoisomerase Inhibitory Activity of Benz[f]indole-4,9-dione Analogs.
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- Bioscience, Biotechnology & Biochemistry, 2003, v. 67, n. 9, p. 1944, doi. 10.1271/bbb.67.1944
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- Article
Inactivation of Trypanosoma cruzi and Crithidia fasciculata topoisomerase I by Fenton systems.
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- Redox Report, 2003, v. 8, n. 6, p. 357, doi. 10.1179/135100003225003366
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- Article
Two‐Phase Electrosynthesis of Dihydroxycoumestans: Discovery of a New Scaffold for Topoisomerase I Poison.
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- Chemistry - A European Journal, 2024, v. 30, n. 39, p. 1, doi. 10.1002/chem.202401400
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- Article
Direct Growth Control of Antibiotic‐Resistant Bacteria Using Visible‐Light‐Responsive Novel Photoswitchable Antibiotics.
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- Chemistry - A European Journal, 2024, v. 30, n. 15, p. 1, doi. 10.1002/chem.202303685
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- Article
2D Core/Shell‐Structured Mesoporous Silicene@Silica for Targeted and Synergistic NIR‐II‐Induced Photothermal Ablation and Hypoxia‐Activated Chemotherapy of Tumors.
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- Advanced Functional Materials, 2021, v. 31, n. 24, p. 1, doi. 10.1002/adfm.202102043
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- Article
Human topoisomerase I poisoning: docking protoberberines into a structure-based binding site model.
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- Journal of Computer-Aided Molecular Design, 2004, v. 18, n. 12, p. 785, doi. 10.1007/s10822-004-7878-1
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- Article
Progression-free survival and overall survival of patients with clear cell carcinoma of the ovary treated with paclitaxel-carboplatin or irinotecan-cisplatin: retrospective analysis.
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- International Journal of Clinical Oncology, 2007, v. 12, n. 4, p. 256, doi. 10.1007/s10147-007-0670-1
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Evolutionary History of TOPIIA Topoisomerases in Animals.
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- Journal of Molecular Evolution, 2022, v. 90, n. 2, p. 149, doi. 10.1007/s00239-022-10048-2
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- Article
Molecular Evolution of DNA Topoisomerase III Beta (TOP3B) in Metazoa.
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- Journal of Molecular Evolution, 2021, v. 89, n. 6, p. 384, doi. 10.1007/s00239-021-10011-7
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- Article
Evolution of the Relaxin/Insulin-like Gene Family in Placental Mammals: Implications for Its Early Evolution.
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- Journal of Molecular Evolution, 2011, v. 72, n. 1, p. 72, doi. 10.1007/s00239-010-9403-6
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- Article
Avoidance of ribonucleotide-induced mutations by RNase H2 and Srs2-Exo1 mechanisms.
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- Nature, 2014, v. 511, n. 7508, p. 251, doi. 10.1038/nature13292
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- Article
Chromosome length influences replication-induced topological stress.
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- Nature, 2011, v. 471, n. 7338, p. 392, doi. 10.1038/nature09791
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- Article
Mechanisms of Secondary Leukemia Development Caused by Treatment with DNA Topoisomerase Inhibitors.
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- Biochemistry (00062979), 2023, v. 88, n. 7, p. 892, doi. 10.1134/S0006297923070040
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- Article
2-Amino-Pyrrole-Carboxylate Attenuates Homology-Mediated DNA Repair and Sensitizes Cancer Cells to Doxorubicin.
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- Biochemistry (00062979), 2022, v. 87, n. 5, p. 391, doi. 10.1134/S0006297922050017
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Valproic acid as a potent substance for increasing efficacy of topoisomerase I inhibitors.
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- Turkish Journal of Cancer, 2009, v. 39, n. 3, p. 104
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- Article
The Expression of Bcl-XL, Bcl-XS and p27Kip1 in Topotecan-Induced Apoptosis in Hepatoblastoma HepG2 Cell Line.
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- Cancer Investigation, 2008, v. 26, n. 5, p. 456, doi. 10.1080/07357900701683968
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AN UPDATE ON WEEKLY TOPOTECAN (HYCAMTIN®) IN SOLID TUMORS.
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- 2004
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- Abstract
RUBITECAN, AN ORAL TOPOISOMERASE I INHIBITOR, FOR THE TREATMENT OF PANCREATIC CANCER.
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- 2004
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- Abstract
A phase II study of topotecan in non-Hodgkin's lymphoma: an Ohio State University phase II research consortium study.
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- 2002
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- journal article
The combined effects of proteasome inhibitor bortezomib with topoisomerase I and II inhibitors on topoisomerase enzymes.
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- Turkish Journal of Medical Sciences, 2016, v. 46, n. 6, p. 1882, doi. 10.3906/sag-1511-184
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- Article
Partial Purification of Topoisomerase I from Mycobacterium phlei.
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- Turkish Journal of Medical Sciences, 2008, v. 38, n. 3, p. 251
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- Article
A game of musical chairs: Pro- and anti-resection factors compete for TOP BP1 binding after DNA damage.
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- Journal of Cell Biology, 2017, v. 216, n. 3, p. 535, doi. 10.1083/jcb.201701038
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- Article
PARP-1 ensures regulation of replication fork progression by homologous recombination on damaged DNA.
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- Journal of Cell Biology, 2008, v. 183, n. 7, p. 1203, doi. 10.1083/jcb.200806068
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- Article
Organization of chromatin and histone modifications at a transcription site.
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- Journal of Cell Biology, 2007, v. 177, n. 6, p. 957, doi. 10.1083/jcb.200703157
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- Article
Characterisation and antiproliferative activity of irinotecan and sulphonatocalixarene inclusion complex.
