Works matching IS 03405761 AND DT 2020 AND VI 94 AND IP 9

Results: 30

Discovery of treatment for nerve agents targeting a new metabolic pathway.
Published in:
Archives of Toxicology, 2020, v. 94, n. 9, p. 3249, doi. 10.1007/s00204-020-02820-4
By:
- Glaros, Trevor;
- Dhummakupt, Elizabeth S.;
- Rizzo, Gabrielle M.;
- McBride, Ethan;
- Carmany, Daniel O.;
- Wright, Linnzi K. M.;
- Forster, Jeffry S.;
- Renner, Julie A.;
- Moretz, Ruth W.;
- Dorsey, Russell;
- Marten, Mark R.;
- Huso, Walker;
- Doan, Alexander;
- Dorsey, Carrie D.;
- Phillips, Christopher;
- Benton, Bernard;
- Mach, Phillip M.
Publication type:
Article
Correction to: Mode of action-based risk assessment of genotoxic carcinogens.
Published in:
2020
By:
- Hartwig, Andrea;
- Arand, Michael;
- Epe, Bernd;
- Guth, Sabine;
- Jahnke, Gunnar;
- Lampen, Alfonso;
- Martus, Hans-Jörg;
- Monien, Bernhard;
- Rietjens, Ivonne M. C. M.;
- Schmitz-Spanke, Simone;
- Schriever-Schwemmer, Gerlinde;
- Steinberg, Pablo;
- Eisenbrand, Gerhard
Publication type:
Correction Notice
A putative AOP for pneumonia related to COVID-19.
Published in:
2020
By:
- Vinken, Mathieu
Publication type:
Letter
Construction of pioneering quantitative structure activity relationship screening models for abuse potential of designer drugs using index of ideality of correlation in monte carlo optimization.
Published in:
Archives of Toxicology, 2020, v. 94, n. 9, p. 3069, doi. 10.1007/s00204-020-02828-w
By:
- Kumar, Ashwani;
- Kumar, Parvin
Publication type:
Article
Highly sensitive retrospective determination of organophosphorous nerve agent biomarkers in human urine implemented in vivo in rabbit.
Published in:
Archives of Toxicology, 2020, v. 94, n. 9, p. 3033, doi. 10.1007/s00204-020-02827-x
By:
- Blanca, Merav;
- Shifrovitch, Avital;
- Dachir, Shlomit;
- Lazar, Shlomi;
- Elgarisi, Maor;
- Marder, Dana;
- Shamai Yamin, Tamar;
- Baranes, Shlomi;
- Avraham, Meir;
- Dekel Jaoui, Hani;
- Dagan, Shai;
- Weissberg, Avi
Publication type:
Article
Design and evaluation of bi-functional iron chelators for protection of dopaminergic neurons from toxicants.
Published in:
Archives of Toxicology, 2020, v. 94, n. 9, p. 3105, doi. 10.1007/s00204-020-02826-y
By:
- Gutbier, Simon;
- Kyriakou, Sotiris;
- Schildknecht, Stefan;
- Ückert, Anna-Katharina;
- Brüll, Markus;
- Lewis, Frank;
- Dickens, David;
- Pearson, Liam;
- Elson, Joanna L.;
- Michel, Sylvia;
- Hubscher-Bruder, Véronique;
- Brandel, Jeremy;
- Tetard, David;
- Leist, Marcel;
- Pienaar, Ilse S.
Publication type:
Article
Following the adverse outcome pathway from micronucleus to cancer using H2B-eGFP transgenic healthy stem cells.
