Works matching DE "DEMETHYLASE"

Results: 519

RSV‐Induced Regulation of DC via H3K4 Demethylase KDM5b.

Published in:

European Journal of Immunology, 2025, v. 55, n. 5, p. 1, doi. 10.1002/eji.202451309

By:

Mire, Mohamed M.;
Martinez, Llilian A.;
Cortes, Ashley M.;
Morris, Susan;
Rasky, Andrew;
Ptaschinski, Catherine;
Lukacs, Nicholas W.

Publication type:

Article

JMJD1C demethylates MDC1 to regulate the RNF8 and BRCA1-mediated chromatin response to DNA breaks.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 12, p. 1425, doi. 10.1038/nsmb.2702

By:

Watanabe, Sugiko;
Watanabe, Kenji;
Akimov, Vyacheslav;
Bartkova, Jirina;
Blagoev, Blagoy;
Lukas, Jiri;
Bartek, Jiri

Publication type:

Article

A mediator methylation mystery: JMJD1C demethylates MDC1 to regulate DNA repair.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 12, p. 1346, doi. 10.1038/nsmb.2729

By:

Lu, Jian;
Matunis, Michael J

Publication type:

Article

Polycomb PHF19 binds H3K36me3 and recruits PRC2 and demethylase NO66 to embryonic stem cell genes during differentiation.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 12, p. 1273, doi. 10.1038/nsmb.2449

By:

Brien, Gerard L;
Gambero, Guillermo;
O'Connell, David J;
Jerman, Emilia;
Turner, Siobhán A;
Egan, Chris M;
Dunne, Eiseart J;
Jurgens, Maike C;
Wynne, Kieran;
Piao, Lianhua;
Lohan, Amanda J;
Ferguson, Neil;
Shi, Xiaobing;
Sinha, Krishna M;
Loftus, Brendan J;
Cagney, Gerard;
Bracken, Adrian P

Publication type:

Article

JARID1‐targeted histone H3 demethylase inhibitors exhibit anti‐proliferative activity and overcome cisplatin resistance in canine oral melanoma cell lines.

Published in:

Veterinary & Comparative Oncology, 2021, v. 19, n. 3, p. 518, doi. 10.1111/vco.12691

By:

Tobin, Savannah J.;
Chang, Hong;
Kent, Michael S.;
Davies, Alexander E.

Publication type:

Article

Dioxygen Binding Is Controlled by the Protein Environment in Non‐heme FeII and 2‐Oxoglutarate Oxygenases: A Study on Histone Demethylase PHF8 and an Ethylene‐Forming Enzyme.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 24, p. 1, doi. 10.1002/chem.202300138

By:

Chaturvedi, Shobhit S.;
Thomas, Midhun George;
Bathir Jaber Sathik Rifayee, Simahudeen;
White, Walter;
Wildey, Jon;
Warner, Cait;
Schofield, Christopher J.;
Hu, Jian;
Hausinger, Robert P.;
Karabencheva‐Christova, Tatayana G.;
Christov, Christo Z.

Publication type:

Article

Front Cover: Dioxygen Binding Is Controlled by the Protein Environment in Non‐heme FeII and 2‐Oxoglutarate Oxygenases: A Study on Histone Demethylase PHF8 and an Ethylene‐Forming Enzyme (Chem. Eur. J. 24/2023).

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 24, p. 1, doi. 10.1002/chem.202300138

By:

Chaturvedi, Shobhit S.;
Thomas, Midhun George;
Rifayee, Simahudeen Bathir Jaber Sathik;
White, Walter;
Wildey, Jon;
Warner, Cait;
Schofield, Christopher J.;
Hu, Jian;
Hausinger, Robert P.;
Karabencheva‐Christova, Tatayana G.;
Christov, Christo Z.

