Works matching IS 0344-5704 AND VI 69 AND IP 6 AND DT 2012

Results: 34

RY10-4, a novel anti-tumor compound, exhibited its anti-angiogenesis activity by down-regulation of the HIF-1[alpha] and inhibition phosphorylation of AKT and mTOR.

Published in:

2012

By:

Liu Z;
Yuan Q;
Zhang X;
Xiong C;
Xue P;
Ruan J

Publication type:

Journal Article

A phase I trial of concurrent chemoradiotherapy with non-split administration of docetaxel and cisplatin for dry stage III non-small-cell lung cancer (JCOG9901DI).

Published in:

2012

By:

Hida N;
Okamoto H;
Misumi Y;
Sato A;
Ishii M;
Kashizaki F;
Shimokawa T;
Shimizu T;
Watanabe K;
Hida, Naoya;
Okamoto, Hiroaki;
Misumi, Yuuki;
Sato, Akira;
Ishii, Mari;
Kashizaki, Fumihiro;
Shimokawa, Tsuneo;
Shimizu, Teppei;
Watanabe, Koshiro

Publication type:

journal article

Phase I trial of the combination of flavopiridol and imatinib mesylate in patients with Bcr-Abl+ hematological malignancies.

Published in:

2012

By:

Bose P;
Perkins EB;
Honeycut C;
Wellons MD;
Stefan T;
Jacobberger JW;
Kontopodis E;
Beumer JH;
Egorin MJ;
Imamura CK;
Douglas Figg W Sr;
Karp JE;
Koc ON;
Cooper BW;
Luger SM;
Colevas AD;
Roberts JD;
Grant S;
Bose, Prithviraj;
Perkins, Edward B

Publication type:

journal article

An open-label, phase 1 study evaluating safety, tolerability, and pharmacokinetics of linifanib (ABT-869) in Japanese patients with solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1477, doi. 10.1007/s00280-012-1846-6

By:

Asahina, Hajime;
Tamura, Yosuke;
Nokihara, Hiroshi;
Yamamoto, Noboru;
Seki, Yoshitaka;
Shibata, Takashi;
Goto, Yasushi;
Tanioka, Maki;
Yamada, Yasuhide;
Coates, Andrew;
Chiu, Yi-Lin;
Li, Xiaohui;
Pradhan, Rajendra;
Ansell, Peter;
McKeegan, Evelyn;
McKee, Mark;
Carlson, Dawn;
Tamura, Tomohide

Publication type:

Article

A comprehensive safety analysis confirms rhabdomyolysis as an uncommon adverse reaction in patients treated with trabectedin.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1557, doi. 10.1007/s00280-012-1864-4

By:

Grosso, Federica;
D'Incalci, Maurizio;
Cartoafa, Mirela;
Nieto, Antonio;
Fernández-Teruel, Carlos;
Alfaro, Vicente;
Lardelli, Pilar;
Roy, Elena;
Gómez, Javier;
Kahatt, Carmen;
Soto-Matos, Arturo;
Judson, Ian

Publication type:

Article

FDG-PET as a pharmacodynamic biomarker for early assessment of treatment response to linifanib (ABT-869) in a non-small cell lung cancer xenograft model.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1669, doi. 10.1007/s00280-012-1840-z

By:

Mudd, Sarah;
Voorbach, Martin;
Reuter, David;
Tapang, Paul;
Hickson, Jonathan;
Refici-Buhr, Marion;
Fox, Gerard;
Albert, Daniel;
Luo, Yanping;
Day, Mark

Publication type:

Article

Ascorbic acid and healthy lymphocytes: a way to explain anticancer activity?

Published in:

2012

By:

Rodemeister, Sandra;
Nohr, Donatus;
Biesalski, Hans

Publication type:

Letter

Phase I trial of the combination of flavopiridol and imatinib mesylate in patients with Bcr-Abl hematological malignancies.

