Title: False-positive 16α-[<sup>18</sup>F]Fluoro-17β-Estradiol PET/CT in benign cartilaginous tumor.
Authors: Mazet, Réjane; Bailly, Matthieu; Champeaux-Orange, Elise; Breton, Jeanne; Torossian, Nouritza; Metrard, Gilles
Abstract: The article discusses a case of a 67-year-old woman with a history of breast cancer who presented with back pain and was found to have a benign cartilaginous tumor in her spine. The use of 16α-[18F]Fluoro-17β-Estradiol (FES) PET/CT initially suggested bone metastasis, but further tests confirmed the benign nature of the tumor. The article highlights the importance of caution when interpreting FES-PET/CT results, as false-positive uptake can occur in benign cartilaginous lesions due to estrogen receptor expression.
Subjects: BREAST cancer surgery; LUMBAR pain; RADIATION pneumonitis; SMOOTH muscle tumors; GROWTH plate; ESTROGEN receptors; TERIPARATIDE
Publication: European Journal of Nuclear Medicine & Molecular Imaging, 2025, Vol 52, Issue 2, p779
ISSN: 1619-7070
Publication type: Academic Journal
DOI: 10.1007/s00259-024-06883-8

False-positive 16α-[<sup>18</sup>F]Fluoro-17β-Estradiol PET/CT in benign cartilaginous tumor.

Mazet, Réjane; Bailly, Matthieu; Champeaux-Orange, Elise; Breton, Jeanne; Torossian, Nouritza; Metrard, Gilles