Works matching IS 0344-5704 AND VI 74 AND IP 5 AND DT 2014

Results: 27

A first-in-human study of the anti-α5β1 integrin monoclonal antibody PF-04605412 administered intravenously to patients with advanced solid tumors.

Published in:

2014

By:

Mateo, J;
Berlin, J;
de Bono, J S;
Cohen, R B;
Keedy, V;
Mugundu, G;
Zhang, Lianglin;
Abbattista, A;
Davis, C;
Gallo Stampino, C;
Borghaei, H

Publication type:

journal article

Pharmacokinetics of the chimeric anti-GD2 antibody, ch14.18, in children with high-risk neuroblastoma.

Published in:

2014

By:

Desai, Ami V;
Fox, Elizabeth;
Smith, L Mary;
Lim, Allison Pecha;
Maris, John M;
Balis, Frank M

Publication type:

journal article

GEIS 2013 guidelines for gastrointestinal sarcomas (GIST).

Published in:

2014

By:

Poveda, Andrés;
Del Muro, Xavier García;
López-Guerrero, Jose Antonio;
Martínez, Virginia;
Romero, Ignacio;
Valverde, Claudia;
Cubedo, Ricardo;
Martín-Broto, Javier

Publication type:

journal article

A phase I dose-escalation study of MEDI-575, a PDGFRα monoclonal antibody, in adults with advanced solid tumors.

Published in:

2014

By:

Becerra, Carlos R;
Conkling, Paul;
Vogelzang, Nicholas;
Wu, Hilary;
Hong, Shengyan;
Narwal, Rajesh;
Liang, Meina;
Tavakkoli, Fatemeh;
Pandya, Naimish

Publication type:

journal article

Mechanistic pharmacokinetic/pharmacodynamic modeling of in vivo tumor uptake, catabolism, and tumor response of trastuzumab maytansinoid conjugates.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 969, doi. 10.1007/s00280-014-2561-2

By:

Wada, Russ;
Erickson, Hans;
Lewis Phillips, Gail;
Provenzano, Carmela;
Leipold, Douglas;
Mai, Elaine;
Johnson, Holly;
Tibbitts, Jay

Publication type:

Article

A phase I trial of gemcitabine, S-1 and LV combination (GSL) therapy in advanced pancreatic cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 911, doi. 10.1007/s00280-014-2563-0

By:

Nakai, Yousuke;
Isayama, Hiroyuki;
Saito, Kei;
Sasaki, Takashi;
Takahara, Naminatsu;
Hamada, Tsuyoshi;
Mizuno, Suguru;
Miyabayashi, Koji;
Yamamoto, Keisuke;
Mohri, Dai;
Kogure, Hirofumi;
Yamamoto, Natsuyo;
Hirano, Kenji;
Ijichi, Hideaki;
Tateishi, Keisuke;
Tada, Minoru;
Koike, Kazuhiko

Publication type:

Article

Importance of branched-chain amino acids in patients with liver cirrhosis and advanced hepatocellular carcinoma receiving hepatic arterial infusion chemotherapy.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 899, doi. 10.1007/s00280-014-2564-z

By:

Kanekawa, Takenori;
Nagai, Hidenari;
Kanayama, Masahiro;
Sumino, Yasukiyo

Publication type:

Article

A phase I dose-escalation study of MEDI-575, a PDGFRα monoclonal antibody, in adults with advanced solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 917, doi. 10.1007/s00280-014-2567-9

By:

Becerra, Carlos;
Conkling, Paul;
Vogelzang, Nicholas;
Wu, Hilary;
Hong, Shengyan;
Narwal, Rajesh;
Liang, Meina;
Tavakkoli, Fatemeh;
Pandya, Naimish

Publication type:

Article

TACE plus sorafenib for the treatment of hepatocellular carcinoma: results of the multicenter, phase II SOCRATES trial.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 947, doi. 10.1007/s00280-014-2568-8

By:

Erhardt, Andreas;
Kolligs, Frank;
Dollinger, Matthias;
Schott, Eckart;
Wege, Hennig;
Bitzer, Michael;
Gog, Christiane;
Lammert, Frank;
Schuchmann, Markus;
Walter, Clemens;
Blondin, Dirk;
Ohmann, Christian;
Häussinger, Dieter

