Works matching DE "DRUG metabolism -- Evaluation"
Results: 61
Metabolic Syndrome in Severe Mental Disorders.
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- Metabolic Syndrome & Related Disorders, 2011, v. 9, n. 2, p. 91, doi. 10.1089/met.2010.0053
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- Article
Considerations and recent advances in QSAR models for cytochrome P450-mediated drug metabolism prediction.
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- Journal of Computer-Aided Molecular Design, 2008, v. 22, n. 11, p. 843, doi. 10.1007/s10822-008-9225-4
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- Article
Modeling chemical reactions for drug design.
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- Journal of Computer-Aided Molecular Design, 2007, v. 21, n. 1-3, p. 33, doi. 10.1007/s10822-006-9097-4
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- Article
A Critical Appraisal of the Role of Insulin Analogues in the Management of Diabetes Mellitus.
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- Drugs, 2005, v. 65, n. 3, p. 325, doi. 10.2165/00003495-200565030-00003
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- Article
Spatio-Temporal Simulation of First Pass Drug Perfusion in the Liver.
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- PLoS Computational Biology, 2014, v. 10, n. 3, p. 1, doi. 10.1371/journal.pcbi.1003499
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- Article
Substrate Profiling of Glutathione S-transferase with Engineered Enzymes and Matched Glutathione Analogues.
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- Angewandte Chemie, 2014, v. 126, n. 28, p. 7277, doi. 10.1002/ange.201402000
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- Article
Investigation of the Distribution of Polysaccharides in Polar and Nonpolar Systems and in Various Tissues of the Organism.
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- Pharmaceutical Chemistry Journal, 2004, v. 38, n. 1, p. 31, doi. 10.1023/B:PHAC.0000027642.58599.14
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- Article
A simple test for acetylator phenotype using caffeine.
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- British Journal of Clinical Pharmacology, 2004, v. 58, n. 7, p. S788, doi. 10.1111/j.1365-2125.2004.02297.x
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- Article
Commentaries.
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- British Journal of Clinical Pharmacology, 2004, v. 58, n. 7, p. S794, doi. 10.1111/j.1365-2125.2004.02276.x
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- Article
The effect of dosing regimen on the pharmacokinetics of risedronate.
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- British Journal of Clinical Pharmacology, 1999, v. 48, n. 4
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- Article
Pharmacokinetics and pharmacodynamics of allopurinol in elderly and young subjects.
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- British Journal of Clinical Pharmacology, 1999, v. 48, n. 4
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- Publication type:
- Article
Stereoselective pharmacokinetics of ketoprofen and ketoprofen glucuronide in end-stage renal disease: evidence for a ‘futile cycle’ of elimination.
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- British Journal of Clinical Pharmacology, 1999, v. 48, n. 4
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- Publication type:
- Article
Comprehensive evaluation of a novel nuclear factor-kappaB inhibitor, quinoclamine, by transcriptomic analysis.
- Published in:
- 2009
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- Publication type:
- journal article
Comparative genomics of xenobiotic metabolism: a porcine-human PXR gene comparison.
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- Mammalian Genome, 2007, v. 18, n. 3, p. 210, doi. 10.1007/s00335-007-9007-7
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- Publication type:
- Article
P-glycoprotein plays a role in the oral absorption of BMS-387032, a potent cyclin-dependent kinase 2 inhibitor, in rats.
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- Cancer Chemotherapy & Pharmacology, 2005, v. 55, n. 2, p. 110, doi. 10.1007/s00280-004-0873-3
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- Article
Critical evaluation of permeation enhancers for oral mucosal drug delivery.
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- Drug Development & Industrial Pharmacy, 2010, v. 36, n. 3, p. 254, doi. 10.3109/03639040903117348
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- Article
Effect of Excipient and Processing Variables on Adhesive Properties and Release Profile of Pentoxifylline From Mucoadhesive Tablets.
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- Drug Development & Industrial Pharmacy, 2006, v. 32, n. 3, p. 377, doi. 10.1080/03639040500519367
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- Publication type:
- Article
Expression of human papillomavirus type 16 E5 protein in amelanotic melanoma cells regulates endo-cellular pH and restores tyrosinase activity.
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- Journal of Experimental & Clinical Cancer Research (17569966), 2009, v. 28, p. 1, doi. 10.1186/1756-9966-28-4
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- Publication type:
- Article
Rat poorly predicts the combined non-absorbed and presystemically metabolized fractions in the human.
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- Xenobiotica, 2013, v. 43, n. 7, p. 607, doi. 10.3109/00498254.2012.752117
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- Article
The long, hard road: drug metabolism in the lifetime of the DMDG.
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- Xenobiotica, 2001, v. 31, n. 8/9, p. 459, doi. 10.1080/00498250110052742
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- Article
Mutual Prodrug Concept: Fundamentals and Applications.
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- Indian Journal of Pharmaceutical Sciences, 2006, v. 68, n. 3, p. 286
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- Article
The interpretation of hair analysis for drugs and drug metabolites.
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- Clinical Toxicology (15563650), 2018, v. 56, n. 2, p. 90, doi. 10.1080/15563650.2017.1379603
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- Article
Characterization of oxidative phenotype in a pediatric population of Tlaltizapan, Morelos, Mexico.
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- Acta Pediatrica de Mexico, 2008, v. 29, n. 2, p. 57
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- Article
Off-label drug use among hospitalised children: identifying areas with the highest need for research.
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- Pharmacy World & Science, 2008, v. 30, n. 5, p. 497, doi. 10.1007/s11096-008-9193-8
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- Article
Propafenone: An Effective Agent for the Management of Supraventricular Arrhythmias.
