Works matching IS 00281298 AND DT 2008 AND VI 377 AND IP 4-6

Results: 36

Recent progresses in the experimental methods and evaluation strategies of transporter functions for the prediction of the pharmacokinetics in humans.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 617, doi. 10.1007/s00210-008-0312-9

By:

Kitamura, Satoshi;
Maeda, Kazuya;
Sugiyama, Yuichi

Publication type:

Article

Brain angiotensin receptors and binding proteins.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 283, doi. 10.1007/s00210-007-0238-7

By:

Speth, Robert;
Karamyan, Vardan

Publication type:

Article

Epac: effectors and biological functions.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 345, doi. 10.1007/s00210-007-0246-7

By:

Roscioni, Sara;
Elzinga, Carolina;
Schmidt, Martina

Publication type:

Article

Prothymosin α plays a key role in cell death mode-switch, a new concept for neuroprotective mechanisms in stroke.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 315, doi. 10.1007/s00210-007-0254-7

By:

Ueda, Hiroshi

Publication type:

Article

Peroxisome proliferator activated receptor γ and oxidized docosahexaenoic acids as new class of ligand.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 541, doi. 10.1007/s00210-007-0251-x

By:

Itoh, Toshimasa;
Yamamoto, Keiko

Publication type:

Article

Effect of P2 receptor on the intracellular calcium increase by cancer cells in human umbilical vein endothelial cells.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 429, doi. 10.1007/s00210-007-0259-2

By:

Nejime, Namie;
Tanaka, Naoko;
Yoshihara, Ryoko;
Kagota, Satomi;
Yoshikawa, Noriko;
Nakamura, Kazuki;
Kunitomo, Masaru;
Hashimoto, Michio;
Shinozuka, Kazumasa

Publication type:

Article

Impairment of endothelium-dependent ACh-induced relaxation in aorta of diabetic db/db mice—possible dysfunction of receptor and/or receptor–G protein coupling.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 401, doi. 10.1007/s00210-008-0261-3

By:

Miike, Tomohiro;
Kunishiro, Kazuyoshi;
Kanda, Mamoru;
Azukizawa, Satoru;
Kurahashi, Kazuyoshi;
Shirahase, Hiroaki

Publication type:

Article

Misinterpretation of the effect of amlodipine on cytosolic calcium concentration with fura-2 fluorospectrometry.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 423, doi. 10.1007/s00210-007-0243-x

By:

Asai, Masayoshi;
Takeuchi, Kazuhiko;
Uchida, Shinya;
Urushida, Tsuyoshi;
Katoh, Hideki;
Satoh, Hiroshi;
Yamada, Shizuo;
Hayashi, Hideharu;
Watanabe, Hiroshi

Publication type:

Article

On the analysis of ligand-directed signaling at G protein-coupled receptors.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 549, doi. 10.1007/s00210-008-0260-4

By:

Ehlert, Frederick

Publication type:

Article

A selective T-type Ca2+ channel blocker R(−) efonidipine.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 411, doi. 10.1007/s00210-007-0239-6

By:

Shin, Min-Chul;
Kim, Chang-Ju;
Min, Byung-Il;
Ogawa, Sachie;
Tanaka, Eiichiro;
Akaike, Norio

Publication type:

Article

Free fatty acids induce cholecystokinin secretion through GPR120.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 523, doi. 10.1007/s00210-007-0200-8

By:

Tanaka, Toshiki;
Katsuma, Susumu;
Adachi, Tetsuya;
Koshimizu, Taka-aki;
Hirasawa, Akira;
Tsujimoto, Gozoh

Publication type:

Article

Candidate gene polymorphisms predicting individual sensitivity to opioids.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 269, doi. 10.1007/s00210-007-0205-3

By:

Kasai, Shinya;
Hayashida, Masakazu;
Sora, Ichiro;
Ikeda, Kazutaka

Publication type:

Article

A novel mechanism of mechanical stress-induced angiotensin II type 1–receptor activation without the involvement of angiotensin II.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 393, doi. 10.1007/s00210-007-0215-1

By:

Yasuda, Noritaka;
Akazawa, Hiroshi;
Qin, Yingjie;
Zou, Yunzeng;
Komuro, Issei

Publication type:

