Works matching DE "SMALL molecules"

Results: 5000

Data-driven discovery of chemical signatures for developing new inhibitors against human influenza viruses.

Published in:

BMC Chemistry, 2025, v. 19, n. 1, p. 1, doi. 10.1186/s13065-025-01540-z

By:

Kharatyan, Levon;
Gevorgyan, Smbat;
Khachatryan, Hamlet;
Shavina, Anastasiya;
Hakobyan, Astghik;
Matevosyan, Mher;
Zakaryan, Hovakim

Publication type:

Article

Exploring the Adsorption Features of Furan and 1,n‐Dioxane as Environmental Toxins on Two‐Dimensional RuC Nanosheet: A DFT Study.

Published in:

ChemistryOpen, 2025, v. 14, n. 6, p. 1, doi. 10.1002/open.202400415

By:

Mahmoud, Amna H. M.;
Aziz, Muhrail E. S.;
Rabee, Abdallah I. M.;
El‐Tayeb, Mohamed A.;
Mekhemer, Gamal A. H.;
Shoeib, Tamer;
Ibrahim, Mahmoud A. A.

Publication type:

Article

Repurposing of the small-molecule adrenoreceptor-inhibitor carvedilol for treatment of the fibrotic lung.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1534989

By:

Jordan, Maria;
Schmidt, Kevin;
Fuchs, Maximilian;
Just, Annette;
Pfanne, Angelika;
Willmer, Lena;
Neubert, Lavinia;
Werlein, Christopher;
Zardo, Patrick;
Pich, Andreas;
Thum, Thomas;
Fiedler, Jan

Publication type:

Article

Machine learning-driven identification of exosome- related biomarkers in head and neck squamous cell carcinoma.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1590331

By:

He, Yaodong;
Li, Yun;
Tang, Jiaqi;
Wang, Yan;
Zhao, Zhenyan;
Liu, Rong;
Yang, Zihui;
Li, Huan;
Wei, Jianhua

Publication type:

Article

Casein kinase 1 epsilon (CK1ε) as a potential therapeutic target in chronic liver disease.

Published in:

Journal of Veterinary Science, 2025, v. 26, n. 3, p. 1, doi. 10.4142/jvs.24321

By:

Leya, Mwense;
Thach Phan Van;
Jong-Won Kim;
Bumseok Kim

Publication type:

Article

ELF1-mediated transactivation of METTL3/YTHDF2 promotes nucleus pulposus cell senescence via m6A-dependent destabilization of E2F3 mRNA in intervertebral disc degeneration.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02515-8

By:

Liu, Xiao-Wei;
Xu, Hao-Wei;
Zhang, Shu-Bao;
Yi, Yu-Yang;
Chang, Sheng-Jie;
Wang, Shan-Jin

Publication type:

Article

三维电解-Fenton 法处理垃圾膜浓缩液试验.

Published in:

Journal of Guilin University of Technology, 2025, v. 45, n. 1, p. 95, doi. 10.3969/j.issn.1674-9057.2025.01.011

By:

王潇潇;
钟溢健;
李金城;
陆祖贤;
罗雪静;
朱红祥

Publication type:

Article

The Effect of Crocin on Oxidative Stress Compared to Saffron Aqueous Extract, Glycerol and Myoinositol in Diabetic Rats.

Published in:

Journal of Nutrition & Food Security, 2025, v. 10, n. 2, p. 259, doi. 10.18502/jnfs.v10i2.18538

By:

Mohyadini, Matin;
Shirali, Saeed;
Bathaie, S. Zahra

Publication type:

Article

肿瘤靶向放射性诊疗药物创新研发策略.

Published in:

Atomic Energy Science & Technology, 2025, v. 59, n. 4, p. 769, doi. 10.7538/yzk.2024.youxian.0191

By:

黄旭虎;
陈欢;
李可欣;
王宁;
庄津;
李洪玉;
杜进

Publication type:

Article

Efficient Non‐Volatile WORM Memory Devices from Ferrocene Functionalized Quinoxaline Systems.

Published in:

Chemistry - An Asian Journal, 2025, v. 20, n. 10, p. 1, doi. 10.1002/asia.202401888

By:

Gayathri, Ramesh;
Akshaya, Madanan;
Imran, Predhanekar Mohemad;
Bhuvanesh, Nattamai S. P.;
Nagarajan, Samuthira

Publication type:

Article

Metal‐Free, Blue‐Light‐Mediated Radical Trifluoromethylation of Small Organic Molecules.

