Works matching AU Beal, M. Flint

Results: 216

Metabolomic profiling to develop blood biomarkers for Parkinson's disease.

Published in:

2008

By:

Bogdanov M;
Matson WR;
Wang L;
Matson T;
Saunders-Pullman R;
Bressman SS;
Flint Beal M;
Bogdanov, Mikhail;
Matson, Wayne R;
Wang, Lei;
Matson, Theodore;
Saunders-Pullman, Rachel;
Bressman, Susan S;
Flint Beal, M

Publication type:

journal article

Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid.

Published in:

Nature, 1986, v. 321, n. 6066, p. 168, doi. 10.1038/321168a0

By:

Beal, M. Flint;
Kowall, Neil W.;
Ellison, David W.;
Mazurek, Michael F.;
Swartz, Kenton J.;
Martin, Joseph B.

Publication type:

Article

High‐dose biotin restores redox balance, energy and lipid homeostasis, and axonal health in a model of adrenoleukodystrophy.

Published in:

Brain Pathology, 2020, v. 30, n. 5, p. 945, doi. 10.1111/bpa.12869

By:

Fourcade, Stéphane;
Goicoechea, Leire;
Parameswaran, Janani;
Schlüter, Agatha;
Launay, Nathalie;
Ruiz, Montserrat;
Seyer, Alexandre;
Colsch, Benoit;
Calingasan, Noel Ylagan;
Ferrer, Isidre;
Beal, M. Flint;
Sedel, Frédéric;
Pujol, Aurora

Publication type:

Article

The Role of Mitochondria in the Pathogenesis of Neurodegenerative Diseases.

Published in:

Brain Pathology, 2000, v. 10, n. 3, p. 462, doi. 10.1111/j.1750-3639.2000.tb00278.x

By:

Manfredim, Giovanni;
Beal, M. Flint

Publication type:

Article

Oxidative Stress in Huntington's Disease.

Published in:

Brain Pathology, 1999, v. 9, n. 1, p. 147, doi. 10.1111/j.1750-3639.1999.tb00216.x

By:

Browne, Susan E.;
Ferrante, Robert J.;
Beal, M. Flint

Publication type:

Article

Hugging tight in Huntington's.

Published in:

2011

By:

Johri, Ashu;
Chaturvedi, Rajnish K.;
Beal, M. Flint

Publication type:

Correction Notice

Hugging tight in Huntington's.

Published in:

Nature Medicine, 2011, v. 17, n. 3, p. 245, doi. 10.1038/nm0311-245

By:

Johri, Ashu;
Chaturvedi, Rajnish K.;
Beal, M. Flint

Publication type:

Article

Portal to Alzheimer's disease.

Published in:

Nature Medicine, 2008, v. 14, n. 10, p. 1020, doi. 10.1038/nm1008-1020

By:

Starkov, Anatoly A;
Beal, Flint M

Publication type:

Article

Merging mitochondria for neuronal survival.

Published in:

Nature Medicine, 2007, v. 13, n. 10, p. 1140, doi. 10.1038/nm1007-1140

By:

Manfredi, Giovanni;
Beal, M. Flint

Publication type:

Article

Corrigendum: Functional engraftment of human ES cell–derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes.

Published in:

2007

By:

Roy, Neeta S.;
Cleren, Carine;
Singh, Shashi K.;
Lichuan Yang;
Beal, M. Flint;
Goldman, Steven A.

Publication type:

Correction Notice

Large stem cell grafts could lead to erroneous interpretations of behavioral results?

Published in:

2007

By:

Goldman, Steven A.;
Roy, Neeta S.;
Beal, M. Flint;
Cleren, Carine

Publication type:

Letter

Alzheimer's APP mangles mitochondria.

Published in:

Nature Medicine, 2006, v. 12, n. 11, p. 1241, doi. 10.1038/nm1106-1241

By:

Lin, Michael T.;
Beal, M. Flint

Publication type:

Article

Functional engraftment of human ES cell–derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes.

Published in:

Nature Medicine, 2006, v. 12, n. 11, p. 1259, doi. 10.1038/nm1495

By:

Roy, Neeta S.;
Cleren, Carine;
Singh, Shashi K.;
Yang, Lichuan;
Beal, M. Flint;
Goldman, Steven A.

Publication type:

Article

\Less stress, longer life.

Published in:

Nature Medicine, 2005, v. 11, n. 6, p. 598, doi. 10.1038/nm0605-598

By:

Beal, M. Flint

Publication type:

Article

NOS knockouts and neuroprotection.

Published in:

Nature Medicine, 1999, v. 5, n. 12, p. 1354

By:

Grünewald, Thomas;
Beal, M. Flint

Publication type:

Article

Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis.

