Works matching DE "DRUG target"

Results: 5000

The Evolution of Anti-CD20 Treatment for Multiple Sclerosis: Optimization of Antibody Characteristics and Function.

Published in:

CNS Drugs, 2025, v. 39, n. 6, p. 545, doi. 10.1007/s40263-025-01182-8

By:

Cree, Bruce A. C.;
Berger, Joseph R.;
Greenberg, Benjamin

Publication type:

Article

Sirt6 deficiency promotes senescence and age-associated intervertebral disc degeneration in mice.

Published in:

Bone Research, 2025, v. 13, n. 1, p. 1, doi. 10.1038/s41413-025-00422-3

By:

Ramteke, Pranay;
Watson, Bahiyah;
Toci, Mallory;
Tran, Victoria A.;
Johnston, Shira;
Tsingas, Maria;
Barve, Ruteja A.;
Mitra, Ramkrishna;
Loeser, Richard F.;
Collins, John A.;
Risbud, Makarand V.

Publication type:

Article

Molecular landscape of atherosclerotic plaque progression: insights from proteomics, single-cell transcriptomics and genomics.

Published in:

BMC Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12916-025-04058-2

By:

Wang, Chaonan;
Feng, Yuyao;
Liu, Xiaoyan;
Sun, Haidan;
Guo, Zhengguang;
Shao, Jiang;
Li, Kang;
Chen, Junye;
Shu, Keqiang;
Kong, Deqiang;
Wang, Jiaxian;
Li, Yiran;
Lei, Xiangling;
Li, Chen;
Liu, Bao;
Sun, Wei;
Lai, Zhichao

Publication type:

Article

Expression patterns, prognostic significance, and immune correlations of the TNFAIP8 family in acute myeloid leukemia: a comprehensive bioinformatics analysis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02511-5

By:

Zhang, Xuezhong;
Qu, Min;
Bi, Lei;
Wang, Xiaolei;
Liu, Tonggang

Publication type:

Article

Nicotine‐driven enhancement of tumor malignancy in triple‐negative breast cancer via additive regulation of CHRNA9 and IGF1R.

Published in:

Journal of Pathology, 2025, v. 266, n. 2, p. 230, doi. 10.1002/path.6423

By:

Kuo, Yung‐Che;
Chen, Chi‐Long;
Lee, Kha‐Liang;
Wang, Hsiao‐Feng;
Drew, Victor James;
Lan, Pei‐Chi;
Ho, Yuan‐Soon;
Huang, Yen‐Hua

Publication type:

Article

Péter Ábrányi‐Balogh.

Published in:

Angewandte Chemie, 2025, v. 137, n. 19, p. 1, doi. 10.1002/ange.202505411

By:

Ábrányi‐Balogh, Péter

Publication type:

Article

Expanding the SLURP1 disease spectrum: from Mal de Meleda to palmoplantar keratoderma/progressive symmetric erythrokeratoderma.

Published in:

British Journal of Dermatology, 2025, v. 192, n. 5, p. 793, doi. 10.1093/bjd/ljaf059

By:

Takeichi, Takuya;
Hsu, Chao-Kai

Publication type:

Article

New Investigator Free Papers.

Published in:: International Journal of Rheumatic Diseases, 2025, v. 28, p. 1, doi. 10.1111/1756-185X.70263
Publication type:: Article

The molecular impact of miR-326 in acute lymphoblastic leukemia and its cross talk with P53.

Published in:

Annals of Hematology, 2025, v. 104, n. 4, p. 2417, doi. 10.1007/s00277-024-06181-1

By:

Shafieizadegan, Saba;
Aberuyi, Narges;
Rahgozar, Soheila

Publication type:

Article

Exploring secondary extramedullary myeloma disease: a five-predictor scoring system with spotlight on double-hit cytogenetics.

Published in:

BMC Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12916-025-04086-y

By:

Tao, Yi;
Jin, Shi-Wei;
Wang, Zhe;
Pan, Mengmeng;
Ouyang, Wanyan;
Xu, Jie;
Liu, Yuanfang;
Wang, Yan;
Zhang, Weiping;
Li, Jian;
Mi, Jian-Qing

Publication type:

Article

Oligodendroglia vulnerability in the human dorsal striatum in Parkinson's disease.