Publication type:

Article

Dioxygen Binding Is Controlled by the Protein Environment in Non‐heme FeII and 2‐Oxoglutarate Oxygenases: A Study on Histone Demethylase PHF8 and an Ethylene‐Forming Enzyme.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 24, p. 1, doi. 10.1002/chem.202300138

By:

Chaturvedi, Shobhit S.;
Thomas, Midhun George;
Rifayee, Simahudeen Bathir Jaber Sathik;
White, Walter;
Wildey, Jon;
Warner, Cait;
Schofield, Christopher J.;
Hu, Jian;
Hausinger, Robert P.;
Karabencheva‐Christova, Tatayana G.;
Christov, Christo Z.

Publication type:

Article

What Is the Catalytic Mechanism of Enzymatic Histone N‐Methyl Arginine Demethylation and Can It Be Influenced by an External Electric Field?

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 46, p. 11750, doi. 10.1002/chem.202102158

By:

Ramanan, Rajeev;
Waheed, Sodiq O.;
Schofield, Christopher J.;
Christov, Christo Z.

Publication type:

Article

Switching Demethylation Activities between AlkB Family RNA/DNA Demethylases through Exchange of Active-Site Residues.

Published in:

Angewandte Chemie, 2014, v. 126, n. 14, p. 3733, doi. 10.1002/ange.201310050

By:

Zhu, Chenxu;
Yi, Chengqi

Publication type:

Article

Is JmjC Oxygenase Catalysis Limited to Demethylation?

Published in:

Angewandte Chemie, 2013, v. 125, n. 30, p. 7863, doi. 10.1002/ange.201303282

By:

Hopkinson, Richard J.;
Walport, Louise J.;
Münzel, Martin;
Rose, Nathan R.;
Smart, Tristan J.;
Kawamura, Akane;
Claridge, Timothy D. W.;
Schofield, Christopher J.

Publication type:

Article

RNA-based disease control as a complementary measure to fight Fusarium fungi through silencing of the azole target Cytochrome P450 Lanosterol C-14 α-Demethylase.

Published in:

European Journal of Plant Pathology, 2018, v. 152, n. 4, p. 1003, doi. 10.1007/s10658-018-1518-4

By:

Koch, Aline;
Stein, Elke;
Kogel, Karl-Heinz

Publication type:

Article

The re-expression of the epigenetically silenced e- cadherin gene by a polyamine analogue lysine-specific demethylase-1 (LSD1) inhibitor in human acute myeloid leukemia cell lines.

Published in:

Amino Acids, 2014, v. 46, n. 3, p. 585, doi. 10.1007/s00726-013-1485-1

By:

Murray-Stewart, Tracy;
Woster, Patrick;
Casero, Robert

Publication type:

Article

Identification of a novel signature based on RNA methylation-associated anoikis-related genes for predicting prognosis and characterizing immune landscape in colorectal cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-01964-y

By:

Zhu, Liye;
Qiu, Xinze;
Liang, Shengmei;
Huang, Shanpei;
Ning, Qiting;
Chen, Xingmei;
Chen, Ni;
Qin, longjie;
Huang, Jiean;
Liu, Shiquan

Publication type:

Article

Effect of cadmium, mercury, and zinc on the hepatic microsomal enzymes of Channa punctatus.

Published in:

Bulletin of Environmental Contamination & Toxicology, 1994, v. 52, n. 6, p. 893, doi. 10.1007/BF00200699

By:

Dalal, R.;
Bhattacharya, S.

Publication type:

Article

Modulation of microsomal membrane associated detoxication enzymes activity by methyl isocyanate (MIC) exposure.

Published in:

Bulletin of Environmental Contamination & Toxicology, 1991, v. 47, n. 5, p. 675, doi. 10.1007/BF01701133

By:

Mishra, Anil;
Dwivedi, Premendra;
Verma, Ashish;
Mishra, Jaya;
Sinha, M.;
Dutta, K.;
Ray, P.

Publication type:

Article

Effect of diisopropyl fluorophosphate on hepatic microsomal systems in two strains of rats.

Published in:

Bulletin of Environmental Contamination & Toxicology, 1990, v. 44, n. 6, p. 924, doi. 10.1007/BF01702185

By:

Meneguz, A.;
Michalek, H.

