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- Title
Initiation of ovarian stimulation independent of the menstrual cycle: a case-control study.
- Authors
Buendgen, Nana Kristin; Schultze-Mosgau, Askan; Cordes, Tim; Diedrich, Klaus; Griesinger, Georg
- Abstract
In the GnRH-antagonist protocol, ovarian stimulation with gonadotropins typically commences on cycle day 2 or 3. Initiation of ovarian stimulation with a spontaneously occurring menstruation, however, poses significant organizational challenges for treatment centres and patients alike. It has previously been demonstrated in the context of fertility preservation that initiation of stimulation in the luteal phase is feasible in terms of retrieval of mature oocytes for cryopreservation. Herein, we report the extension of this concept to a routine IVF setting with the aim of establishing an ovarian stimulation protocol, which can be utilized independent of menstruation. Because of asynchrony of endometrium and embryo in such a setting, all fertilized oocytes have to be cryopreserved for a later transfer.
- Publication
Archives of gynecology and obstetrics, 2013, Vol 288, Issue 4, p901
- ISSN
1432-0711
- Publication type
Journal Article
- DOI
10.1007/s00404-013-2794-z