Published in:

2012

By:

Bose, Prithviraj;
Perkins, Edward;
Honeycut, Connie;
Wellons, Martha;
Stefan, Tammy;
Jacobberger, James;
Kontopodis, Emmanouil;
Beumer, Jan;
Egorin, Merrill;
Imamura, Chiyo;
Douglas Figg, W.;
Karp, Judith;
Koc, Omer;
Cooper, Brenda;
Luger, Selina;
Colevas, A.;
Roberts, John;
Grant, Steven

Publication type:

Report

The administration of gefitinib in patients with advanced non-small-cell lung cancer after the failure of erlotinib.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1407, doi. 10.1007/s00280-012-1848-4

By:

Grossi, Francesco;
Rijavec, Erika;
Dal Bello, Maria;
Defferrari, Carlotta;
Brianti, Annalisa;
Barletta, Giulia;
Genova, Carlo;
Murolo, Carmelina;
Cosso, Maurizio;
Fontanini, Gabriella;
Boldrini, Laura;
Truini, Mauro;
Pronzato, Paolo

Publication type:

Article

Phase I study of chidamide (CS055/HBI-8000), a new histone deacetylase inhibitor, in patients with advanced solid tumors and lymphomas.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1413, doi. 10.1007/s00280-012-1847-5

By:

Dong, Mei;
Ning, Zhi-Qiang;
Xing, Pu-Yuan;
Xu, Jia-Lian;
Cao, Hai-Xiang;
Dou, Gui-Fang;
Meng, Zhi-Yun;
Shi, Yuan-Kai;
Lu, Xian-Ping;
Feng, Feng-Yi

Publication type:

Article

Preclinical pharmacology of novel indolecarboxamide ML-970, an investigative anticancer agent.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1423, doi. 10.1007/s00280-012-1851-9

By:

Rayburn, Elizabeth;
Wang, Wei;
Li, Mao;
Zhang, Xu;
Xu, Hongxia;
Li, Haibo;
Qin, Jiang-Jiang;
Jia, Lee;
Covey, Joseph;
Lee, Moses;
Zhang, Ruiwen

Publication type:

Article

A single-dose placebo- and moxifloxacin-controlled study of the effects of temsirolimus on cardiac repolarization in healthy adults.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1433, doi. 10.1007/s00280-012-1845-7

By:

Boni, Joseph;
Leister, Cathie;
Hug, Bruce;
Burns, Jaime;
Sonnichsen, Daryl

Publication type:

Article

The T393C polymorphism of GNAS1 as a predictor for chemotherapy sensitivity and survival in advanced non-small-cell lung cancer patients treated with gemcitabine plus platinum.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1443, doi. 10.1007/s00280-012-1849-3

By:

Xie, Fa-Jun;
Zhao, Peng;
Kou, Jun-Yan;
Hong, Wei;
Fu, Li;
Hu, Lin;
Hong, Dan;
Su, Dan;
Gao, Yun;
Zhang, Yi-Ping

Publication type:

Article

Potent combination therapy for human breast tumors with high doses of 5-fluorouracil: remission and lack of host toxicity.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1449, doi. 10.1007/s00280-012-1842-x

By:

Al Safarjalani, Omar;
Rais, Reem;
Naguib, Fardos;
el Kouni, Mahmoud

Publication type:

Article

Phase I dose-escalation study of vinflunine hard capsules administered twice a day for 2 consecutive days every week in patients with advanced/metastatic solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1467, doi. 10.1007/s00280-012-1856-4

By:

Calvo, E.;
Vermorken, J.;
Hiret, S.;
Rodon, J.;
Cortes, J.;
Senellart, H.;
den Brande, J.;
Dyck, J.;
Pétain, A.;
Ferre, P.;
Bennouna, J.