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- Supramolecular Chemistry, 2011, v. 23, n. 6, p. 441, doi. 10.1080/10610278.2010.544736
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- Article
Evaluation of topoisomerase I and II status in human breast cancer cell lines.
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- Oncolog-Hematolog, 2018, n. 43, p. 54
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- Article
Synthesis of Novel N -Heterocyclic Carbene-Ruthenium (II) Complexes, "Precious" Tools with Antibacterial, Anticancer and Antioxidant Properties.
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- Antibiotics (2079-6382), 2023, v. 12, n. 4, p. 693, doi. 10.3390/antibiotics12040693
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- Article
Seconeolitsine, the Novel Inhibitor of DNA Topoisomerase I, Protects against Invasive Pneumococcal Disease Caused by Fluoroquinolone-Resistant Strains.
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- Antibiotics (2079-6382), 2021, v. 10, n. 5, p. 573, doi. 10.3390/antibiotics10050573
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- Article
Topoisomerase I prevents transcription-replication conflicts at transcription termination sites.
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- Molecular & Cellular Oncology, 2021, v. 8, n. 1, p. 1, doi. 10.1080/23723556.2020.1843951
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- Article
Curcumin protects against testis-specific side effects of irinotecan.
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- European Review for Medical & Pharmacological Sciences, 2021, v. 25, n. 23, p. 7440
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- Article
Biochemical Basis of the Antimicrobial Activity of Quinazolinone Derivatives in the Light of Insights into the Features of the Chemical Structure and Ways of Binding to Target Molecules. A Review.
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- Doklady Chemistry, 2023, v. 510, n. 1, p. 107, doi. 10.1134/S0012500823600463
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- Article
Catalytic selectivity and evolution of cytochrome P450 enzymes involved in monoterpene indole alkaloids biosynthesis.
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- Physiologia Plantarum, 2024, v. 176, n. 5, p. 1, doi. 10.1111/ppl.14515
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- Article
In Silico Study of Camptothecin-Based Pro-Drugs Binding to Human Carboxylesterase 2.
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- Biomolecules (2218-273X), 2024, v. 14, n. 2, p. 153, doi. 10.3390/biom14020153
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- Article
Predictive Modeling of Proteins Encoded by a Plant Virus Sheds a New Light on Their Structure and Inherent Multifunctionality.
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- Biomolecules (2218-273X), 2024, v. 14, n. 1, p. 62, doi. 10.3390/biom14010062
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- Article
Interaction of the Emerging Mycotoxins Beauvericin, Cyclopiazonic Acid, and Sterigmatocystin with Human Serum Albumin.
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- Biomolecules (2218-273X), 2022, v. 12, n. 8, p. 1106, doi. 10.3390/biom12081106
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- Article
Rescuing and utilizing anticancer Nothapodytes species: Integrated studies from plant resources to natural medicines.
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- Clinical & Translational Medicine, 2024, v. 14, n. 12, p. 1, doi. 10.1002/ctm2.70110
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- Article
Merging perspectives: genotype‐directed molecular therapy for hereditary diffuse gastric cancer (HDGC) and E‐cadherin–EGFR crosstalk.
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- Clinical & Translational Medicine, 2018, v. 7, n. 1, p. 1, doi. 10.1186/s40169-018-0184-7
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- Article
DNA topoisomerases as targets for anticancer drugs.
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- Journal of Clinical Pharmacy & Therapeutics, 2001, v. 26, n. 6, p. 405, doi. 10.1046/j.1365-2710.2001.00368.x
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- Article
A recombinant topoisomerase I ELISA: screening for IgG, IgM and IgA anti-topo I autoantibodies in human sera.
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- Clinical & Experimental Immunology, 1992, v. 89, n. 3, p. 456
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- Article
Elevations of DNA Topoisomerase I in Invasive Carcinoma of the Breast.
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- Breast Journal, 2001, v. 7, n. 3, p. 176, doi. 10.1046/j.1524-4741.2001.007003176.x
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- Article
Anti-topoisomerase-I antibodies in systemic lupus erythematosus and potential association with the presence of anti-dsDNA antibodies.
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- Lupus, 2017, v. 26, n. 10, p. 1121, doi. 10.1177/0961203317696592
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- Article
Retinal Vascular Features Associated with Risk of Branch Retinal Vein Occlusion.
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- Current Eye Research, 2013, v. 38, n. 9, p. 989, doi. 10.3109/02713683.2013.798420
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- Article
Colorectal Cancer: Disease Management Considerations.
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- Drugs, 2001, v. 61, n. 12, p. 1751, doi. 10.2165/00003495-200161120-00006
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- Article
Topotecan: A Review of its Potential in Advanced Ovarian Cancer.
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- Drugs, 1998, v. 56, n. 4, p. 709
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- Article
[fam‐] trastuzumab deruxtecan, antitumor activity is dependent on HER2 expression level rather than on HER2 amplification.
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- International Journal of Cancer, 2019, v. 145, n. 12, p. 3414, doi. 10.1002/ijc.32408
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- Article
Targeting neddylation sensitizes colorectal cancer to topoisomerase I inhibitors by inactivating the DCAF13-CRL4 ubiquitin ligase complex.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39374-9
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- Article
Efflux pump gene amplifications bypass necessity of multiple target mutations for resistance against dual-targeting antibiotic.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38507-4
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- Article
Replication-associated formation and repair of human topoisomerase IIIα cleavage complexes.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37498-6
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- Article
Structural and biochemical basis for DNA and RNA catalysis by human Topoisomerase 3β.
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- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32221-3
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- Article