Published in:

Chemistry - An Asian Journal, 2025, v. 20, n. 10, p. 1, doi. 10.1002/asia.202401666

By:

Sahni, Priya;
Bandyopadhyay, Kamalika;
Swarnakar, Alok K.;
Pal, Amlan K.

Publication type:

Article

Insights into the gut-liver axis: mechanisms and emerging therapies in hepatocellular carcinoma.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1595853

By:

Hu, Yongjian;
Gao, Mingming;
Chenghuang, Jiajin;
Bao, Rui

Publication type:

Article

A Review on Phytoconstituents for the Management of Psoriasis.

Published in:

Natural Product Communications, 2025, v. 20, n. 5, p. 1, doi. 10.1177/1934578X251342473

By:

Yamuna, K;
Priyanka Dwarampudi, L;
Shanmugam, Ramaswamy;
Mirunalini, G;
Dutta, Subhajit;
Nagaprasad, N;
Krishnaraj, Ramaswamy

Publication type:

Article

Impact of Melatonin on Brain Metabolism in Diabetes: A Narrative Review.

Published in:

Natural Product Communications, 2025, v. 20, n. 5, p. 1, doi. 10.1177/1934578X251340772

By:

Nwaji, Azubuike Raphael;
Bisong, Sunday Agba;
Antai, Atim Bassey;
Okakpu, Chika Maryjane;
Okechukwu, Miracle Princess;
Igwe, Esther Onyinyechi;
Okafor, Chidiebube Sylvia;
Odoh, Precious Chinenye;
Chukwu, Maryjane Chiamaka;
Esinulo, Joyful Idimmachi;
Simon, Toochukwu;
Igbinedion, Deborah Esohe;
Ogbonna, Kingsley Godspower

Publication type:

Article

Inhibitory Effect of Three Flavonoids on Xanthine Oxidase Activity.

Published in:

Journal of Chinese Institute of Food Science & Technology / Zhongguo Shipin Xuebao, 2025, v. 25, n. 3, p. 104, doi. 10.16429/j.1009-7848.2025.03.011

By:

ZHANG Yingxin;
BAN Chenyu;
SU Dongyu;
LIU Yi;
ZHOU Suzhen;
FAN Jinbo

Publication type:

Article

A homogeneous immunoassay technology based on liposomes and the complement system enables one-step, no-wash, rapid diagnostics directly in serum.

Published in:

Analytical & Bioanalytical Chemistry, 2025, v. 417, n. 15, p. 3257, doi. 10.1007/s00216-025-05882-4

By:

Hoecherl, Kilian;
Streif, Simon;
Spitzenberg, Clemens;
Rink, Simone;
Behrent, Arne;
Holzhausen, Ferdinand;
Griesche, Christian;
Rogoll, Cornelia;
Foedlmeier, Maximilian;
Gebhard, Anna;
Kulikowski, Kacper;
Schaefer, Nicole;
Pauly, Diana;
Baeumner, Antje J.

Publication type:

Article

Biomedical Application of Nanogels: From Cancer to Wound Healing.

Published in:

Molecules, 2025, v. 30, n. 10, p. 2144, doi. 10.3390/molecules30102144

By:

Zafaryab, Mohammad;
Vig, Komal

Publication type:

Article

NOTA and NODAGA Radionuclide Complexing Agents: Versatile Approaches for Advancements in Radiochemistry.

Published in:

Molecules, 2025, v. 30, n. 10, p. 2095, doi. 10.3390/molecules30102095

By:

Chambers, Claudia G.;
Wang, Jing;
Sakr, Tamer M.;
Miao, Yubin;
Smith, Charles J.

Publication type:

Article

Engineering of Corynebacterium glutamicum for the synthesis of aromatic compounds.

Published in:

Applied Microbiology & Biotechnology, 2025, v. 109, n. 1, p. 1, doi. 10.1007/s00253-025-13520-3

By:

Marienhagen, Jan

Publication type:

Article

Validation of Interaction Between Sugarcane miR167d and Predicted Target Gene ScPUM1 and Analysis of Their Expression Under Cold Stress: A Novel Mechanism of miR167d.