Publication type:

Article

Using the scoparone O-demethylase assay for categorizing types of hepatic microsomal monooxygenase inducers.

Published in:

Bulletin of Environmental Contamination & Toxicology, 1989, v. 42, n. 4, p. 489, doi. 10.1007/BF01700226

By:

Kato, Sachiko;
Yamamoto, Kenji

Publication type:

Article

Profile of drug metabolizing enzymes in rats treated with parathion, malathion, and phosalone under various conditions of protein energy malnutrition.

Published in:

Bulletin of Environmental Contamination & Toxicology, 1988, v. 40, n. 1, p. 110, doi. 10.1007/BF01689396

By:

Bulusu, Saraswati;
Chakravarty, Indira

Publication type:

Article

FTO GENE VARIANTS AND CONSUMPTION OF ALCOHOLIC BEVERAGES.

Published in:

Alcoholism & Drug Addiction / Alkoholizm i Narkomania, 2020, v. 33, n. 4, p. 341, doi. 10.5114/ain.2020.104816

By:

Flaga, Anna Karolina;
Mach, Anna;
Gromadzka, Grażyna

Publication type:

Article

Gene Regulation and Mitochondrial Activity During White and Brown Adipogenesis Are Modulated by KDM5 Histone Demethylase.

Published in:

Journal of the Endocrine Society, 2024, v. 8, n. 4, p. 1, doi. 10.1210/jendso/bvae029

By:

Vergnes, Laurent;
Wiese, Carrie B;
Zore, Temeka;
Riestenberg, Carrie;
Avetisyan, Rozeta;
Reue, Karen

Publication type:

Article

Influences of lysine‐specific demethylase 1 inhibitors on NO synthase–Kruppel‐like factor pathways in human endothelial cells in vitro and zebrafish (Danio rerio) larvae in vivo.

Published in:

Journal of Applied Toxicology, 2023, v. 43, n. 11, p. 1748, doi. 10.1002/jat.4512

By:

Yuan, Jialin;
Que, Ruiman;
Zhao, Weichao;
Song, Fengmei;
Cao, Yi;
Yu, Bin

Publication type:

Article

Histone demethylase JHDM2A regulates H3K9 dimethylation in response to arsenic‐induced DNA damage and repair in normal human liver cells.

Published in:

Journal of Applied Toxicology, 2021, v. 41, n. 4, p. 650, doi. 10.1002/jat.4142

By:

Zhang, An‐liu;
Tang, Shun‐fang;
Yang, Yue;
Li, Chang‐zhe;
Ding, Xue‐jiao;
Zhao, Hua;
Wang, Jun‐hua;
Yang, Guang‐hong;
Li, Jun

Publication type:

Article

NCL1, A Highly Selective Lysine-Specific Demethylase 1 Inhibitor, Suppresses Castration-Resistant Prostate Cancer Growth via Regulation of Apoptosis and Autophagy.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 4, p. 442, doi. 10.3390/jcm8040442

By:

Etani, Toshiki;
Naiki, Taku;
Naiki-Ito, Aya;
Suzuki, Takayoshi;
Iida, Keitaro;
Nozaki, Satoshi;
Kato, Hiroyuki;
Nagayasu, Yuko;
Suzuki, Shugo;
Kawai, Noriyasu;
Yasui, Takahiro;
Takahashi, Satoru

Publication type:

Article

Identification and Characterization of Fusarium fujikuroi Pathotypes Responsible for an Emerging Bakanae Disease of Rice in India.

Published in:

Plants (2223-7747), 2023, v. 12, n. 6, p. 1303, doi. 10.3390/plants12061303

By:

Tadasanahaller, Prashantha S.;
Bashyal, Bishnu Maya;
Yadav, Jagdish;
Krishnan Subbaiyan, Gopala;
Ellur, Ranjith K.;
Aggarwal, Rashmi

Publication type:

Article

Evolutionary History and Functional Diversification of the JmjC Domain-Containing Histone Demethylase Gene Family in Plants.

