Lipidomic analysis.

Holčapek, Michal; Liebisch, Gerhard; Ekroos, Kim

The growth of the field of lipidomic analysis is enormous with numerous papers published annually, as shown on the statistics from Web of Science for keywords "lipidomic(s)" and "mass spectrometry" (Fig. The detailed analysis of these papers shows the approximate relative portions for major analytical approaches in lipidomic analysis: 59% liquid chromatography, 29% shotgun (direct infusion), and 12% mass spectrometry imaging. Is almost exclusively based on mass spectrometry (MS) analysis [[7]], starting from low-resolution analyzers (typical QqQ), now shifting more towards tandem mass analyzers with ultrahigh resolving power, e.g., Orbitraps.

SUPERCRITICAL fluid chromatography; MASS spectrometry; BUTYL methyl ether; BLOOD plasma

Analytical & Bioanalytical Chemistry, 2020, Vol 412, Issue 10, p2187

1618-2642

Academic Journal

10.1007/s00216-020-02419-9