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- Journal of Cardiovascular Electrophysiology, 1996, v. 7, n. 4, p. 353, doi. 10.1111/j.1540-8167.1996.tb00537.x
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- Publication type:
- Article
Six novel UDP-glucuronosyltransferase (UGT1A3) polymorphisms with varying activity.
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- Journal of Human Genetics, 2004, v. 49, n. 3, p. 123, doi. 10.1007/s10038-003-0119-y
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- Article
Small animal clinical pharmacology and therapeutics - Edited by DM Booth.
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- 2012
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- Publication type:
- Book Review
GC-MS and LC-(high-resolution)-MS studies on the metabolic fate and detectability of camfetamine in rat urine.
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- Analytical & Bioanalytical Chemistry, 2014, v. 406, n. 16, p. 3815, doi. 10.1007/s00216-014-7796-6
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- Article
Modulation of apoptosis by HIV protease inhibitors.
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- Apoptosis, 2002, v. 7, n. 4, p. 295, doi. 10.1023/A:1016168411221
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- Article
Probing the links between in vitro potency, ADMET and physicochemical parameters.
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- 2011
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- Publication type:
- journal article
Pharmacogenetics in drug discovery and development: a translational perspective.
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- Nature Reviews Drug Discovery, 2008, v. 7, n. 10, p. 807, doi. 10.1038/nrd2593
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- Article
Combinatorial Pharmacogenetics.
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- Nature Reviews Drug Discovery, 2005, v. 4, n. 11, p. 911, doi. 10.1038/nrd1874
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- Publication type:
- Article
Elucidating mechanisms of drug-induced toxicity.
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- Nature Reviews Drug Discovery, 2005, v. 4, n. 5, p. 410, doi. 10.1038/nrd1720
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- Article
Drugs as materials: valuing physical form in drug discovery.
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- Nature Reviews Drug Discovery, 2004, v. 3, n. 11, p. 926, doi. 10.1038/nrd1550
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- Article
Implications of Protein Flexibility for Drug Discovery.
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- Nature Reviews Drug Discovery, 2003, v. 2, n. 7, p. 527, doi. 10.1038/nrd1129
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- Publication type:
- Article
Therapeutic drug monitoring in neuropsychopharmacology: does it hold its promises?
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- European Archives of Psychiatry & Clinical Neuroscience, 2008, v. 258, p. 21, doi. 10.1007/s00406-007-1005-y
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- Publication type:
- Article
Opinion: Gut microorganisms, mammalian metabolism and personalized health care.
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- Nature Reviews Microbiology, 2005, v. 3, n. 5, p. 431, doi. 10.1038/nrmicro1152
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- Article
Age-related differences in susceptibility to toxic effects of valproic acid in rats.
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- Journal of Applied Toxicology, 2008, v. 28, n. 5, p. 628, doi. 10.1002/jat.1314
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- Article
Clinical manifestations of disturbances in granulopoiesis kinetics: Idiosyncratic agranulocytosis.
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- Archives of Hellenic Medicine / Arheia Ellenikes Iatrikes, 2011, v. 28, n. 4, p. 439
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- Publication type:
- Article
Maximal Load of the Vitamin B12 Transport System: A Study on Mice Treated for Four Weeks with High-Dose Vitamin B12 or Cobinamide.
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- PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0046657
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- Article
Absence of Association between N-Acetyltransferase 2 Acetylator Status and Colorectal Cancer Susceptibility: Based on Evidence from 40 Studies.
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- PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0032425
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- Publication type:
- Article
P. falciparum In Vitro Killing Rates Allow to Discriminate between Different Antimalarial Mode-of-Action.
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- PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0030949
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- Article
Cytochrome P450 Reductase: A Harbinger of Diffusible Reduced Oxygen Species.
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- PLoS ONE, 2010, v. 5, n. 10, p. 1, doi. 10.1371/journal.pone.0013272
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- Article
Inhibition and induction of human cytochrome P450 (CYP) enzymes.
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- Xenobiotica, 1998, v. 28, n. 12, p. 1203, doi. 10.1080/004982598238886
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- Publication type:
- Article
Epigenomics and Interindividual Differences in Drug Response.
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- Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 6, p. 727, doi. 10.1038/clpt.2012.152
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- Publication type:
- Article
OII-C-2.
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- Clinical Pharmacology & Therapeutics, 2006, v. 79, n. 2, p. P6, doi. 10.1016/j.clpt.2005.12.019
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- Publication type:
- Article
Impairment of the metabolism of dipyrone in asymptomatic carriers of the hepatitis-B virus does not occur in rapid acetylators.
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- European Journal of Clinical Pharmacology, 2001, v. 57, n. 6/7, p. 461, doi. 10.1007/s002280100341
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- Publication type:
- Article
Olanzapine disposition in humans is unrelated to CYP1A2 and CYP2D6 phenotypes.
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- European Journal of Clinical Pharmacology, 2001, v. 57, n. 6/7, p. 493, doi. 10.1007/s002280100343
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- Publication type:
- Article
Differential Effects of Ornithine Enantiomers on the Activity of Anti-oxidant Enzymes, Polyamines Content, and Growth of Tobacco Cells under Osmotic Stresses.
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- Chirality, 2013, v. 25, n. 10, p. 583, doi. 10.1002/chir.22173
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- Publication type:
- Article
Recent Advances in the Clinical Pharmacology of Benzodiazepines Part I: Pharmacokinetics.
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- Human Psychopharmacology: Clinical & Experimental, 1987, v. 2, n. 1, p. 3, doi. 10.1002/hup.470020103
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- Publication type:
- Article