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- Title
The Jackson toxic milk mouse as a model for copper loading.
- Authors
Coronado, Veronica; Nanji, Manoj; Cox, Diane W.
- Abstract
This article presents information on the Jackson toxic milk mouse as a model for copper loading. Copper is an essential trace element required for the normal biological function of several prokaryotic and eukaryotic enzymes. Excessive production of free radicals can result in tissue damage due to oxidative stress. Recently, free radical- induced oxidative stress has been implicated in a variety of neurological disorders, including Alzheimer disease, Parkinson disease, and amyotrophic lateral sclerosis.
- Subjects
COPPER; PARKINSON'S disease; ENZYMOLOGY; AMYOTROPHIC lateral sclerosis; ALZHEIMER'S disease; OXIDATIVE stress
- Publication
Mammalian Genome, 2001, Vol 12, Issue 10, p793
- ISSN
0938-8990
- Publication type
Academic Journal
- DOI
10.1007/s00335-001-3021-y