Published in:

Acta Neuropathologica, 2025, v. 149, n. 1, p. 1, doi. 10.1007/s00401-025-02884-5

By:

Barba-Reyes, Juan M.;
Harder, Lisbeth;
Marco Salas, Sergio;
Jaisa-aad, Methasit;
Muñoz-Castro, Clara;
Garma, Leonardo D.;
Rafati, Nima;
Nilsson, Mats;
Hyman, Bradley T.;
Serrano-Pozo, Alberto;
Muñoz-Manchado, Ana B.

Publication type:

Article

Identification and validation of susceptibility modules and hub genes of adrenocortical carcinoma through WGCNA and machine learning.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02396-4

By:

Yang, Yaoming;
Wang, Xinbao;
Wu, Liuqing;
Zhao, Shihua;
Chen, Ran;
Yu, Guoyong

Publication type:

Article

Integrating analysis of multi-omics summary data identifies novel plasma protein biomarkers and drug targets for bladder cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02476-5

By:

Cao, Jinlong;
Chen, Siyu;
Wang, Jirong;
Fan, Xinpeng;
Liu, Shanhui;
Shan, Jiaqi;
Li, Xiaoran;
Yang, Li

Publication type:

Article

Drug repurposing a compelling cancer strategy with bottomless opportunities: Recent advancements in computational methods and molecular mechanisms.

Published in:

Indian Journal of Pharmacology, 2023, v. 55, n. 5, p. 322, doi. 10.4103/ijp.ijp_626_22

By:

Dash, Rasmita;
Yadav, Madhulika;
Biswal, Jyotirmaya;
Samanta, Shrabani;
Sharma, Tripti;
Mohapatra, Sujata

Publication type:

Article

Students' knowledge and views on pharmacogenomic education in the medical curriculum.

Published in:

Indian Journal of Pharmacology, 2021, v. 53, n. 1, p. 19, doi. 10.4103/ijp.IJP_495_19

By:

Agrawal, Manju;
Kirtania, Lopamudra;
Jha, Anuja;
Hishikar, Rajesh

Publication type:

Article

Drug targets for corona virus: A systematic review.

Published in:

Indian Journal of Pharmacology, 2020, v. 52, n. 1, p. 56, doi. 10.4103/ijp.IJP_115_20

By:

Prajapat#, Manisha;
Sarma#, Phulen;
Shekhar#, Nishant;
Avti, Pramod;
Sinha, Shweta;
Kaur, Hardeep;
Kumar, Subodh;
Bhattacharyya, Anusuya;
Kumar, Harish;
Bansal, Seema;
Medhi, Bikash

Publication type:

Article

Sexually transmitted diseases putative drug target database: A comprehensive database of putative drug targets of pathogens identified by comparative genomics.

Published in:

Indian Journal of Pharmacology, 2013, v. 45, n. 5, p. 434, doi. 10.4103/0253-7613.117719

By:

Malipatil, Vijayakumari;
Madagi, Shivkumar;
Bhattacharjee, Biplab

Publication type:

Article

Ghrelin: A potential drug target for obesity.

Published in:

2005

By:

Madan, A.K.;
Hore, S.K.;
Korde, J.P.;
Singh, R.;
Rastogi, S.K.

Publication type:

Report

The Emerging Therapeutic Targets for Scar Management: Genetic and Epigenetic Landscapes.

Published in:

Skin Pharmacology & Physiology, 2022, v. 35, n. 5, p. 247, doi. 10.1159/000524990

By:

Amjadian, Sara;
Moradi, Sharif;
Mohammadi, Parvaneh

Publication type:

Article

Transdisciplinary research and clinical priorities for better health.

Published in:

2021

By:

Fontana, Luigi;
Fasano, Alessio;
Chong, Yap Seng;
Vineis, Paolo;
Willett, Walter C.

Publication type:

journal article

The Role of the Cerebellum in Drug Reward: A Review.

Published in:

Journal of Integrative Neuroscience, 2023, v. 22, n. 6, p. 1, doi. 10.31083/j.jin2206147

By:

Yong-bo Wang;
Yan Lan

Publication type:

Article

PfgPDI: Pocket feature-enabled graph neural network for protein-drug interaction prediction.

