Psychopharmakologie autistischer Störungen.

Poustka, L.; Banaschewski, T.; Poustka, F.

utism spectrum disorders (ASD) are persistent, heterogeneous conditions that display many comorbid problems. Especially maladaptive behaviours like increased irritability, aggression, impulsivity and self-injurious behaviours are perceived as enormously stressful and can interfere with interventions targeting social and communication deficits. Medication treatments focussing on troubling comorbid problems in ASD can be fundamentally ameliorative, although core features of the disorder itself cannot be sufficiently treated. While atypical antipsychotics and stimulant medication have been proven to be effective in large multisite networks of ASD, serotonin reuptake inhibitors are of limited efficacy. Novel pharmacotherapies to improve social impairment are in the early stages of research.

AUTISM spectrum disorders; COMORBIDITY; IRRITABILITY (Psychology); AGGRESSION (Psychology); IMPULSIVE personality; SELF-injurious behavior; SOCIAL disabilities; COMMUNICATIVE disorders

Der Nervenarzt, 2011, Vol 82, Issue 5, p582

0028-2804

Academic Journal

10.1007/s00115-010-3238-7