Works matching DE "CHECKPOINT kinase 1"

Results: 158
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    Regulation of CHK1 inhibitor resistance by a c-Rel and USP1 dependent pathway.

    Published in:
    Biochemical Journal, 2022, v. 479, n. 19, p. 2063, doi. 10.1042/BCJ20220102
    By:
    • Hunter, Jill E.;
    • Campbell, Amy E.;
    • Hannaway, Nicola L.;
    • Kerridge, Scott;
    • Luli, Saimir;
    • Butterworth, Jacqueline A.;
    • Sellier, Helene;
    • Mukherjee, Reshmi;
    • Dhillon, Nikita;
    • Sudhindar, Praveen D.;
    • Shukla, Ruchi;
    • Brownridge, Philip J.;
    • Bell, Hayden L.;
    • Coxhead, Jonathan;
    • Taylor, Leigh;
    • Leary, Peter;
    • Hasoon, Megan S. R.;
    • Collins, Ian;
    • Garrett, Michelle D.;
    • Eyers, Claire E.
    Publication type:
    Article
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    Mutation of the RelA(p65) Thr505 phosphosite disrupts the DNA replication stress response leading to CHK1 inhibitor resistance.

    Published in:
    Biochemical Journal, 2022, v. 479, n. 19, p. 2087, doi. 10.1042/BCJ20220089
    By:
    • Hunter, Jill E.;
    • Campbell, Amy E.;
    • Butterworth, Jacqueline A.;
    • Sellier, Helene;
    • Hannaway, Nicola L.;
    • Luli, Saimir;
    • Floudas, Achilleas;
    • Kenneth, Niall S.;
    • Moore, Adam J.;
    • Brownridge, Philip J.;
    • Thomas, Huw D.;
    • Coxhead, Jonathan;
    • Taylor, Leigh;
    • Leary, Peter;
    • Hasoon, Megan S. R.;
    • Knight, Andrew M.;
    • Garrett, Michelle D.;
    • Collins, Ian;
    • Eyers, Claire E.;
    • Perkins, Neil D.
    Publication type:
    Article
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    ATR Inhibition in Advanced Urothelial Carcinoma.

    Published in:
    Clinical Genitourinary Cancer, 2023, v. 21, n. 2, p. 203, doi. 10.1016/j.clgc.2022.10.016
    By:
    • Leibrandt, Ryan C.;
    • Mei-Juan Tu;
    • Ai-Ming Yu;
    • Lara, Primo N.;
    • Parikh, Mamta
    Publication type:
    Article
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    Targeting CLDN6 in germ cell tumors by an antibody-drug-conjugate and studying therapy resistance of yolk-sac tumors to identify and screen specific therapeutic options.

    Published in:
    Molecular Medicine, 2023, v. 29, n. 1, p. 1, doi. 10.1186/s10020-023-00636-3
    By:
    • Skowron, Margaretha A.;
    • Kotthoff, Mara;
    • Bremmer, Felix;
    • Ruhnke, Katja;
    • Parmaksiz, Fatma;
    • Richter, Annika;
    • Küffer, Stefan;
    • Reuter-Jessen, Kirsten;
    • Pauls, Stella;
    • Stefanski, Anja;
    • Ströbel, Philipp;
    • Stühler, Kai;
    • Nettersheim, Daniel
    Publication type:
    Article
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    Multiple 9-1-1 complexes promote homolog synapsis, DSB repair, and ATR signaling during mammalian meiosis.

    Published in:
    eLife, 2022, p. 1, doi. 10.7554/eLife.68677
    By:
    • Pereira, Catalina;
    • Arroyo-Martinez, Gerardo A.;
    • Guo, Matthew Z.;
    • Downey, Michael S.;
    • Kelly, Emma R.;
    • Grive, Kathryn J.;
    • Mahadevaiah, Shantha K.;
    • Sims, Jennie R.;
    • Faca, Vitor M.;
    • Tsai, Charlton;
    • Schiltz, Carl J.;
    • Wit, Niek;
    • Jacobs, Heinz;
    • Clark, Nathan L.;
    • Freire, Raimundo;
    • Turner, James;
    • Lyndaker, Amy M.;
    • Brieno-Enriquez, Miguel A.;
    • Cohen, Paula E.;
    • Smolka, Marcus B.
    Publication type:
    Article
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    BLM overexpression as a predictive biomarker for CHK1 inhibitor response in PARP inhibitor–resistant BRCA-mutant ovarian cancer.

    Published in:
    Science Translational Medicine, 2023, v. 15, n. 701, p. 1, doi. 10.1126/scitranslmed.add7872
    By:
    • Gupta, Nitasha;
    • Huang, Tzu-Ting;
    • Nair, Jayakumar R.;
    • An, Daniel;
    • Zurcher, Grant;
    • Lampert, Erika J.;
    • McCoy, Ann;
    • Cimino-Mathews, Ashley;
    • Swisher, Elizabeth M.;
    • Radke, Marc R.;
    • Lockwood, Christina M.;
    • Reichel, Jonathan B.;
    • Chiang, Chih-Yuan;
    • Wilson, Kelli M.;
    • Cheng, Ken Chih-Chien;
    • Nousome, Darryl;
    • Lee, Jung-Min
    Publication type:
    Article
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