Published in:

Nature Medicine, 1999, v. 5, n. 3, p. 347, doi. 10.1038/6568

By:

Klivenyi, Peter;
Ferrante, Robert J.;
Matthews, Russell T.;
Bogdanov, Mikhail B.;
Klein, Autumn M.;
Andreassen, Ole A.;
Mueller, Gerald;
Wermer, Marieke;
Kaddurah-Daouk, Rima;
Beal, M. Flint

Publication type:

Article

Galanin-Like Immunoreactivity Is Unchanged in Alzheimer's Disease and Parkinson's Disease Dementia Cerebral Cortex.

Published in:

Journal of Neurochemistry, 1988, v. 51, n. 6, p. 1935, doi. 10.1111/j.1471-4159.1988.tb01181.x

By:

Beal, M. Flint;
Clevens, Ross A.;
Chattha, Geetinder K.;
MacGarvey, Usha M.;
Mazurek, Michael F.;
Gabriel, Steven M.

Publication type:

Article

Somatostatin Binding Sites in Human and Monkey Brain: Localization and Characterization.

Published in:

Journal of Neurochemistry, 1986, v. 46, n. 2, p. 359, doi. 10.1111/j.1471-4159.1986.tb12976.x

By:

Beal, M. Flint;
Tran, Vinh T.;
Mazurek, Michael F.;
Chattha, Geetinder;
Martin, Joseph B.

Publication type:

Article

Prospects for neuroprotective therapies in prodromal Huntington's disease.

Published in:

2014

By:

Chandra, Abhishek;
Johri, Ashu;
Beal, M Flint

Publication type:

journal article

Prospects for neuroprotective therapies in prodromal Huntington's disease.

Published in:

Movement Disorders, 2014, v. 29, n. 3, p. 285, doi. 10.1002/mds.25835

By:

Chandra, Abhishek;
Johri, Ashu;
Beal, M. Flint

Publication type:

Article

Mitochondrial therapies for Parkinson's disease.

Published in:

Movement Disorders, 2010, v. 25, n. S1, p. S155, doi. 10.1002/mds.22781

By:

Thomas, Bobby;
Beal, M. Flint

Publication type:

Article

Limited-time exposure to mitochondrial toxins may lead to chronic progressive neurodegenerative diseases.

Published in:

2000

By:

Beal, M. Flint;
Beal, M F

Publication type:

Editorial

Riluzole therapy in Huntington's disease (HD).

Published in:

Movement Disorders, 1999, v. 14, n. 2, p. 326, doi. 10.1002/1531-8257(199903)14:2<326::AID-MDS1019>3.0.CO;2-Q

By:

Rosas, H. Diana;
Koroshetz, Walter J.;
Jenkins, Bruce G.;
Chen, Y. Iris;
Hayden, Douglas L.;
Beal, M. Flint;
Cudkowicz, Merit E.

Publication type:

Article

Isotope-reinforced polyunsaturated fatty acids improve Parkinson's disease-like phenotype in rats overexpressing α-synuclein.

Published in:

Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40478-020-01090-6

By:

Beal, M. Flint;
Chiluwal, Jayandra;
Calingasan, Noel Y.;
Milne, Ginger L.;
Shchepinov, Mikhail S.;
Tapias, Victor

Publication type:

Article

Modulation of mitochondrial and inflammatory homeostasis through RIP140 is neuroprotective in an adrenoleukodystrophy mouse model.

Published in:

Neuropathology & Applied Neurobiology, 2022, v. 48, n. 1, p. 1, doi. 10.1111/nan.12747

By:

Ranea‐Robles, Pablo;
Galino, Jorge;
Espinosa, Lluís;
Schlüter, Agatha;
Ruiz, Montserrat;
Calingasan, Noel Ylagan;
Villarroya, Francesc;
Naudí, Alba;
Pamplona, Reinald;
Ferrer, Isidre;
Beal, M. Flint;
Portero‐Otín, Manuel;
Fourcade, Stéphane;
Pujol, Aurora

Publication type:

Article

Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer's disease.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-021-27572-2

By:

Yang, Yun;
Tapias, Victor;
Acosta, Diana;
Xu, Hui;
Chen, Huanlian;
Bhawal, Ruchika;
Anderson, Elizabeth T.;
Ivanova, Elena;
Lin, Hening;
Sagdullaev, Botir T.;
Chen, Jianer;
Klein, William L.;
Viola, Kirsten L.;
Gandy, Sam;
Haroutunian, Vahram;
Beal, M. Flint;
Eliezer, David;
Zhang, Sheng;
Gibson, Gary E.

