Works matching AU LENZEN, Sigurd
Results: 67
Pancreas Pathology of Latent Autoimmune Diabetes in Adults (LADA) in Patients and in a LADA Rat Model Compared With Type 1 Diabetes.
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- 2020
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- journal article
Animal models of human type 1 diabetes for evaluating combination therapies and successful translation to the patient with type 1 diabetes.
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- 2017
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- journal article
MCPIP1 regulates the sensitivity of pancreatic beta-cells to cytokine toxicity.
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- Cell Death & Disease, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41419-018-1268-4
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- Article
Cytotoxicity and activation of the Wnt/beta-catenin pathway in mouse embryonic stem cells treated with four GSK3 inhibitors.
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- BMC Research Notes, 2014, v. 7, n. 1, p. 1, doi. 10.1186/1756-0500-7-273
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- Article
Remission of autoimmune diabetes by anti-TCR combination therapies with anti-IL-17A or/and anti-IL-6 in the IDDM rat model of type 1 diabetes.
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- 2020
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- journal article
ERO1-independent production of H<sub>2</sub>O<sub>2</sub> within the endoplasmic reticulum fuels Prdx4-mediated oxidative protein folding.
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- Journal of Cell Biology, 2015, v. 211, n. 2, p. 253, doi. 10.1083/jcb.201506123
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- Article
Effects of polyinosinic-polycytidylic acid and adoptive transfer of immune cells in the LEW.1AR1-iddm rat and in its coisogenic LEW. 1AR1 background strain.
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- Autoimmunity, 2005, v. 38, n. 4, p. 265, doi. 10.1080/08916930500114321
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- Article
Susceptibility of brown adipocytes to pro-inflammatory cytokine toxicity and reactive oxygen species.
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- Bioscience Reports, 2016, v. 36, n. 2, p. 1, doi. 10.1042/BSR20150193
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- Article
Combination of biotransformation and chromatography for the isolation and purification of mannoheptulose.
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- Biotechnology Journal, 2007, v. 2, n. 6, p. 692, doi. 10.1002/biot.200700004
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- Article
Monoamine Oxidase in Rat and Bovine Endocrine.
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- Journal of Neurochemistry, 1987, v. 49, n. 4, p. 1183, doi. 10.1111/j.1471-4159.1987.tb10009.x
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- Article
Peroxisome-Generated Hydrogen Peroxide as Important Mediator of Lipotoxicity in Insulin-Producing Cells.
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- Diabetes, 2011, v. 60, n. 1, p. 200, doi. 10.2337/db09-1401
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- Article
Impaired Glucose-Stimulated Insulin Secretion Is Coupled With Exocrine Pancreatic Lesions in the Cohen Diabetic Rat.
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- Diabetes, 2008, v. 57, n. 2, p. 279, doi. 10.2337/db07-0520
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- Article
Novel Insights Into the Regulation of the Bound and Diffusible Glucokinase in MIN6 β-Cells.
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- Diabetes, 2007, v. 56, n. 5, p. 1305, doi. 10.2337/db06-0894
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- Article
Mechanisms of Pancreatic Β-cell Death in Type 1 and Type 2 Diabetes.
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- Diabetes, 2005, v. 54, p. S97, doi. 10.2337/diabetes.54.suppl_2.S97
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- Article
Interaction of glucokinase with the liver regulatory protein is conferred by leucine-asparagine motifs of the enzyme.
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- 2005
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- Publication type:
- journal article
Immune cell infiltration, cytokine expression, and beta-cell apoptosis during the development of type 1 diabetes in the spontaneously diabetic LEW.1AR1/Ztm-iddm rat.
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- 2005
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- Publication type:
- journal article
Immune Cell Infiltration, Cytokine Expression, and β-Cell Apoptosis During the Development of Type 1 Diabetes in the Spontaneously Diabetic LEW.1AR1/Ztm-iddm Rat.
