Impact of testosterone, estradiol and age on stress urinary incontinence.

Siddle, Nicholas; Versi, Eboo

We suggest that this might equally apply to striated urethral muscle loss and that androgen therapy should be investigated in the treatment of SUI. Dear Editors, Van Geelen and Sand [[1]] have published an elegant and comprehensive review of urethral anatomy, function and the role of sex hormones. Study of sarcopenia in general suggests a major contribution of hormone lack and whereas estrogens prevent muscle apoptosis, androgens stimulate muscle growth and fiber hypertrophy [[5]].

URINARY stress incontinence; ESTRADIOL; TESTOSTERONE; STRIATED muscle

International Urogynecology Journal, 2023, Vol 34, Issue 9, p2333

0937-3462

Academic Journal

10.1007/s00192-023-05581-7