Published in:

Journal of Plant Growth Regulation, 2025, v. 44, n. 5, p. 2379, doi. 10.1007/s00344-024-11554-x

By:

Song, Qiqi;
Zhu, Pengjin;
Li, Jiahui;
Cheng, Qin;
Tan, Qinliang;
Zhou, Quanguang;
Lv, Ping;
Nong, Zemei

Publication type:

Article

LC-MS/MS Determination of Quorum Sensing Molecules in Plasma from Burn Patients with Septic Shock Sustained by Acinetobacter Baumannii.

Published in:

Antibiotics (2079-6382), 2025, v. 14, n. 5, p. 517, doi. 10.3390/antibiotics14050517

By:

Carpenito, Nicolò;
Leporati, Marta;
Sciarrillo, Alberto;
Pensa, Anna;
Gambino, Roberto;
Musso, Giovanni;
Mella, Alberto;
Biancone, Luigi;
Risso, Daniela;
Mariano, Filippo;
Cosseddu, Domenico

Publication type:

Article

Prediction of circRNA–miRNA Interaction Using Graph Attention Network Based on Molecular Attributes and Biological Networks.

Published in:

Processes, 2025, v. 13, n. 5, p. 1318, doi. 10.3390/pr13051318

By:

Almotilag, Abdullah;
Elbashir, Murtada K.;
Mahmood, Mahmood A.;
Mohammed, Mohanad

Publication type:

Article

Analysis of the Application of Cryptophane-A\-E in a Mass-Sensing Methane Gas Sensor: Insights from a Numerical Simulation.

Published in:

Chemosensors, 2025, v. 14, n. 5, p. 179, doi. 10.3390/chemosensors13050179

By:

Liu, Xinlei;
Xiao, Dan;
Zhang, Qinglan;
Guan, Yu;
Shen, Bin;
Li, Jiazhe

Publication type:

Article

A Case of Localised Immediate Hypersensitivity Reaction to Bimekizumab.

Published in:

Contact Dermatitis (01051873), 2025, v. 92, n. 6, p. 488, doi. 10.1111/cod.14774

By:

Lasheras‐Pérez, Miguel Antonio;
López‐Salgueiro, Ramón;
Palacios‐Diaz, Rodolfo David;
Pujol‐Marco, Conrad;
Botella‐Estrada, Rafael;
Ibañez‐Echevarría, Ethel

Publication type:

Article

Nanoplatforms Targeting Intrinsically Disordered Protein Aggregation for Translational Neuroscience Applications.

Published in:

Nanomaterials (2079-4991), 2025, v. 15, n. 10, p. 704, doi. 10.3390/nano15100704

By:

Lo, Chih Hung;
Cheong, Lenny Yi Tong;
Zeng, Jialiu

Publication type:

Article

Targeting the Electron Transport System for Enhanced Longevity.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 614, doi. 10.3390/biom15050614

By:

Radovic, Marko;
Gartzke, Lucas P.;
Wink, Simon E.;
van der Kleij, Joris A.;
Politiek, Frouwkje A.;
Krenning, Guido

Publication type:

Article

Identifying Molecular Properties of Ataxin-2 Inhibitors for Spinocerebellar Ataxia Type 2 Utilizing High-Throughput Screening and Machine Learning.

Published in:

Biology (2079-7737), 2025, v. 14, n. 5, p. 522, doi. 10.3390/biology14050522

By:

Sahay, Smita;
Wen, Jingran;
Scoles, Daniel R.;
Simeonov, Anton;
Dexheimer, Thomas S.;
Jadhav, Ajit;
Kales, Stephen C.;
Sun, Hongmao;
Pulst, Stefan M.;
Facelli, Julio C.;
Jones, David E.

Publication type:

Article

Marine Bioactive Peptides—Structure, Function, and Application 2.0.

Published in:

Marine Drugs, 2025, v. 23, n. 5, p. 192, doi. 10.3390/md23050192

By:

Wang, Bin;
Chi, Chang-Feng

Publication type:

Article

Research advancements of antibody drug conjugates in non-small cell lung cancer with HER2 alterations.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06589-x

By:

Liu, Jiang;
Liu, Jianhua;
Yu, Jianhe;
Ren, Qun;
Cai, Yin;
Chen, Dadong;
Song, Chuanjun

Publication type:

Article

Structural Insights into Benzothiazole Derivatives as Modulators of Dehaloperoxidase: A Docking Study.