Published in:
Archives of Toxicology, 2020, v. 94, n. 9, p. 3265, doi. 10.1007/s00204-020-02821-3
By:
- Hölzel, Bastian Niklas;
- Pfannkuche, Kurt;
- Allner, Bernhard;
- Allner, Hans Thomas;
- Hescheler, Jürgen;
- Derichsweiler, Daniel;
- Hollert, Henner;
- Schiwy, Andreas;
- Brendt, Julia;
- Schaffeld, Michael;
- Froschauer, Alexander;
- Stahlschmidt-Allner, Petra
Publication type:
Article
Ochratoxin A induces epithelial-to-mesenchymal transition and renal fibrosis through TGF-β/Smad2/3 and Wnt1/β-catenin signaling pathways in vitro and in vivo.
Published in:
Archives of Toxicology, 2020, v. 94, n. 9, p. 3329, doi. 10.1007/s00204-020-02829-9
By:
- Pyo, Min Cheol;
- Chae, Seung A.;
- Yoo, Hee Joon;
- Lee, Kwang-Won
Publication type:
Article
Cytotoxicity of fractured quartz on THP-1 human macrophages: role of the membranolytic activity of quartz and phagolysosome destabilization.
Published in:
Archives of Toxicology, 2020, v. 94, n. 9, p. 2981, doi. 10.1007/s00204-020-02819-x
By:
- Leinardi, Riccardo;
- Pavan, Cristina;
- Yedavally, Harita;
- Tomatis, Maura;
- Salvati, Anna;
- Turci, Francesco
Publication type:
Article
Interactions of antileukemic drugs with daunorubicin reductases: could reductases affect the clinical efficacy of daunorubicin chemoregimens?
Published in:
Archives of Toxicology, 2020, v. 94, n. 9, p. 3059, doi. 10.1007/s00204-020-02818-y
By:
- Novotná, Eva;
- Morell, Anselm;
- Büküm, Neslihan;
- Hofman, Jakub;
- Danielisová, Petra;
- Wsól, Vladimír
Publication type:
Article
The food contaminant, deoxynivalenol, modulates the Thelper/Treg balance and increases inflammatory bowel diseases.
Published in:
Archives of Toxicology, 2020, v. 94, n. 9, p. 3173, doi. 10.1007/s00204-020-02817-z
By:
- Payros, Delphine;
- Ménard, Sandrine;
- Laffitte, Joelle;
- Neves, Manon;
- Tremblay-Franco, Marie;
- Luo, Su;
- Fouche, Edwin;
- Snini, Selma P.;
- Theodorou, Vassilia;
- Pinton, Philippe;
- Oswald, Isabelle P.
Publication type:
Article
Synergistic effects of Bcl-2 inhibitors with AZD9291 on overcoming the acquired resistance of AZD9291 in H1975 cells.
Published in:
Archives of Toxicology, 2020, v. 94, n. 9, p. 3125, doi. 10.1007/s00204-020-02816-0
By:
- Liu, Zhongwei;
- Gao, Weimin
Publication type:
Article
Perfluorooctanoic acid (PFOA), perfluorooctane sulfonic acid (PFOS), and perfluorononanoic acid (PFNA) increase triglyceride levels and decrease cholesterogenic gene expression in human HepaRG liver cells.
Published in:
Archives of Toxicology, 2020, v. 94, n. 9, p. 3137, doi. 10.1007/s00204-020-02808-0
By:
- Louisse, Jochem;
- Rijkers, Deborah;
- Stoopen, Geert;
- Janssen, Aafke;
- Staats, Martijn;
- Hoogenboom, Ron;
- Kersten, Sander;
- Peijnenburg, Ad
Publication type:
Article
Triphenyl phosphate is a selective PPARγ modulator that does not induce brite adipogenesis in vitro and in vivo.
Published in:
Archives of Toxicology, 2020, v. 94, n. 9, p. 3087, doi. 10.1007/s00204-020-02815-1
By:
- Kim, Stephanie;
- Rabhi, Nabil;
- Blum, Benjamin C.;
- Hekman, Ryan;
- Wynne, Kieran;
- Emili, Andrew;
- Farmer, Stephen;
- Schlezinger, Jennifer J.
Publication type:
Article
Influence of breast cancer risk factors and intramammary biotransformation on estrogen homeostasis in the human breast.