Publication type:

Article

Concordant Signaling Pathways Produced by Pesticide Exposure in Mice Correspond to Pathways Identified in Human Parkinson's Disease.

Published in:

PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0036191

By:

Gollamudi, Seema;
Johri, Ashu;
Calingasan, Noel Y.;
Lichuan Yang;
Elemento, Olivier;
Beal, M. Flint

Publication type:

Article

Dopaminergic Neuronal Loss, Reduced Neurite Complexity and Autophagic Abnormalities in Transgenic Mice Expressing G2019S Mutant LRRK2.

Published in:

PLoS ONE, 2011, v. 6, n. 4, p. 1, doi. 10.1371/journal.pone.0018568

By:

Ramonet, David;
Daher, João Paulo L.;
Lin, Brian M.;
Stafa, Klodjan;
Jaekwang Kim;
Banerjee, Rebecca;
Westerlund, Marie;
Pletnikova, Olga;
Glauser, Liliane;
Lichuan Yang;
Ying Liu;
Swing, Deborah A.;
Beal, M. Flint;
Troncoso, Juan C.;
McCaffery, J. Michael;
Jenkins, Nancy A.;
Copeland, Neal G.;
Galter, Dagmar;
Thomas, Bobby;
Lee, Michael K.

Publication type:

Article

MicroRNA-Related Cofilin Abnormality in Alzheimer's Disease.

Published in:

PLoS ONE, 2010, v. 5, n. 12, p. 1, doi. 10.1371/journal.pone.0015546

By:

Yao, Jiaqi;
Hennessey, Tom;
Flynt, Alex;
Lai, Eric;
Beal, M. Flint;
Lin, Michael T.

Publication type:

Article

Metabolomic Profiling in LRRK2-Related Parkinson's Disease.

Published in:

PLoS ONE, 2009, v. 4, n. 10, p. 1, doi. 10.1371/journal.pone.0007551

By:

Johansen, Krisztina K.;
Lei Wang;
Aasly, Jan O.;
White, Linda R.;
Matson, Wayne R.;
Henchcliffe, Claire;
Beal, M. Flint;
Bogdanov, Mikhail

Publication type:

Article

Neuroprotective Effects of the Triterpenoid, CDDO Methyl Amide, a Potent Inducer of Nrf2-Mediated Transcription.

Published in:

PLoS ONE, 2009, v. 4, n. 6, p. 1, doi. 10.1371/journal.pone.0005757

By:

Lichuan Yang;
Calingasan, Noel Y.;
Thomas, Bobby;
Chaturvedi, Rajnish K.;
Kiaei, Mahmoud;
Wille, Elizabeth J.;
Liby, Karen T.;
Williams, Charlotte;
Royce, Darlene;
Risingsong, Renee;
Musiek, Eric S.;
Morrow, Jason D.;
Sporn, Michael;
Beal, M. Flint

Publication type:

Article

PINK1 Defect Causes Mitochondrial Dysfunction, Proteasomal Deficit and α-Synuclein Aggregation in Cell Culture Models of Parkinson's Disease.

Published in:

PLoS ONE, 2009, v. 4, n. 2, p. 1, doi. 10.1371/journal.pone.0004597

By:

Wencheng Liu;
Vives-Bauza, Cristofol;
Acín-Peréz, Rebeca;
Yamamoto, Ai;
Yingcai Tan;
Yanping Li;
Magrané, Jordi;
Stavarache, Mihaela A.;
Shaffer, Sebastian;
Chang, Simon;
Kaplitt, Michael G.;
Huang, Xin-Yun;
Beal, M. Flint;
Manfredi, Giovanni;
Chenjian Li

Publication type:

Article

Beneficial effects of creatine, CoQ<sub>10</sub>, and lipoic acid in mitochondrial disorders.

Published in:

Muscle & Nerve, 2007, v. 35, n. 2, p. 235, doi. 10.1002/mus.20688

By:

Rodriguez, M. Christine;
MacDonald, Jay R.;
Mahoney, Douglas J.;
Parise, Gianni;
Beal, M. Flint;
Tarnopolsky, Mark A.

Publication type:

Article

Thalidomide and Lenalidomide Extend Survival in a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis.

Published in:

Journal of Neuroscience, 2006, v. 26, n. 9, p. 2467, doi. 10.1523/JNEUROSCI.5253-05.2006

By:

Kiaei, Mahmoud;
Petri, Susanne;
Kipiani, Khatuna;
Gardian, Gabrielle;
Dong-Kug Choi;
Junyu Chen;
Calingasan, Noel Y.;
Schafer, Peter;
Muller, George W.;
Stewart, Charles;
Hensley, