[⁶⁸Ga]Ga-FAPI-04 PET/CT imaging of a patient with neurosyphilis mimicking intracranial malignant tumor.

Liu, Hongjun; Li, Chongjiao; Xiao, Zhiwei; Tian, Yueli; Lu, Nan; He, Yong

The article in the European Journal of Nuclear Medicine & Molecular Imaging discusses a case where a 71-year-old male patient with symptoms of fatigue and numbness was initially suspected to have a cerebral infarction but was later diagnosed with neurosyphilis mimicking an intracranial malignant tumor. Various imaging techniques, including [68Ga] Ga-FAPI-04 PET/CT, were used to detect the lesions, leading to the correct diagnosis of syphilitic encephalitis. The study highlights the potential of FAPI tracers in diagnosing both malignant and non-malignant diseases with high FAP expression in inflammatory and fibrotic tissues.

CROHN'S disease; IMAGE analysis; COMPUTED tomography; CEREBRAL infarction; INTRACRANIAL tumors

European Journal of Nuclear Medicine & Molecular Imaging, 2024, Vol 51, Issue 13, p4179

1619-7070

Academic Journal

10.1007/s00259-024-06821-8