Bioinspired recognition elements for mycotoxin sensors.

Peltomaa, Riikka; Benito-Peña, Elena; Moreno-Bondi, María C.

Mycotoxins are low molecular weight molecules produced as secondary metabolites by filamentous fungi that can be found as natural contaminants in many foods and feeds. These toxins have been shown to have adverse effects on both human and animal health, and are the cause of significant economic losses worldwide. Sensors for mycotoxin analysis have traditionally applied elements of biological origin for the selective recognition purposes. However, since the 1970s there has been an exponential growth in the use of genetically engineered or synthetic biomimetic recognition elements that allow some of the limitations associated with the use of natural receptors for the analyses of these toxins to be circumvented. This review provides an overview of recent advances in the application of bioinspired recognition elements, including recombinant antibodies, peptides, aptamers, and molecularly imprinted polymers, to the development of sensors for mycotoxins based on different transduction elements.

MYCOTOXINS; DETECTORS; BIOMIMETIC chemicals; IMPRINTED polymers; MOLECULAR weights

Analytical & Bioanalytical Chemistry, 2018, Vol 410, Issue 3, p747

1618-2642

Academic Journal

10.1007/s00216-017-0701-3