Published in:

Bulletin of Pure & Applied Sciences-Chemistry, 2024, v. 43, n. 2, p. 69

By:

Sur, Souvik

Publication type:

Article

Unraveling the cohesin-chromatin interface: identifying protein interactions that modulate chromosome structure and function.

Published in:

Epigenetics & Chromatin, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s13072-025-00596-4

By:

Rittenhouse, Natalie L.;
Gohil, Riya;
Arricastres, June E.;
Dowen, Jill M.

Publication type:

Article

De Novo Assembly and Comparative Analysis of the Mitochondrial Genomes for Six Rubus Species.

Published in:

Horticulturae, 2025, v. 11, n. 5, p. 559, doi. 10.3390/horticulturae11050559

By:

Shi, Yujie;
Chen, Zhen;
Jiang, Jingyong;
Li, Qianfan;
Zeng, Wei

Publication type:

Article

Inefficiency Rates of Biological Immunosuppressive Induction Agents Used in Organ Transplantation: A Pharmacovigilance Study.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 10, p. 3409, doi. 10.3390/jcm14103409

By:

Butuca, Anca;
Stoicescu, Laurentiu;
Popa, Mirela Livia;
Dobrea, Carmen Maximiliana;
Muntean, Adriana;
Morgovan, Claudiu;
Pienar, Corina;
Gligor, Felicia Gabriela;
Ghibu, Steliana;
Popa Ilie, Ioana Rada;
Frum, Adina

Publication type:

Article

Raising the bar in migraine prevention: Toward freedom and optimal control.

Published in:

Cephalalgia, 2025, v. 45, n. 5, p. 1, doi. 10.1177/03331024251331198

By:

Russo, Antonio;
Reuter, Uwe

Publication type:

Article

Autophagy as a potential therapeutic target in regulating improper cellular proliferation.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1579183

By:

Kumar, Prashant;
Choudhary, Akash;
Kinger, Sumit;
Jagtap, Yuvraj Anandrao;
Prajapati, Vijay Kumar;
Chitkara, Deepak;
Chinnathambi, Subashchandrabose;
Verma, Rahul Kumar;
Mishra, Amit

Publication type:

Article

Based on small molecules: development and application of fibroblast activation protein inhibitors radiopharmaceutical in tumor precision therapy.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1593380

By:

Luo, Yihui;
Fu, Haitian;
Yu, Chunjing

Publication type:

Article

Exosome, an important transmitter in the drug resistance of non-small cell lung cancer.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1539047

By:

Ji, Hongzhi;
Zhang, Li;
Ye, Lingyun

Publication type:

Article

Corrigendum: Gatifloxacin hydrochloride confers broad-spectrum antibacterial activity against phytopathogenic bacteria.

Published in:

2025

By:

Huang, Yanxia;
Peng, Bin;
Li, Chenhui;
Wu, Yuqin;
Zeng, Zixian;
Tariq, Moh;
Jiang, Lin;
Li, Shun-xiang;
Wu, Dousheng

Publication type:

Correction Notice

West Nile virus - a re-emerging global threat: recent advances in vaccines and drug discovery.

Published in:

Frontiers in Cellular & Infection Microbiology, 2025, p. 1, doi. 10.3389/fcimb.2025.1568031

By:

Kocabiyik, Deren Zehra;
Álvarez, Lizdany Flórez;
Durigon, Edison Luiz;
Wrenger, Carsten

Publication type:

Article

Reduced Genetic Diversity of Key Fertility and Vector Competency Related Genes in Anopheles gambiae s.l. Across Sub-Saharan Africa.

Published in:

Genes, 2025, v. 16, n. 5, p. 543, doi. 10.3390/genes16050543

By:

Seck, Fatoumata;
Diop, Mouhamadou Fadel;
Mané, Karim;
Diallo, Amadou;
Dieng, Idrissa;
Namountougou, Moussa;
Diabate, Abdoulaye;
Amambua-Ngwa, Alfred;
Dia, Ibrahima;
Assogba, Benoit Sessinou

Publication type:

Article

Advanced Therapies for Inflammatory Bowel Disease and Risk of Skin Cancer: What's New?