Published in:
Archives of Toxicology, 2020, v. 94, n. 9, p. 3013, doi. 10.1007/s00204-020-02807-1
By:
- Pemp, Daniela;
- Geppert, Leo N.;
- Wigmann, Claudia;
- Kleider, Carolin;
- Hauptstein, René;
- Schmalbach, Katja;
- Ickstadt, Katja;
- Esch, Harald L.;
- Lehmann, Leane
Publication type:
Article
Brain alterations in GABA, glutamate and glutamine markers after chronic atrazine exposure in the male albino rat.
Published in:
Archives of Toxicology, 2020, v. 94, n. 9, p. 3217, doi. 10.1007/s00204-020-02806-2
By:
- Chávez-Pichardo, M. E.;
- Reyes-Bravo, D. Y.;
- Mendoza-Trejo, M. S.;
- Marín-López, A. G.;
- Giordano, M.;
- Hernández-Chan, N.;
- Domínguez-Marchan, K.;
- Ortega-Rosales, L. C.;
- Rodríguez, V. M.
Publication type:
Article
Revisiting the evidence for genotoxicity of acrylamide (AA), key to risk assessment of dietary AA exposure.
Published in:
Archives of Toxicology, 2020, v. 94, n. 9, p. 2939, doi. 10.1007/s00204-020-02794-3
By:
- Eisenbrand, Gerhard
Publication type:
Article
A comparison of thyroidal protection by stable iodine or perchlorate in the case of acute or prolonged radioiodine exposure.
Published in:
Archives of Toxicology, 2020, v. 94, n. 9, p. 3231, doi. 10.1007/s00204-020-02809-z
By:
- Eder, Stefan;
- Hermann, Cornelius;
- Lamkowski, Andreas;
- Kinoshita, Manabu;
- Yamamoto, Tetsuo;
- Abend, Michael;
- Shinomiya, Nariyoshi;
- Port, Matthias;
- Rump, Alexis
Publication type:
Article
Optimum concentration–response curve metrics for supervised selection of discriminative cellular phenotypic endpoints for chemical hazard assessment.
Published in:
Archives of Toxicology, 2020, v. 94, n. 9, p. 2951, doi. 10.1007/s00204-020-02813-3
By:
- Miller, James Alastair;
- Loo, Lit-Hsin
Publication type:
Article
Copper-dependent biological effects of particulate matter produced by brake systems on lung alveolar cells.
Published in:
Archives of Toxicology, 2020, v. 94, n. 9, p. 2965, doi. 10.1007/s00204-020-02812-4
By:
- Figliuzzi, Marina;
- Tironi, Matteo;
- Longaretti, Lorena;
- Mancini, Alessandro;
- Teoldi, Federico;
- Sangalli, Fabio;
- Remuzzi, Andrea
Publication type:
Article
Targeting organophosphorus compounds poisoning by novel quinuclidine-3 oximes: development of butyrylcholinesterase-based bioscavengers.
Published in:
Archives of Toxicology, 2020, v. 94, n. 9, p. 3157, doi. 10.1007/s00204-020-02811-5
By:
- Zandona, Antonio;
- Katalinić, Maja;
- Šinko, Goran;
- Radman Kastelic, Andreja;
- Primožič, Ines;
- Kovarik, Zrinka
Publication type:
Article
Impact of pesticide coexposure: an experimental study with binary mixtures of lambda-cyhalothrin (LCT) and captan and its impact on the toxicokinetics of LCT biomarkers of exposure.
Published in:
Archives of Toxicology, 2020, v. 94, n. 9, p. 3045, doi. 10.1007/s00204-020-02810-6
By:
- Bossou, Yélian Marc;
- Côté, Jonathan;
- Mantha, Marc;
- Haddad, Sami;
- Achard, Sophie;
- Bouchard, Michèle
Publication type:
Article
Interactions of polystyrene nanoplastics with in vitro models of the human intestinal barrier.
