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Title: Elastic and inelastic light scattering spectroscopy and its possible use for label-free brain tumor typing.
Authors: Ostertag, Edwin; Stefanakis, Mona; Rebner, Karsten; Kessler, Rudolf
Abstract: This paper presents an approach for label-free brain tumor tissue typing. For this application, our dual modality microspectroscopy system combines inelastic Raman scattering spectroscopy and Mie elastic light scattering spectroscopy. The system enables marker-free biomedical diagnostics and records both the chemical and morphologic changes of tissues on a cellular and subcellular level. The system setup is described and the suitability for measuring morphologic features is investigated.
Subjects: BRAIN tumors; LIGHT scattering; RAMAN scattering; HISTOCOMPATIBILITY testing; CENTRAL nervous system tumors; ELECTROMAGNETIC wave scattering
Publication: Analytical & Bioanalytical Chemistry, 2017, Vol 409, Issue 28, p6613
ISSN: 1618-2642
Publication type: Academic Journal
DOI: 10.1007/s00216-017-0614-1

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Elastic and inelastic light scattering spectroscopy and its possible use for label-free brain tumor typing.