Article

Signal transduction underlying the control of urinary bladder smooth muscle tone by muscarinic receptors and β-adrenoceptors.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 449, doi. 10.1007/s00210-007-0208-0

By:

Frazier, Elfaridah;
Peters, Stephan;
Braverman, Alan;
Ruggieri, Michael;
Michel, Martin

Publication type:

Article

Dopamine transporter mutant mice in experimental neuropharmacology.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 301, doi. 10.1007/s00210-007-0216-0

By:

Gainetdinov, Raul

Publication type:

Article

In vivo characterization of muscarinic receptors in peripheral tissues: evaluation of bladder selectivity of anticholinergic agents to treat overactive bladder.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 463, doi. 10.1007/s00210-007-0207-1

By:

Maruyama, Shuji;
Hasuike, Naoki;
Suzuki, Kazuhiro;
Yamada, Shizuo

Publication type:

Article

Cordycepin (3′-deoxyadenosine) inhibits the growth of B16-BL6 mouse melanoma cells through the stimulation of adenosine A3 receptor followed by glycogen synthase kinase-3β activation and cyclin D1 suppression.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 591, doi. 10.1007/s00210-007-0218-y

By:

Yoshikawa, Noriko;
Yamada, Shizuo;
Takeuchi, Chihiro;
Kagota, Satomi;
Shinozuka, Kazumasa;
Kunitomo, Masaru;
Nakamura, Kazuki

Publication type:

Article

Mediation of β-endorphin in andrographolide-induced plasma glucose-lowering action in type I diabetes-like animals.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 529, doi. 10.1007/s00210-007-0240-0

By:

Yu, Bu;
Chang, Cheng;
Su, Chih;
Cheng, Juei

Publication type:

Article

Effects of ursodeoxycholic acid on the pharmacokinetics and pharmacodynamics of intravenous and oral midazolam in healthy volunteers.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 629, doi. 10.1007/s00210-007-0217-z

By:

Yan, Dongmei;
Yang, Yingbao;
Uchida, Sinya;
Misaka, Shingen;
Luo, Jinghui;
Takeuchi, Kazuhiko;
Inui, Naoki;
Yamada, Shizuo;
Ohashi, Kyoichi;
Watanabe, Hiroshi

Publication type:

Article

Expression and functional role of β-adrenoceptors in the human urinary bladder urothelium.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 473, doi. 10.1007/s00210-008-0274-y

By:

Otsuka, Atsushi;
Shinbo, Hitoshi;
Matsumoto, Rikiya;
Kurita, Yutaka;
Ozono, Seiichiro

Publication type:

Article

Cloning and characterization of the rat free fatty acid receptor GPR120: in vivo effect of the natural ligand on GLP-1 secretion and proliferation of pancreatic β cells.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 515, doi. 10.1007/s00210-007-0250-y

By:

Tanaka, Toshiki;
Yano, Takeaki;
Adachi, Tetsuya;
Koshimizu, Taka-aki;
Hirasawa, Akira;
Tsujimoto, Gozoh

Publication type:

Article

Ab initio fragment molecular orbital study of ligand binding to human progesterone receptor ligand-binding domain.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 607, doi. 10.1007/s00210-008-0268-9

By:

Harada, Takanori;
Yamagishi, Kenji;
Nakano, Tatsuya;
Kitaura, Kazuo;
Tokiwa, Hiroaki

Publication type:

Article

5th International Symposium on receptor mechanisms, signal transduction and drug effects.

Published in:

2008

By:

Yamada, Shizuo;
Ehlert, Fred;
Hollenberg, Morley

Publication type:

Editorial

Acute inhibitory effect of dronedarone, a noniodinated benzofuran analogue of amiodarone, on Na+/Ca2+ exchange current in guinea pig cardiac ventricular myocytes.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 371, doi. 10.1007/s00210-008-0270-2

By:

Watanabe, Yasuhide;
Kimura, Junko

Publication type:

Article

Does anticholinergic medication have a role in treating men with overactive bladder and benign prostatic hyperplasia?