Publication type:

Article

Decitabine triphosphate levels in peripheral blood mononuclear cells from patients receiving prolonged low-dose decitabine administration: a pilot study.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1457, doi. 10.1007/s00280-012-1850-x

By:

Jansen, Robert;
Rosing, Hilde;
Wijermans, Pierre;
Keizer, Ron;
Schellens, Jan;
Beijnen, Jos

Publication type:

Article

Neoadjuvant chemoradiotherapy with docetaxel, cisplatin, and 5-fluorouracil for esophageal cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1499, doi. 10.1007/s00280-012-1853-7

By:

Emi, Manabu;
Hihara, Jun;
Hamai, Yoichi;
Aoki, Yoshiro;
Okada, Morihito;
Kenjo, Masahiro;
Murakami, Yuji

Publication type:

Article

TH-302, a hypoxia-activated prodrug with broad in vivo preclinical combination therapy efficacy: optimization of dosing regimens and schedules.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1487, doi. 10.1007/s00280-012-1852-8

By:

Liu, Qian;
Sun, Jessica;
Wang, Jingli;
Ahluwalia, Dharmendra;
Baker, Amanda;
Cranmer, Lee;
Ferraro, Damien;
Wang, Yan;
Duan, Jian-Xin;
Ammons, W.;
Curd, John;
Matteucci, Mark;
Hart, Charles

Publication type:

Article

Phase I study of AEE788, a novel multitarget inhibitor of ErbB- and VEGF-receptor-family tyrosine kinases, in recurrent glioblastoma patients.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1507, doi. 10.1007/s00280-012-1854-6

By:

Reardon, David;
Conrad, Charles;
Cloughesy, Timothy;
Prados, Michael;
Friedman, Henry;
Aldape, Kenneth;
Mischel, Paul;
Xia, Jane;
DiLea, Clifford;
Huang, Jerry;
Mietlowski, William;
Dugan, Margaret;
Chen, Wei;
Yung, W.

Publication type:

Article

9-Amino acridine pharmacokinetics, brain distribution, and in vitro/in vivo efficacy against malignant glioma.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1519, doi. 10.1007/s00280-012-1855-5

By:

Teitelbaum, Aaron;
Gallardo, Jose;
Bedi, Jessica;
Giri, Rajan;
Benoit, Adam;
Olin, Michael;
Morizio, Kate;
Ohlfest, John;
Remmel, Rory;
Ferguson, David

Publication type:

Article

Phase I trial of irinotecan and amrubicin with granulocyte colony-stimulating factor support in extensive-stage small-cell lung cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1529, doi. 10.1007/s00280-012-1858-2

By:

Asakuma, Maiko;
Yamamoto, Michiko;
Wada, Mayuko;
Ryuge, Shinichiro;
Katono, Ken;
Yokoba, Masanori;
Fukui, Tomoya;
Takakura, Akira;
Otani, Sakiko;
Maki, Sachiyo;
Igawa, Satoshi;
Yanaihara, Tomoko;
Mitsufuji, Hisashi;
Kubota, Masaru;
Katagiri, Masato;
Sasaki, Jiichiro;
Masuda, Noriyuki

Publication type:

Article

Transient elevation of serum cystatin C concentrations during perioperative cisplatin-based chemotherapy in esophageal cancer patients.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1537, doi. 10.1007/s00280-012-1860-8

By:

Kume, Manabu;
Yasui, Hiroyuki;
Yoshikawa, Yutaka;
Horinouchi, Masanori;
Higashiguchi, Kanae;
Kobayashi, Yoko;
Kuroda, Daisuke;
Hirano, Takeshi;
Hirai, Midori;
Nakamura, Tsutomu

Publication type:

Article

Reply.

Published in:

2012

By:

Hadi, S.