Published in:

Plants (2223-7747), 2022, v. 11, n. 8, p. N.PAG, doi. 10.3390/plants11081041

By:

Ma, Shifeng;
Zhang, Zhiqiang;
Long, Yingqiang;
Huo, Wenqi;
Zhang, Yuzhi;
Yang, Xiaoqing;
Zhang, Jie;
Li, Xinyang;
Du, Qiying;
Liu, Wei;
Yang, Daigang;
Ma, Xiongfeng

Publication type:

Article

Characterization and Stress Response of the JmjC Domain-Containing Histone Demethylase Gene Family in the Allotetraploid Cotton Species Gossypium hirsutum.

Published in:

Plants (2223-7747), 2020, v. 9, n. 11, p. 1617, doi. 10.3390/plants9111617

By:

Zhang, Jie;
Feng, Junping;
Liu, Wei;
Ren, Zhongying;
Zhao, Junjie;
Pei, Xiaoyu;
Liu, Yangai;
Yang, Daigang;
Ma, Xiongfeng

Publication type:

Article

Structure of the Arabidopsis JMJ14-H3K4me3 Complex Provides Insight into the Substrate Specificity of KDM5 Subfamily Histone Demethylases.

Published in:

Plant Cell, 2018, v. 30, n. 1, p. 167, doi. 10.1105/tpc.17.00666

By:

Yang, Zhenlin;
Qiu, Qi;
Chen, Wei;
Jia, Bei;
Chen, Xiaomei;
Hu, Hongmiao;
He, Kaixuan;
Deng, Xian;
Li, Sisi;
Tao, W. Andy;
Cao, Xiaofeng;
Du, Jiamu

Publication type:

Article

ALKBH10B Is an RNA N 6-Methyladenosine Demethylase Affecting Arabidopsis Floral Transition.

Published in:

Plant Cell, 2017, v. 29, n. 12, p. 2995, doi. 10.1105/tpc.16.00912

By:

Duan, Hong-Chao;
Wei, Lian-Huan;
Zhang, Chi;
Wang, Ye;
Chen, Lin;
Lu, Zhike;
Chen, Peng R.;
He, Chuan;
Jia, Guifang

Publication type:

Article

Mutations in the Arabidopsis H3K4me2/3 Demethylase JMJ14 Suppress Posttranscriptional Gene Silencing by Decreasing Transgene Transcription.

Published in:

Plant Cell, 2012, v. 24, n. 9, p. 3603, doi. 10.1105/tpc.112.103119

By:

Masson, Ivan Le;
Jauvion, Vincent;
Bouteiller, Nathalie;
Rivard, Maud;
Elmayan, Taline;
Vaucheret, Hervé

Publication type:

Article

The Lysine Demethylase KDM5B Regulates Islet Function and Glucose Homeostasis.

Published in:

Journal of Diabetes Research, 2019, p. 1, doi. 10.1155/2019/5451038

By:

Backe, Marie Balslev;
Jin, Chunyu;
Andreone, Luz;
Sankar, Aditya;
Agger, Karl;
Helin, Kristian;
Madsen, Andreas Nygaard;
Poulsen, Steen Seier;
Bysani, Madhusudhan;
Bacos, Karl;
Ling, Charlotte;
Perone, Marcelo Javier;
Holst, Birgitte;
Mandrup-Poulsen, Thomas

Publication type:

Article

Expression pattern of histone lysine-specific demethylase 6B in gastric cancer.

Published in:

Oncology Letters, 2021, v. 21, n. 6, p. N.PAG

By:

Wang, Shujun;
Wang, Yiping;
Zhu, Hui;
Chen, Miaohui;
Zhang, Liang

Publication type:

Article

Comparison of the expression levels of lysine-specific demethylase 1 and survival outcomes between triple-negative and non-triple-negative breast cancer.