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 491, doi. 10.1007/s00210-007-0242-y

By:

Lee, Kyu-Sung;
Lee, Hye;
Han, Deok

Publication type:

Article

Transcriptional regulation of human UGT1A1 gene expression through distal and proximal promoter motifs: implication of defects in the UGT1A1 gene promoter.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 597, doi. 10.1007/s00210-007-0226-y

By:

Sugatani, Junko;
Mizushima, Kousuke;
Osabe, Makoto;
Yamakawa, Kasumi;
Kakizaki, Satoru;
Takagi, Hitoshi;
Mori, Masatomo;
Ikari, Akira;
Miwa, Masao

Publication type:

Article

Structure-activity relationship of vasoactive intestinal peptide (VIP): potent agonists and potential clinical applications.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 579, doi. 10.1007/s00210-007-0232-0

By:

Onoue, Satomi;
Misaka, Shingen;
Yamada, Shizuo

Publication type:

Article

Pharmacokinetics and pharmacodynamics of erythropoietin receptor in healthy volunteers.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 637, doi. 10.1007/s00210-007-0225-z

By:

Krzyzanski, Wojciech;
Wyska, Elzbieta

Publication type:

Article

Muscarinic receptor subtypes involved in carbachol-induced contraction of mouse uterine smooth muscle.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 503, doi. 10.1007/s00210-007-0223-1

By:

Kitazawa, Takio;
Hirama, Ryuichi;
Masunaga, Kozue;
Nakamura, Tatsuro;
Asakawa, Koichi;
Cao, Jinshan;
Teraoka, Hiroki;
Unno, Toshihiro;
Komori, Sei-ichi;
Yamada, Masahisa;
Wess, Jürgen;
Taneike, Tetsuro

Publication type:

Article

Down-regulation of TRPM6-mediated magnesium influx by cyclosporin A.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 333, doi. 10.1007/s00210-007-0212-4

By:

Ikari, Akira;
Okude, Chiaki;
Sawada, Hayato;
Takahashi, Tadanobu;
Sugatani, Junko;
Miwa, Masao

Publication type:

Article

Therapeutic receptor targets for lower urinary tract dysfunction.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 437, doi. 10.1007/s00210-007-0209-z

By:

Yoshimura, Naoki;
Kaiho, Yasuhiro;
Miyazato, Minoru;
Yunoki, Takakazu;
Tai, Changfeng;
Chancellor, Michael;
Tyagi, Pradeep

Publication type:

Article

The activation of transient receptor potential vanilloid receptor subtype 1 by capsaicin without extracellular Ca2+ is involved in the mechanism of distinct substance P release in cultured rat dorsal root ganglion neurons.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 325, doi. 10.1007/s00210-007-0211-5

By:

Tang, He-Bin;
Nakata, Yoshihiro

Publication type:

Article

At the frontline of Alzheimer’s disease treatment: γ-secretase inhibitor/modulator mechanism.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 295, doi. 10.1007/s00210-007-0206-2

By:

Tomita, Taisuke

Publication type:

Article

Therapeutic effects of the putative P2X3/P2X2/3 antagonist A-317491 on cyclophosphamide-induced cystitis in rats.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 483, doi. 10.1007/s00210-007-0197-z

By:

Ito, Katsuaki;
Iwami, Akihito;
Katsura, Hiromi;
Ikeda, Masahiro

Publication type:

Article

Adenylyl cyclase type 6 overexpression selectively enhances β-adrenergic and prostacyclin receptor-mediated inhibition of cardiac fibroblast function because of colocalization in lipid rafts.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 359, doi. 10.1007/s00210-007-0196-0

By:

Liu, Xiaoqiu;
Thangavel, Muthusamy;
Sun, Shu;
Kaminsky, Joseph;
Mahautmr, Penden;
Stitham, Jeremiah;
Hwa, John;
Ostrom, Rennolds

Publication type:

Article

Proteinases, proteinase-activated receptors (PARs) and the pathophysiology of cancer and diseases of the cardiovascular, musculoskeletal, nervous and gastrointestinal systems.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 4-6, p. 377, doi. 10.1007/s00210-007-0194-2

By:

Hansen, Kristina;
Oikonomopoulou, Katerina;
Li, Yang;
Hollenberg, Morley

Publication type:

Article

Works matching IS 00281298 AND DT 2008 AND VI 377 AND IP 4-6

Recent progresses in the experimental methods and evaluation strategies of transporter functions for the prediction of the pharmacokinetics in humans.