Publication type:

Article

A phase I and pharmacokinetic study of oral perifosine with different loading schedules in patients with refractory neoplasms.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 955, doi. 10.1007/s00280-014-2569-7

By:

Figg, William;
Monga, Manish;
Headlee, Donna;
Shah, Avni;
Chau, Cindy;
Peer, Cody;
Messman, Richard;
Elsayed, Yusri;
Murgo, Anthony;
Melillo, Giovanni;
Ryan, Qin;
Kalnitskiy, Mikhail;
Senderowicz, Adrian;
Hollingshead, Melinda;
Arbuck, Susan;
Sausville, Edward

Publication type:

Article

Evaluation of gefitinib efficacy according to body surface area in patients with non-small cell lung cancer harboring an EGFR mutation.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 939, doi. 10.1007/s00280-014-2570-1

By:

Igawa, Satoshi;
Kasajima, Masashi;
Ishihara, Mikiko;
Kimura, Michiko;
Hiyoshi, Yasuhiro;
Niwa, Hideyuki;
Kusuhara, Seiichiro;
Harada, Shinya;
Asakuma, Maiko;
Otani, Sakiko;
Katono, Ken;
Sasaki, Jiichiro;
Masuda, Noriyuki

Publication type:

Article

Effect of age on the pharmacokinetics of busulfan in patients undergoing hematopoietic cell transplantation; an alliance study (CALGB 10503, 19808, and 100103).

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 927, doi. 10.1007/s00280-014-2571-0

By:

Beumer, Jan;
Owzar, Kouros;
Lewis, Lionel;
Jiang, Chen;
Holleran, Julianne;
Christner, Susan;
Blum, William;
Devine, Steven;
Kolitz, Jonathan;
Linker, Charles;
Vij, Ravi;
Alyea, Edwin;
Larson, Richard;
Ratain, Mark;
Egorin, Merrill

Publication type:

Article

Non-surgical treatment versus radical esophagectomy for clinical T1N0M0 esophageal carcinoma: a single-center experience.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 995, doi. 10.1007/s00280-014-2573-y

By:

Park, Inkeun;
Kim, Yong-Hee;
Yoon, Dok;
Park, Sook;
Kim, Hyeong;
Kim, Jong;
Jung, Hwoon-Yong;
Lee, Gin;
Cho, Kyung-Ja;
Kim, Sung-Bae

Publication type:

Article

Expression of a novel peptide derived from PCNA damages DNA and reverses cisplatin resistance.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 981, doi. 10.1007/s00280-014-2574-x

By:

Lingeman, Robert;
Hickey, Robert;
Malkas, Linda

Publication type:

Article

Pharmacokinetics of the chimeric anti-G antibody, ch14.18, in children with high-risk neuroblastoma.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 1047, doi. 10.1007/s00280-014-2575-9

By:

Desai, Ami;
Fox, Elizabeth;
Smith, L.;
Lim, Allison;
Maris, John;
Balis, Frank

Publication type:

Article

A first-in-human study of the anti-α5β1 integrin monoclonal antibody PF-04605412 administered intravenously to patients with advanced solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 1039, doi. 10.1007/s00280-014-2576-8

By:

Mateo, J.;
Berlin, J.;
Bono, J.;
Cohen, R.;
Keedy, V.;
Mugundu, G.;
Zhang, Lianglin;
Abbattista, A.;
Davis, C.;
Gallo Stampino, C.;
Borghaei, H.

Publication type:

Article

Antitumor activity of the selective ALK inhibitor alectinib in models of intracranial metastases.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 1023, doi. 10.1007/s00280-014-2578-6

By:

Kodama, Tatsushi;
Hasegawa, Masami;
Takanashi, Kenji;
Sakurai, Yuji;
Kondoh, Osamu;
Sakamoto, Hiroshi

Publication type:

Article

Effectiveness and safety of cabazitaxel plus prednisolone chemotherapy for metastatic castration-resistant prostatic carcinoma: data on Korean patients obtained by the cabazitaxel compassionate-use program.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 1005, doi. 10.1007/s00280-014-2579-5

By:

Lee, Jae-Lyun;
Park, Se;
Koh, Su-Jin;
Lee, Se;
Kim, Yu;
Choi, Yoon;
Lee, Jihye;
Lim, Ho

