Works matching Topoisomerase inhibitors


Results: 1709
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    Synthesis and evaluation of original bioisosteres of bacterial type IIA topoisomerases inhibitors.

    Published in:
    Canadian Journal of Chemistry, 2016, v. 94, n. 3, p. 240, doi. 10.1139/cjc-2015-0475
    By:
    • Petrella, Stéphanie;
    • Aubry, Alexandra;
    • Janvier, Geneviève;
    • Coutant, Eloi P.;
    • Cartier, Alex;
    • Dao, Thuy-Ha;
    • Bonhomme, Frédéric J.;
    • Motreff, Laurence;
    • Pissis, Cédric;
    • Bizet, Chantal;
    • Clermont, Dominique;
    • Begaud, Evelyne;
    • Retailleau, Pascal;
    • Munier-Lehmann, Hélène;
    • Capton, Estelle;
    • Mayer, Claudine;
    • Janin, Yves L.
    Publication type:
    Article
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    Investigating the potential anticancer activities of antibiotics as topoisomerase II inhibitors and DNA intercalators: in vitro, molecular docking, molecular dynamics, and SAR studies.

    Published in:
    Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2023.2171029
    By:
    • Farouk, Faten;
    • Elmaaty, Ayman Abo;
    • Elkamhawy, Ahmed;
    • Tawfik, Haytham O.;
    • Alnajjar, Radwan;
    • Abourehab, Mohammed A. S.;
    • Saleh, Mohamed A.;
    • Eldehna, Wagdy M.;
    • Al‐Karmalawy, Ahmed A.
    Publication type:
    Article
    31

    Design and synthesis of novel rigid dibenzo[b,f]azepines through ring closure technique as promising anticancer candidates against leukaemia and acting as selective topoisomerase II inhibitors and DNA intercalators.

    Published in:
    Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2022.2157825
    By:
    • El-Behairy, Mohammed Farrag;
    • Abd-Allah, Walaa Hamada;
    • Khalifa, Mohamed M.;
    • Nafie, Mohamed S.;
    • Saleh, Mohamed A.;
    • Abdel-Maksoud, Mohammed S.;
    • Al-Warhi, Tarfah;
    • Eldehna, Wagdy M.;
    • Al‐Karmalawy, Ahmed A.
    Publication type:
    Article
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