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- Diabetes, 2005, v. 54, n. 7, p. 2041, doi. 10.2337/diabetes.54.7.2041
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- Article
Mitochondrial catalase overexpression protects insulin-producing cells against toxicity of reactive oxygen species and proinflammatory cytokines.
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- 2004
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- Publication type:
- journal article
Interaction of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/FBPase-2) with glucokinase activates glucose phosphorylation and glucose metabolism in insulin-producing cells.
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- 2004
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- journal article
Improvement of the mitochondrial antioxidant defense status prevents cytokine-induced nuclear factor-kappaB activation in insulin-producing cells.
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- 2003
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- journal article
Protection of insulin-producing RINm5F cells against cytokine-mediated toxicity through overexpression of antioxidant enzymes.
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- 2000
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- journal article
Metabolic regulation, activity state, and intracellular binding of glucokinase in insulin-secreting cells.
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- 1999
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- journal article
Complementary action of antioxidant enzymes in the protection of bioengineered insulin-producing RINm5F cells against the toxicity of reactive oxygen species.
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- 1998
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- journal article
Relation between antioxidant enzyme gene expression and antioxidative defense status of insulin-producing cells.
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- 1997
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- journal article
Effects of IP3, spermine, and Mg2+ on regulation of Ca2+ transport by endoplasmic reticulum and mitochondria in permeabilized pancreatic islets.
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- 1991
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- Publication type:
- journal article
The role of lipid droplet formation in the protection of unsaturated fatty acids against palmitic acid induced lipotoxicity to rat insulin-producing cells.
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- Nutrition & Metabolism, 2016, v. 13, p. 1, doi. 10.1186/s12986-016-0076-z
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- Article
The pro-radical hydrogen peroxide as a stable hydroxyl radical distributor: lessons from pancreatic beta cells.
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- Archives of Toxicology, 2022, v. 96, n. 7, p. 1915, doi. 10.1007/s00204-022-03282-6
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- Article
The ubiquitin-proteasome system regulates the stability and activity of the glucose sensor glucokinase in pancreatic ß-cells.
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- Biochemical Journal, 2013, v. 456, n. 2, p. 173, doi. 10.1042/BJ20130262
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- Article
Effects of the novel mitochondrial protein mimitin in insulin-secreting cells.
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- Biochemical Journal, 2012, v. 446, n. 1, p. 349, doi. 10.1042/BJ20111920
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- Article
Effects of the novel mitochondrial protein mimitin in insulin-secreting cells.
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- Biochemical Journal, 2012, v. 445, n. 3, p. 349, doi. 10.1042/BJ20111920
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- Article
Antagonism Between Saturated and Unsaturated Fatty Acids in ROS Mediated Lipotoxicity in Rat Insulin-Producing Cells.
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- Cellular Physiology & Biochemistry (Karger AG), 2015, v. 36, n. 3, p. 852, doi. 10.1159/000430261
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- Article
Dimer interface rearrangement of the 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase rat liver isoenzyme by cAMP-dependent Ser-32 phosphorylation
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- FEBS Letters, 2012, v. 586, n. 10, p. 1419, doi. 10.1016/j.febslet.2012.03.066
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- Article
The Immediate Insulin-secretory Response of the Rat Pancreas to Glucose Compared with Tolbutamide and Other Secretagogues.
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- Diabetes, 1978, v. 27, n. 1, p. 27, doi. 10.2337/diab.27.1.27
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- Article
TriPer, an optical probe tuned to the endoplasmic reticulum tracks changes in luminal H<sub>2</sub>O<sub>2</sub>.
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- BMC Biology, 2017, v. 15, p. 1, doi. 10.1186/s12915-017-0367-5
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- Article
Reversal of Diabetes Through Gene Therapy of Diabetic Rats by Hepatic Insulin Expression via Lentiviral Transduction.
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- Molecular Therapy, 2012, v. 20, n. 5, p. 918, doi. 10.1038/mt.2012.8
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- Article
Insulin-producing Surrogate β-cells From Embryonic Stem Cells: Are We There Yet?
