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Title

Analytical interference of intravascular contrast agents with clinical laboratory tests: a joint guideline by the ESUR Contrast Media Safety Committee and the Preanalytical Phase Working Group of the EFLM Science Committee.

Authors

van der Molen, Aart J.; Krabbe, Johannes G.; Dekkers, Ilona A.; Geenen, Remy W. F.; Bellin, Marie-France; Bertolotto, Michele; Brismar, Torkel B.; Cadamuro, Janne; Correas, Jean-Michel; Heinz-Peer, Gertraud; Langlois, Michel R.; Mahnken, Andreas H.; Ozben, Tomris; Quattrocchi, Carlo C.; Radbruch, Alexander; Reimer, Peter; Roditi, Giles; Romanini, Laura; Sebastià, Carmen; Simundic, Ana-Maria

Abstract

The Contrast Media Safety Committee of the European Society of Urogenital Radiology has, together with the Preanalytical Phase Working Group of the EFLM Science Committee, reviewed the literature and updated its recommendations to increase awareness and provide insight into these interferences. Clinical relevance statement: Contrast Media may interfere with clinical laboratory tests. Awareness of potential interference may prevent unwanted misdiagnosis. Key Points: • Contrast Media may interfere with clinical laboratory tests; therefore awareness of potential interference may prevent unwanted misdiagnosis. • Clinical Laboratory tests should be performed prior to radiological imaging with contrast media or alternatively, blood or urine collection should be delayed, depending on kidney function.

Subjects

CONTRAST media; PATHOLOGICAL laboratories; BLOOD collection; KIDNEY physiology; DIAGNOSTIC errors

Publication

European Radiology, 2024, Vol 34, Issue 7, p4821

ISSN

0938-7994

Publication type

Academic Journal

DOI

10.1007/s00330-023-10411-x

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