Brain angiotensin receptors and binding proteins.

Epac: effectors and biological functions.

Prothymosin α plays a key role in cell death mode-switch, a new concept for neuroprotective mechanisms in stroke.

Peroxisome proliferator activated receptor γ and oxidized docosahexaenoic acids as new class of ligand.

Effect of P2 receptor on the intracellular calcium increase by cancer cells in human umbilical vein endothelial cells.

Impairment of endothelium-dependent ACh-induced relaxation in aorta of diabetic db/db mice—possible dysfunction of receptor and/or receptor–G protein coupling.

Misinterpretation of the effect of amlodipine on cytosolic calcium concentration with fura-2 fluorospectrometry.

On the analysis of ligand-directed signaling at G protein-coupled receptors.

A selective T-type Ca<sup>2+</sup> channel blocker R(−) efonidipine.

Free fatty acids induce cholecystokinin secretion through GPR120.

Candidate gene polymorphisms predicting individual sensitivity to opioids.

A novel mechanism of mechanical stress-induced angiotensin II type 1–receptor activation without the involvement of angiotensin II.

Signal transduction underlying the control of urinary bladder smooth muscle tone by muscarinic receptors and β-adrenoceptors.

Dopamine transporter mutant mice in experimental neuropharmacology.

In vivo characterization of muscarinic receptors in peripheral tissues: evaluation of bladder selectivity of anticholinergic agents to treat overactive bladder.

Cordycepin (3′-deoxyadenosine) inhibits the growth of B16-BL6 mouse melanoma cells through the stimulation of adenosine A<sub>3</sub> receptor followed by glycogen synthase kinase-3β activation and cyclin D<sub>1</sub> suppression.

Mediation of β-endorphin in andrographolide-induced plasma glucose-lowering action in type I diabetes-like animals.

Effects of ursodeoxycholic acid on the pharmacokinetics and pharmacodynamics of intravenous and oral midazolam in healthy volunteers.

Expression and functional role of β-adrenoceptors in the human urinary bladder urothelium.

Cloning and characterization of the rat free fatty acid receptor GPR120: in vivo effect of the natural ligand on GLP-1 secretion and proliferation of pancreatic β cells.

Ab initio fragment molecular orbital study of ligand binding to human progesterone receptor ligand-binding domain.

5th International Symposium on receptor mechanisms, signal transduction and drug effects.

Acute inhibitory effect of dronedarone, a noniodinated benzofuran analogue of amiodarone, on Na<sup>+</sup>/Ca<sup>2+</sup> exchange current in guinea pig cardiac ventricular myocytes.

Does anticholinergic medication have a role in treating men with overactive bladder and benign prostatic hyperplasia?

Transcriptional regulation of human UGT1A1 gene expression through distal and proximal promoter motifs: implication of defects in the UGT1A1 gene promoter.

Structure-activity relationship of vasoactive intestinal peptide (VIP): potent agonists and potential clinical applications.

Pharmacokinetics and pharmacodynamics of erythropoietin receptor in healthy volunteers.

Muscarinic receptor subtypes involved in carbachol-induced contraction of mouse uterine smooth muscle.

Down-regulation of TRPM6-mediated magnesium influx by cyclosporin A.

Therapeutic receptor targets for lower urinary tract dysfunction.

The activation of transient receptor potential vanilloid receptor subtype 1 by capsaicin without extracellular Ca<sup>2+</sup> is involved in the mechanism of distinct substance P release in cultured rat dorsal root ganglion neurons.

At the frontline of Alzheimer’s disease treatment: γ-secretase inhibitor/modulator mechanism.

Therapeutic effects of the putative P2X<sub>3</sub>/P2X<sub>2/3</sub> antagonist A-317491 on cyclophosphamide-induced cystitis in rats.

Adenylyl cyclase type 6 overexpression selectively enhances β-adrenergic and prostacyclin receptor-mediated inhibition of cardiac fibroblast function because of colocalization in lipid rafts.

Proteinases, proteinase-activated receptors (PARs) and the pathophysiology of cancer and diseases of the cardiovascular, musculoskeletal, nervous and gastrointestinal systems.