Published in:

Oncology Letters, 2021, v. 21, n. 2, p. 1, doi. 10.3892/ol.2020.12363

By:

KANGRONG ZHAO;
YANLIN LI;
TIANTIAN HAN;
AIQIN SUN;
WENXUAN BIAN;
MINGYUE LI;
QIONG LIN;
GENBAO SHAO

Publication type:

Article

Downregulation of lysine-specific demethylase 1 enhances the sensitivity of hormone-sensitive prostate cancer cells to androgen deprivation therapy.

Published in:

Oncology Letters, 2021, v. 21, n. 2, p. 1, doi. 10.3892/ol.2020.12354

By:

MIN WANG;
XIUHENG LIU;
ZHIYUAN CHEN;
LU ZHANG;
XIAODONG WENG

Publication type:

Article

A potential common role of the Jumonji C domain-containing 1A histone demethylase and chromatin remodeler ATRX in promoting colon cancer.

Published in:

Oncology Letters, 2018, v. 16, n. 5, p. 6652, doi. 10.3892/ol.2018.9487

By:

Li, Xiaomeng;
Oh, Sangphil;
Song, Hoogeun;
Shin, Sook;
Zhang, Bin;
Freeman, Willard M.;
Janknecht, Ralf

Publication type:

Article

Emerging function of N6-methyladenosine in cancer.

Published in:

Oncology Letters, 2018, v. 16, n. 5, p. 5519, doi. 10.3892/ol.2018.9395

By:

Hong, Kwonho

Publication type:

Article

KDM3A is not associated with metastasis and prognosis of breast cancer.

Published in:

Oncology Letters, 2018, v. 15, n. 6, p. 9751, doi. 10.3892/ol.2018.8578

By:

Yao, Juan;
ZhENg, Shutao;
Li, Baiyan;
Li, Xinxin;
Liu, WENya

Publication type:

Article

Synthesis, Molecular Docking Studies, and Antifungal Activity Evaluation of New Benzimidazole-Triazoles as Potential Lanosterol 14α-Demethylase Inhibitors.

Published in:

Journal of Chemistry, 2017, p. 1, doi. 10.1155/2017/9387102

By:

Can, Nafiz Öncü;
Acar Çevik, Ulviye;
Sağlık, Begüm Nurpelin;
Levent, Serkan;
Korkut, Büşra;
Özkay, Yusuf;
Kaplancıklı, Zafer Asım;
Koparal, Ali Savaş

Publication type:

Article

A New Amino Acid Substitution at G150S in Lanosterol 14-α Demethylase（Erg11 protein）in Multi-azole-resistant Trichosporon asahii.

Published in:

Medical Mycology Journal, 2017, v. 58, n. 2, p. E23, doi. 10.3314/mmj.16-00027

By:

Hisako Kushima;
Issei Tokimatsu;
Hiroshi Ishii;
Rie Kawano;
Kentaro Watanabe;
Jun-ichi Kadota

Publication type:

Article

A New Amino Acid Substitution at G150S in Lanosterol 14-α Demethylase (Erg11 protein) in Multi-azole-resistant Trichosporon asahii.

Published in:

Medical Mycology Journal, 2017, v. 58, n. 1, p. E23, doi. 10.3314/mmj.16-00027

By:

Hisako Kushima;
Issei Tokimatsu;
Hiroshi Ishii;
Rie Kawano;
Kentaro Watanabe;
Jun-ichi Kadota

Publication type:

Article

Recent Acquisition of Functional m6A RNA Demethylase Domain in Orchid Ty3/Gypsy Elements.

Published in:

Frontiers in Plant Science, 2022, v. 13, p. 1, doi. 10.3389/fpls.2022.939843

By:

Alvarado-Marchena, Luis;
Martínez-Pérez, Mireya;
Aparicio, Frederic;
Pallas, Vicente;
Maumus, Florian

Publication type:

Article

ALKBH10B, an mRNA m6A Demethylase, Modulates ABA Response During Seed Germination in Arabidopsis.