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- Molecular Therapy, 2011, v. 19, n. 10, p. 1759, doi. 10.1038/mt.2011.165
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- Article
Mechanisms of lipotoxicity‐induced dysfunction and death of human pancreatic beta cells under obesity and type 2 diabetes conditions.
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- Obesity Reviews, 2024, v. 25, n. 5, p. 1, doi. 10.1111/obr.13703
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- Article
Advanced Glycation End-Products (AGEs) of Lysine and Effects of Anti-TCR/Anti-TNF-α Antibody-Based Therapy in the LEW.1AR1 -iddm Rat, an Animal Model of Human Type 1 Diabetes.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 3, p. 1541, doi. 10.3390/ijms23031541
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- Article
Changes in gene expression and morphology of mouse embryonic stem cells on differentiation into insulin-producing cells in vitro and in vivo.
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- Diabetes/Metabolism Research & Reviews, 2009, v. 25, n. 5, p. 464, doi. 10.1002/dmrr.965
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- Article
Prevention of insulin resistance and beta-cell loss by abrogating PKCε-induced serine phosphorylation of muscle IRS-1 in Psammomys obesus.
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- Diabetes/Metabolism Research & Reviews, 2008, v. 24, n. 7, p. 577, doi. 10.1002/dmrr.881
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- Article
Prevention of nutritionally induced diabetes by rosiglitazone in the gerbil Psammomys obesus.
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- Diabetes/Metabolism Research & Reviews, 2006, v. 22, n. 2, p. 139, doi. 10.1002/dmrr.583
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- Article
Light-induced intracellular hydrogen peroxide generation through genetically encoded photosensitizer KillerRed-SOD1.
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- Free Radical Research, 2018, v. 52, n. 10, p. 1170, doi. 10.1080/10715762.2018.1540042
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- Article
Dynamics of Insulin Secretion from EndoC-βH1 β-Cell Pseudoislets in Response to Glucose and Other Nutrient and Nonnutrient Secretagogues.
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- Journal of Diabetes Research, 2017, p. 1, doi. 10.1155/2017/2309630
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- Article
Lipid composition of glucose-stimulated pancreatic islets and insulin-secreting tumor cells.
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- Lipids, 1994, v. 29, n. 10, p. 685, doi. 10.1007/BF02538912
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- Article
The mutation of the LEW.1AR1- iddm rat maps to the telomeric end of rat chromosome 1.
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- Mammalian Genome, 2008, v. 19, n. 4, p. 292, doi. 10.1007/s00335-008-9102-4
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- Article
Genetic analysis of the LEW.1AR1- iddm rat: an animal model for spontaneous diabetes mellitus.
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- Mammalian Genome, 2005, v. 16, n. 6, p. 432, doi. 10.1007/s00335-004-3022-8
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- Article
Anti-TCR therapy combined with fingolimod for reversal of diabetic hyperglycemia by β cell regeneration in the LEW.1AR1- iddm rat model of type 1 diabetes.
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- Journal of Molecular Medicine, 2014, v. 92, n. 7, p. 743, doi. 10.1007/s00109-014-1137-2
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- Article
Cytokine toxicity in insulin-producing cells is mediated by nitro-oxidative stress-induced hydroxyl radical formation in mitochondria.
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- Journal of Molecular Medicine, 2011, v. 89, n. 8, p. 785, doi. 10.1007/s00109-011-0747-1
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- Article
Asymmetric dimethylation and citrullination in the LEW.1AR1-iddm rat, an animal model of human type 1 diabetes, and effects of anti-TCR/anti-TNF-α antibody-based therapy.
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- Amino Acids, 2020, v. 52, n. 1, p. 103, doi. 10.1007/s00726-019-02811-5
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- Article
Results, meta-analysis and a first evaluation of U<sub>NOx</sub>R, the urinary nitrate-to-nitrite molar ratio, as a measure of nitrite reabsorption in experimental and clinical settings.
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- Amino Acids, 2018, v. 50, n. 7, p. 799, doi. 10.1007/s00726-018-2573-z
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- Article