Published in:

Cancers, 2025, v. 17, n. 10, p. 1710, doi. 10.3390/cancers17101710

By:

Bencardino, Sarah;
Bernardi, Francesca;
Allocca, Mariangela;
Zilli, Alessandra;
Furfaro, Federica;
Peyrin-Biroulet, Laurent;
Danese, Silvio;
D'Amico, Ferdinando

Publication type:

Article

Chondrosarcoma: Multi-Targeting Therapeutic Effects of Doxorubicin, BEZ235, and the Small Molecule Aspartyl-Asparaginyl-β-hydroxylase Inhibitor SMI1182.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1671, doi. 10.3390/cancers17101671

By:

Fife, Megan;
Tong, Ming;
Das, Bhaskar;
Rodriguez, Rene;
Chokkalingam, Parthiban;
Carlson, Rolf I.;
de la Monte, Suzanne M.

Publication type:

Article

Virtual Screening and Molecular Dynamics Simulation Targeting the ATP Domain of African Swine Fever Virus Type II DNA Topoisomerase.

Published in:

Viruses (1999-4915), 2025, v. 17, n. 5, p. 681, doi. 10.3390/v17050681

By:

Zhao, Rui;
Hou, Lezi;
Tesfagaber, Weldu;
Song, Linfei;
Zhang, Zhenjiang;
Li, Fang;
Bu, Zhigao;
Zhao, Dongming

Publication type:

Article

Activation of Small Molecules by Readily Accessible Alkylborane‐Based Frustrated Lewis Pairs.

Published in:

European Journal of Inorganic Chemistry, 2025, v. 28, n. 15, p. 1, doi. 10.1002/ejic.202500104

By:

Averdunk, Arthur;
Wech, Felix;
Becker, Jonathan;
Gellrich, Urs

Publication type:

Article

Genome-Wide Identification of UGT Gene Family and Functional Analysis of PgUGT29 in Platycodon grandiflorus.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4832, doi. 10.3390/ijms26104832

By:

Fan, Jizhou;
Rao, Weiyi;
Peng, Daiyin;
Wei, Tao;
Xing, Shihai

Publication type:

Article

Alleviation of Neurological Disorders by Targeting Neurodegenerative-Associated Enzymes: Natural and Synthetic Molecules.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4707, doi. 10.3390/ijms26104707

By:

Singh, Alka Ashok;
Khan, Fazlurrahman;
Song, Minseok

Publication type:

Article

Efficient Design of Affilin ® Protein Binders for HER3.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4683, doi. 10.3390/ijms26104683

By:

Diaz-Rovira, Anna M.;
Lotze, Jonathan;
Hoffmann, Gregor;
Pallara, Chiara;
Molina, Alexis;
Coburger, Ina;
Gloser-Bräunig, Manja;
Meysing, Maren;
Zwarg, Madlen;
Díaz, Lucía;
Guallar, Victor;
Bosse-Doenecke, Eva;
Roda, Sergi

Publication type:

Article

Symmetry‐Breaking Strategy Yields Dopant‐Free Small Molecule Hole Transport Materials for Inorganic Perovskite Solar Cells with 20.58% Efficiency and Outstanding Stability.

Published in:

Angewandte Chemie, 2025, v. 137, n. 23, p. 1, doi. 10.1002/ange.202502478

By:

Cai, Huimin;
Zhu, Qiliang;
Pan, Tianchen;
Wu, Lunbi;
Gu, Xin;
Duan, Chenghao;
Xiong, Liangbin;
Wu, Jiaying;
Liu, Sha;
Yu, Liyang;
Li, Ruipeng;
Yan, Keyou;
Ma, Ruijie;
Liu, Shengjian;
Jia, Tao;
Li, Gang

Publication type:

Article

In Situ Sprayed Self‐Gelling Powder Self‐Assembled by a Pure Molecular Drug from Herbal Extract for Rapid Hemostasis and Neuroprotection in Traumatic Brain Injury.

Published in:

Advanced Functional Materials, 2025, v. 35, n. 22, p. 1, doi. 10.1002/adfm.202419613

By:

Li, Teng;
Zheng, Jun;
Xia, Mingyue;
Zhu, Haonan;
Song, Xianwen;
Zhou, Yaya;
Yin, Chao;
Yu, Zhe;
Hu, En;
Cai, Zexuan;
Wu, Yao;
Zhu, Wenxin;
Luo, Weikang;
Cheng, Menghan;
Tang, Tao;
Zhang, Yi;
Wang, Yang

Publication type:

Article

CB5712809, a novel Keap1 inhibitor upregulates SQSTM1/p62 mediated Nrf2 activation to induce cell death in colon cancer cells.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02787-7

By:

Dera, Ayed A.;
Al Fayi, Majed

Publication type:

Article