Title: First-time imaging of [<sup>89</sup>Zr]trastuzumab in breast cancer using a long axial field-of-view PET/CT scanner.
Authors: Brouwers, Adrienne H.; van Sluis, Joyce; van Snick, Johannes H.; Schröder, Carolina P.; Baas, Inge O.; Boellaard, Ronald; Glaudemans, Andor W. J. M.; Borra, Ronald J. H.; Lammertsma, Adriaan A.; Dierckx, Rudi A. J. O.; Tsoumpas, Charalampos
Abstract: One important advantage of using LAFOV PET/CT for imaging SP 89 sp Zr-labelled monoclonal antibodies (mAbs), i.e., immunoPET, is the substantial increase in sensitivity compared with standard axial field-of-view (SAFOV) PET/CT systems, which may lead to a remarkable image quality improvement. This article is part of the Topical Collection on Image of the month Long axial field-of-view (LAFOV) PET/CT scanners have been introduced recently [[1]], which offer numerous advantages [[3]]. Both patients were informed about the study aims, procedures (one additional PET/CT scan on the same day with the planned PET/CT), and the need to acquire an additional low-dose CT scan.
Subjects: TRASTUZUMAB; BREAST cancer; SCANNING systems; COINCIDENCE; HER2 positive breast cancer
Publication: European Journal of Nuclear Medicine & Molecular Imaging, 2022, Vol 49, Issue 10, p3593
ISSN: 1619-7070
Publication type: Academic Journal
DOI: 10.1007/s00259-022-05777-x

First-time imaging of [<sup>89</sup>Zr]trastuzumab in breast cancer using a long axial field-of-view PET/CT scanner.

Brouwers, Adrienne H.; van Sluis, Joyce; van Snick, Johannes H.; Schröder, Carolina P.; Baas, Inge O.; Boellaard, Ronald; Glaudemans, Andor W. J. M.; Borra, Ronald J. H.; Lammertsma, Adriaan A.; Dierckx, Rudi A. J. O.; Tsoumpas, Charalampos