Published in:

Journal of Bioinformatics & Computational Biology, 2024, v. 22, n. 2, p. 1, doi. 10.1142/S0219720024500045

By:

Zhang, Yiqian;
Zhou, Changjian

Publication type:

Article

Target-based drug discovery for -globin disorders: drug target prediction using quantitative modeling with hybrid functional Petri nets.

Published in:

Journal of Bioinformatics & Computational Biology, 2016, v. 14, n. 5, p. -1, doi. 10.1142/S0219720016500268

By:

Mehraei, Mani;
Bashirov, Rza;
Tüzmen, Şükrü

Publication type:

Article

DRUG TARGET PRIORITIZATION IN PLASMODIUM FALCIPARUM THROUGH METABOLIC NETWORK ANALYSIS, AND INHIBITOR DESIGNING USING VIRTUAL SCREENING AND DOCKING APPROACH.

Published in:

Journal of Bioinformatics & Computational Biology, 2013, v. 11, n. 4, p. -1, doi. 10.1142/S0219720013500030

By:

YADAV, MANOJ KUMAR;
PANDEY, SAURABH KUMAR;
SWATI, D.

Publication type:

Article

ERRATA.

Published in:: Journal of Bioinformatics & Computational Biology, 2004, v. 1, n. 4, p. 751, doi. 10.1142/S0219720004000429
Publication type:: Article

Cyclization by Intramolecular Suzuki‐Miyaura Cross‐Coupling–A Review.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 1, p. 1, doi. 10.1002/chem.202402664

By:

Caso, Carolina;
Altmann, Karl‐Heinz

Publication type:

Article

Target Fisher: A Consensus Structure‐Based Target Prediction Tool, and its Application in the Discovery of Selective MAO‐B Inhibitors.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 1, p. 1, doi. 10.1002/chem.202401838

By:

Fernández, Julián F.;
Martinez Heredia, Leandro;
Caracciolo, Fernando;
Esses, Daniel;
Suarez, Rodrigo;
Siless, Gaston;
Perez, Concepcion;
Isabel Rodríguez‐Franco, María;
Fernández, Lucía R.;
Palermo, Jorge A.;
Lavecchia, Martín

Publication type:

Article

Front Cover: Secondary Sphere Lewis Acid Activated Heme Superoxo Adducts Mimic Crucial Non‐Covalent Interactions in IDO/TDO Heme Dioxygenases (Chem. Eur. J. 68/2024).

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 68, p. 1, doi. 10.1002/chem.202486801

By:

Tolbert, Garrett B.;
Jayawardana, Samith B.;
Lee, Yuri;
Sun, Junqi;
Qu, Fengrui;
Whitt, Logan M.;
Shafaat, Hannah S.;
Wijeratne, Gayan B.

Publication type:

Article

Non‐Medical Applications of Inorganic Medicines. A Switch Based on Mechanistic Knowledge.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 60, p. 1, doi. 10.1002/chem.202402647

By:

Cirri, Damiano;
Di Leo, Riccardo;
Chiaverini, Lorenzo;
Tolbatov, Iogann;
Marrone, Alessandro;
Messori, Luigi;
Pratesi, Alessandro;
La Mendola, Diego;
Marzo, Tiziano

Publication type:

Article

Structure‐Based Design of Ultrapotent Tricyclic Ligands for FK506‐Binding Proteins.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 45, p. 1, doi. 10.1002/chem.202401405

By:

Krajczy, Patryk;
Meyners, Christian;
Repity, Maximilian L.;
Hausch, Felix

Publication type:

Article

Identification of Potential Drug Targets of Calix[4]arene by Reverse Docking.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 42, p. 1, doi. 10.1002/chem.202400871

By:

Giugliano, Giulia;
Gajo, Margherita;
Marforio, Tainah Dorina;
Zerbetto, Francesco;
Mattioli, Edoardo Jun;
Calvaresi, Matteo

Publication type:

Article

Conformational and Electronic Variations in 1,2‐ and 1,5a‐Cyclophellitols and their Impact on Retaining α‐Glucosidase Inhibition.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 31, p. 1, doi. 10.1002/chem.202400723