Publication type:

Letter

The Rho kinase inhibitor fasudil is involved in p53-mediated apoptosis in human hepatocellular carcinoma cells.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1545, doi. 10.1007/s00280-012-1862-6

By:

Takeba, Yuko;
Matsumoto, Naoki;
Watanabe, Minoru;
Takenoshita-Nakaya, Sachiko;
Ohta, Yuki;
Kumai, Toshio;
Takagi, Masayuki;
Koizumi, Satoshi;
Asakura, Takeshi;
Otsubo, Takehito

Publication type:

Article

Novel physiologically based pharmacokinetic modeling of patupilone for human pharmacokinetic predictions.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1567, doi. 10.1007/s00280-012-1863-5

By:

Xia, Binfeng;
Heimbach, Tycho;
Lin, Tsu-han;
He, Handan;
Wang, Yanfeng;
Tan, Eugene

Publication type:

Article

Open-label, phase I, pharmacokinetic studies of abiraterone acetate in healthy men.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1583, doi. 10.1007/s00280-012-1865-3

By:

Acharya, M.;
Bernard, A.;
Gonzalez, M.;
Jiao, J.;
Vries, R.;
Tran, N.

Publication type:

Article

The value of genetic polymorphisms to predict toxicity in metastatic colorectal patients with irinotecan-based regimens.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1591, doi. 10.1007/s00280-012-1866-2

By:

Lamas, M.;
Duran, G.;
Balboa, E.;
Bernardez, B.;
Candamio, S.;
Vidal, Y.;
Mosquera, A.;
Giraldez, J.;
Lopez, R.;
Carracedo, A.;
Barros, F.

Publication type:

Article

Selective PI3K inhibition by BKM120 and BEZ235 alone or in combination with chemotherapy in wild-type and mutated human gastrointestinal cancer cell lines.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1601, doi. 10.1007/s00280-012-1869-z

By:

Mueller, Annett;
Bachmann, Erika;
Linnig, Monika;
Khillimberger, Katrin;
Schimanski, Carl;
Galle, Peter;
Moehler, Markus

Publication type:

Article

An SNP in CYP39A1 is associated with severe neutropenia induced by docetaxel.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1617, doi. 10.1007/s00280-012-1872-4

By:

Uchiyama, Toshitaka;
Kanno, Hitoshi;
Ishitani, Ken;
Fujii, Hisaichi;
Ohta, Hiroaki;
Matsui, Hideo;
Kamatani, Naoyuki;
Saito, Kayoko

Publication type:

Article

A phase I trial of concurrent chemoradiotherapy with non-split administration of docetaxel and cisplatin for dry stage III non-small-cell lung cancer (JCOG9901DI).

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1625, doi. 10.1007/s00280-012-1871-5

By:

Hida, Naoya;
Okamoto, Hiroaki;
Misumi, Yuuki;
Sato, Akira;
Ishii, Mari;
Kashizaki, Fumihiro;
Shimokawa, Tsuneo;
Shimizu, Teppei;
Watanabe, Koshiro

Publication type:

Article

RY10-4, a novel anti-tumor compound, exhibited its anti-angiogenesis activity by down-regulation of the HIF-1α and inhibition phosphorylation of AKT and mTOR.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1633, doi. 10.1007/s00280-012-1873-3

By:

Liu, Ziwei;
Yuan, Qianying;
Zhang, Xuenong;
Xiong, Chaomei;
Xue, Pingping;
Ruan, Jinlan

Publication type:

Article

FOLFIRI as second-line chemotherapy for advanced pancreatic cancer: a GISCAD multicenter phase II study.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1641, doi. 10.1007/s00280-012-1875-1

By:

Zaniboni, Alberto;
Aitini, Enrico;
Barni, Sandro;
Ferrari, Daris;
Cascinu, Stefano;
Catalano, Vincenzo;
Valmadre, Giuseppe;
Ferrara, Domenica;
Veltri, Enzo;
Codignola, Claudio;
Labianca, Roberto

Publication type:

Article

Lenalidomide in solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1393, doi. 10.1007/s00280-012-1874-2

By:

Segler, Angela;
Tsimberidou, Apostolia-Maria

Publication type:

Article

Loss of PTEN expression as a predictor of resistance to anti-EGFR monoclonal therapy in metastatic colorectal cancer: evidence from retrospective studies.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1647, doi. 10.1007/s00280-012-1886-y

By:

Wang, Zhen-Hua;
Gao, Qin-Yan;
Fang, Jing-Yuan

Publication type:

Article