Published in:

Frontiers in Plant Science, 2021, v. 12, p. 1, doi. 10.3389/fpls.2021.712713

By:

Tang, Jun;
Yang, Junbo;
Duan, Hongchao;
Jia, Guifang

Publication type:

Article

Two Arabidopsis Homologs of Human Lysine-Specific Demethylase Function in Epigenetic Regulation of Plant Defense Responses.

Published in:

Frontiers in Plant Science, 2021, v. 12, p. 1, doi. 10.3389/fpls.2021.688003

By:

Noh, Seong Woo;
Seo, Ri-Ra;
Park, Hee Jin;
Jung, Ho Won

Publication type:

Article

Genistein Ameliorates Renal Fibrosis Through Regulation Snail via m6A RNA Demethylase ALKBH5.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.579265

By:

Ning, Yichun;
Chen, Jing;
Shi, Yiqin;
Song, Nana;
Yu, Xiaofang;
Fang, Yi;
Ding, Xiaoqiang

Publication type:

Article

Cloning of a novel tetrahydrofolate-dependent dicamba demethylase gene from dicamba-degrading consortium and characterization of the gene product.

Published in:

Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.978577

By:

Na Li;
Le Chen;
Chen, E.;
Cansheng Yuan;
Hao Zhang;
Jian He

Publication type:

Article

Lysine-Specific Histone Demethylase 1A Regulates Macrophage Polarization and Checkpoint Molecules in the Tumor Microenvironment of Triple-Negative Breast Cancer.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.01351

By:

Tan, Abel H. Y.;
Tu, WenJuan;
McCuaig, Robert;
Hardy, Kristine;
Donovan, Thomasina;
Tsimbalyuk, Sofiya;
Forwood, Jade K.;
Rao, Sudha

Publication type:

Article

HMG20A is required for SNAI1-mediated epithelial to mesenchymal transition.

Published in:

Oncogene, 2015, v. 34, n. 41, p. 5264, doi. 10.1038/onc.2014.446

By:

Rivero, S;
Ceballos-Chávez, M;
Bhattacharya, S S;
Reyes, J C

Publication type:

Article

Lysine-specific demethylase 1 promotes the stemness and chemoresistance of Lgr5+ liver cancer initiating cells by suppressing negative regulators of β-catenin signaling.

Published in:

Oncogene, 2015, v. 34, n. 24, p. 3214, doi. 10.1038/onc.2015.182

By:

Lei, Z-J;
Wang, J;
Xiao, H-L;
Guo, Y;
Wang, T;
Li, Q;
Liu, L;
Luo, X;
Fan, L-L;
Lin, L;
Mao, C-Y;
Wang, S-N;
Wei, Y-L;
Lan, C-H;
Jiang, J;
Yang, X-J;
Liu, P-D;
Chen, D-F;
Wang, B

Publication type:

Article

Lysine-specific demethylase 1 promotes the stemness and chemoresistance of Lgr5+ liver cancer initiating cells by suppressing negative regulators of β-catenin signaling.

Published in:

Oncogene, 2015, v. 34, n. 24, p. 3188, doi. 10.1038/onc.2015.129

By:

Lei, Z-J;
Wang, J;
Xiao, H-L;
Guo, Y;
Wang, T;
Li, Q;
Liu, L;
Luo, X;
Fan, L-L;
Lin, L;
Mao, C-Y;
Wang, S-N;
Wei, Y-L;
Lan, C-H;
Jiang, J;
Yang, X-J;
Liu, P-D;
Chen, D-F;
Wang, B

Publication type:

Article

new demethylase gene, OsDML4, is involved in high temperature-increased grain chalkiness in rice.

Published in:

Journal of Experimental Botany, 2022, v. 73, n. 22, p. 7273, doi. 10.1093/jxb/erac367

By:

Yan, Yan;
Li, Chao;
Liu, Zhen;
Zhuang, Jun-Jie;
Kong, Jia-Rui;
Yang, Zhen-Kun;
Yu, Jie;
Alam, Mohammad Shah;
Ruan, Cheng-Cheng;
Zhang, Heng-Mu;
Xu, Jian-Hong

Publication type:

Article