Published in:
Archives of Toxicology, 2020, v. 94, n. 9, p. 2997, doi. 10.1007/s00204-020-02805-3
By:
- Domenech, Josefa;
- Hernández, Alba;
- Rubio, Laura;
- Marcos, Ricard;
- Cortés, Constanza
Publication type:
Article
Neurotoxicity of Tityus bahiensis (brown scorpion) venom in sympathetic vas deferens preparations and neuronal cells.
Published in:
Archives of Toxicology, 2020, v. 94, n. 9, p. 3315, doi. 10.1007/s00204-020-02799-y
By:
- Collaço, Rita de Cássia;
- Hyslop, Stephen;
- Rocha, Thalita;
- Dorce, Valquiria A. C.;
- Rowan, Edward G.;
- Antunes, Edson
Publication type:
Article
Monocrotaline-induced liver toxicity in rat predicted by a combined in vitro physiologically based kinetic modeling approach.
Published in:
Archives of Toxicology, 2020, v. 94, n. 9, p. 3281, doi. 10.1007/s00204-020-02798-z
By:
- Suparmi, Suparmi;
- Wesseling, Sebastiaan;
- Rietjens, Ivonne M. C. M.
Publication type:
Article
Intrauterine RAS programming alteration-mediated susceptibility and heritability of temporal lobe epilepsy in male offspring rats induced by prenatal dexamethasone exposure.
Published in:
Archives of Toxicology, 2020, v. 94, n. 9, p. 3201, doi. 10.1007/s00204-020-02796-1
By:
- Hu, Shuwei;
- Yi, Yiwen;
- Jiang, Tao;
- Jiao, Zhexiao;
- Dai, Shiyun;
- Gong, Xiaohan;
- Li, Ke;
- Wang, Hui;
- Xu, Dan
Publication type:
Article
Human multidrug resistance protein 4 (MRP4) is a cellular efflux transporter for paracetamol glutathione and cysteine conjugates.
Published in:
Archives of Toxicology, 2020, v. 94, n. 9, p. 3027, doi. 10.1007/s00204-020-02793-4
By:
- Koenderink, Jan B.;
- van den Heuvel, Jeroen J. M. W.;
- Bilos, Ab;
- Vredenburg, Galvin;
- Vermeulen, Nico P. E.;
- Russel, Frans G. M.
Publication type:
Article
In vitro assessment of farnesoid X receptor antagonism to predict drug-induced liver injury risk.
Published in:
Archives of Toxicology, 2020, v. 94, n. 9, p. 3185, doi. 10.1007/s00204-020-02804-4
By:
- Norona, Leah M.;
- Fullerton, Aaron;
- Lawson, Chris;
- Leung, Leslie;
- Brumm, Jochen;
- Kiyota, Tomomi;
- Maher, Jonathan;
- Khojasteh, Cyrus;
- Proctor, William R.
Publication type:
Article
The mycotoxin deoxynivalenol activates GABAergic neurons in the reward system and inhibits feeding and maternal behaviours.
Published in:
Archives of Toxicology, 2020, v. 94, n. 9, p. 3297, doi. 10.1007/s00204-020-02791-6
By:
- Csikós, Vivien;
- Varró, Petra;
- Bódi, Veronika;
- Oláh, Szilvia;
- Világi, Ildikó;
- Dobolyi, Arpád
Publication type:
Article
Autophagy: a promising process for the treatment of acetaminophen-induced liver injury.
Published in:
Archives of Toxicology, 2020, v. 94, n. 9, p. 2925, doi. 10.1007/s00204-020-02780-9
By:
- Tan, Qiuhua;
- Liu, Yongjian;
- Deng, Xiaoyi;
- Chen, Jiajia;
- Tsai, Ping-Ju;
- Chen, Pei-Hsuan;
- Ye, Manxiang;
- Guo, Jiao;
- Su, Zhengquan
Publication type:
Article