By:

Ofman, Tim P.;
Heming, Jurriaan J. A.;
Nin‐Hill, Alba;
Küllmer, Florian;
Moran, Elisha;
Bennett, Megan;
Steneker, Roy;
Klein, Anne‐Mei;
Ruijgrok, Gijs;
Kok, Ken;
Armstrong, Zach W. B.;
Aerts, Johannes M. F. G.;
van der Marel, Gijsbert A.;
Rovira, Carme;
Davies, Gideon J.;
Artola, Marta;
Codée, Jeroen D. C.;
Overkleeft, Herman S.

Publication type:

Article

Development of Receptor for Advanced Glycation End Products (RAGE) ligands through target directed dynamic combinatorial chemistry: a novel class of possible antagonists.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 20, p. 1, doi. 10.1002/chem.202303255

By:

Dascalu, Anca‐Elena;
Furman, Christophe;
Landrieu, Isabelle;
Cantrelle, François‐Xavier;
Mortelecque, Justine;
Grolaux, Gaëlle;
Gillery, Philippe;
Tessier, Frédéric;
Lipka, Emmanuelle;
Billamboz, Muriel;
Boulanger, Eric;
Ghinet, Alina

Publication type:

Article

Computational Design of α‐Conotoxins to Target Specific Nicotinic Acetylcholine Receptor Subtypes.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 7, p. 1, doi. 10.1002/chem.202302909

By:

Wu, Xiaosa;
Hone, Arik J.;
Huang, Yen‐Hua;
Clark, Richard J.;
McIntosh, J. Michael;
Kaas, Quentin;
Craik, David J.

Publication type:

Article

Cationic Solution and Solid‐State Emitters – Robust Imaging Agents for Cells, Bacteria, and Protists.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 38, p. 1, doi. 10.1002/chem.202300334

By:

Dubbert, Justin;
Höing, Alexander;
Graupner, Nadine;
Rajter, Ľubomír;
Dunthorn, Micah;
Knauer, Shirley K.;
Galstyan, Anzhela;
Rizzo, Fabio;
Voskuhl, Jens

Publication type:

Article

Organoiridium Complexes Enhance Cellular Defense Against Reactive Aldehydes Species.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 36, p. 1, doi. 10.1002/chem.202300842

By:

Jana, Rahul D.;
Ngo, Anh H.;
Bose, Sohini;
Do, Loi H.

Publication type:

Article

Rationalizing the Optimization of Detergents for Membrane Protein Purification.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 30, p. 1, doi. 10.1002/chem.202300159

By:

Urner, Leonhard H.;
Junge, Florian;
Fiorentino, Francesco;
El‐Baba, Tarick J.;
Shutin, Denis;
Nölte, Gideon;
Haag, Rainer;
Robinson, Carol V.

Publication type:

Article

Optimization of G‐Quadruplex Ligands through a SAR Study Combining Parallel Synthesis and Screening of Cationic Bis(acylhydrazones).

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 4, p. 1, doi. 10.1002/chem.202202427

By:

Reznichenko, Oksana;
Leclercq, Denis;
Franco Pinto, Jaime;
Mouawad, Liliane;
Gabelica, Valérie;
Granzhan, Anton

Publication type:

Article

Carba‐Sugar Analogs of Glucosamine‐6‐Phosphate: New Activators for the glmS Riboswitch.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 3, p. 1, doi. 10.1002/chem.202202378

By:

Stängle, David;
Silkenath, Bjarne;
Gehle, Paul;
Esser, Anna;
Mayer, Günter;
Wittmann, Valentin

Publication type:

Article

A Small‐Molecule Probe with a Dual Function of miRNA Inhibition and Target identification.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 3, p. 1, doi. 10.1002/chem.202202013

By:

Wang, Weishan;
Deng, Jiafang;
Zhang, Yan;
Li, Jinbo

Publication type:

Article

Phomoxanthone A Targets ATP Synthase.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 70, p. 1, doi. 10.1002/chem.202202397

By:

Ali, Rameez;
Parelkar, Sangram S.;
Thompson, Paul R.;
Mitroka‐Batsford, Susan;
Yerramilli, Siddartha;
Scarlata, Suzanne F.;
Mistretta, Katelyn S.;
Coburn, Jeannine M.;
Mattson, Anita E.