Publication type:

Article

Leucovorin rescue allows effective high-dose pralatrexate treatment and an increase in therapeutic index in mesothelioma xenografts.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 1029, doi. 10.1007/s00280-014-2580-z

By:

Tedeschi, Philip;
Kathari, Yamini;
Farooqi, Iqra;
Bertino, Joseph

Publication type:

Article

Prognostic value of human papillomavirus in anal squamous cell carcinoma.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 1033, doi. 10.1007/s00280-014-2582-x

By:

Ravenda, Paola;
Magni, Elena;
Botteri, Edoardo;
Manzotti, Michela;
Barberis, Massimo;
Vacirca, Davide;
Trovato, Cristina;
Dell'Acqua, Veronica;
Leonardi, Maria;
Sideri, Mario;
Fazio, Nicola;
Zampino, Maria

Publication type:

Article

Clinical study of the novel cyclin-dependent kinase inhibitor dinaciclib in combination with rituximab in relapsed/refractory chronic lymphocytic leukemia patients.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 1057, doi. 10.1007/s00280-014-2583-9

By:

Fabre, Claire;
Gobbi, Marco;
Ezzili, Cyrine;
Zoubir, Mustapha;
Sablin, Marie-Paule;
Small, Karen;
Im, Ellie;
Shinwari, Nabeegha;
Zhang, Da;
Zhou, Honghong;
Tourneau, Christophe

Publication type:

Article

Heat shock protein 90 (HSP90) is overexpressed in p16-negative oropharyngeal squamous cell carcinoma, and its inhibition in vitro potentiates the effects of chemoradiation.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 1015, doi. 10.1007/s00280-014-2584-8

By:

Patel, Kirtesh;
Wen, Jing;
Magliocca, Kelly;
Muller, Susan;
Liu, Yuan;
Chen, Zhuo;
Saba, Nabil;
Diaz, Roberto

Publication type:

Article

Phase I trial of hepatic arterial infusion (HAI) of floxuridine with modified oxaliplatin, 5-fluorouracil and leucovorin (m-FOLFOX6) in Chinese patients with unresectable liver metastases from colorectal cancer.

Published in:

2014

By:

Li, Cong;
Gu, Yangkui;
Zhao, Ming;
Yuan, Yunfei;
Wang, Fenghua;
Wang, Zhiqiang;
Li, Wang;
Luo, Huiyan;
Chen, Cui;
Chen, Gong;
Ding, Peirong;
Wu, Xiaojun;
Lu, Zhenhai;
Pan, Zhizhong;
Xu, Ruihua;
He, Youjian;
Wan, Desen;
Li, Yuhong

Publication type:

Report

Significant association of combination of OCT4, NANOG, and SOX2 gene polymorphisms in susceptibility and response to treatment in North Indian breast cancer patients.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 1065, doi. 10.1007/s00280-014-2588-4

By:

Tulsyan, Sonam;
Agarwal, Gaurav;
Lal, Punita;
Mittal, Balraj

Publication type:

Article

A phase I, open-label, multicenter study to evaluate the pharmacokinetics and safety of oral panobinostat in patients with advanced solid tumors and various degrees of hepatic function.

Published in:

2014

By:

Slingerland, Marije;
Hess, Dagmar;
Clive, Sally;
Sharma, Sunil;
Sandstrom, Per;
Loman, Niklas;
Porro, Maria;
Mu, Song;
Waldron, Edward;
Valera, Sue-zette;
Gelderblom, Hans

Publication type:

Report

Predicting success in regulatory approval from Phase I results.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 1099, doi. 10.1007/s00280-014-2596-4

By:

Malik, Laeeq;
Mejia, Alex;
Parsons, Helen;
Ehler, Benjamin;
Mahalingam, Devalingam;
Brenner, Andrew;
Sarantopoulos, John;
Weitman, Steven

Publication type:

Article

GEIS 2013 guidelines for gastrointestinal sarcomas (GIST).

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 883, doi. 10.1007/s00280-014-2547-0

By:

Poveda, Andrés;
Muro, Xavier;
López-Guerrero, Jose;
Martínez, Virginia;
Romero, Ignacio;
Valverde, Claudia;
Cubedo, Ricardo;
Martín-Broto, Javier

Publication type:

Article