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- Title
Combinational zimberelimab plus lenvatinib and chemotherapy for alpha-fetoprotein elevated, advanced gastric cancer patients (AFPGC): a phase 1 dose-escalation study.
- Authors
Deng, Ting; Wang, Feixue; Zhang, Le; Ning, Tao; Sun, Yansha; Ge, Shaohua; Bai, Ming; Lu, Yao; Li, Hongli; Ba, Yi
- Abstract
Alpha-fetoprotein elevated gastric cancer (AFPGC) got growing interests for its aggressive nature and unfavorable prognosis. Here, a phase 1 dose escalation study was conducted to evaluate safety and efficacy of zimberelimab (GLS-010, anti-PD-1) plus lenvatinib and chemotherapy (XELOX) as the first-line treatment for AFPGC.
- Publication
Cancer immunology, immunotherapy : CII, 2024, Vol 73, Issue 8, p154
- ISSN
1432-0851
- Publication type
Journal Article
- DOI
10.1007/s00262-024-03743-0