Publication type:

Article

Improved Dye Survival in Expansion Microscopy through Stabilizer‐Conjugated Linkers.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 66, p. 1, doi. 10.1002/chem.202202404

By:

Wen, Gang;
Leen, Volker;
Jia, Yuqing;
Rohand, Taoufik;
Hofkens, Johan

Publication type:

Article

Enantioselective Approach for Expanding the Three‐Dimensional Space of Tetrahydroquinoline to Develop BET Bromodomain Inhibitors**.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 64, p. 1, doi. 10.1002/chem.202202293

By:

Lespinasse, Marie‐Ange;
Wei, Kaiyao;
Perrin, Justine;
Winkler, Matthias;
Hamaidia, Sieme;
Leroy, Alexis;
Macek Jilkova, Zuzana;
Philouze, Christian;
Marche, Patrice N.;
Petosa, Carlo;
Govin, Jérôme;
Emadali, Anouk;
Wong, Yung‐Sing

Publication type:

Article

Dihydroxy‐Acid Dehydratases From Pathogenic Bacteria: Emerging Drug Targets to Combat Antibiotic Resistance.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 44, p. 1, doi. 10.1002/chem.202200927

By:

Bayaraa, Tenuun;
Gaete, Jose;
Sutiono, Samuel;
Kurz, Julia;
Lonhienne, Thierry;
Harmer, Jeffrey R.;
Bernhardt, Paul V.;
Sieber, Volker;
Guddat, Luke;
Schenk, Gerhard

Publication type:

Article

Network pharmacological evaluation of strigolactones efficacy as potential inhibitors against therapeutic targets of hepatocellular carcinoma.

Published in:

Biotechnology Letters, 2022, v. 44, n. 7, p. 879, doi. 10.1007/s10529-022-03266-7

By:

Amod, Ayush;
Pahal, Sonu;
Choudhary, Princy;
Gupta, Ayushi;
Singh, Sangeeta

Publication type:

Article

Integrated bioinformatics based subtractive genomics approach to decipher the therapeutic function of hypothetical proteins from Salmonella typhi XDR H-58 strain.

Published in:

Biotechnology Letters, 2022, v. 44, n. 2, p. 279, doi. 10.1007/s10529-021-03219-6

By:

Khan, Kanwal;
Uddin, Reaz

Publication type:

Article

Repurposing a drug targeting peptide for targeting antimicrobial peptides against Staphylococcus.

Published in:

Biotechnology Letters, 2020, v. 42, n. 2, p. 287, doi. 10.1007/s10529-019-02779-y

By:

Choudhury, Ankan;
Islam, S. M. Ashiqul;
Ghidey, Meron R.;
Kearney, Christopher Michel

Publication type:

Article

Adiponectin predicts poor response to antidepressant drugs in major depressive disorder.

Published in:

Human Psychopharmacology: Clinical & Experimental, 2021, v. 36, n. 6, p. 1, doi. 10.1002/hup.2793

By:

Benedetti, Francesco;
Branchi, Igor;
Poletti, Sara;
Lorenzi, Cristina;
Bigai, Giorgia;
Colombo, Cristina;
Zanardi, Raffaella

Publication type:

Article

Exploring the potential and limitations of cyclopeptides as pharmaceutical drugs: a computational peptidology approach to the study of grassypeptolides A-G.

Published in:

Theoretical Chemistry Accounts: Theory, Computation, & Modeling, 2023, v. 142, n. 9, p. 1, doi. 10.1007/s00214-023-03031-7

By:

Flores-Holguín, Norma;
Frau, Juan;
Glossman-Mitnik, Daniel

Publication type:

Article

MRI after magnetic drug targeting in patients with advanced solid malignant tumors.

Published in:

2004

By:

Lemke, A.-J.;
Senfft von Pilsach, M.-I.;
Lübbe, A.;
Bergemann, C.;
Riess, H.;
Felix, R.;
Lübbe, A

Publication type:

journal article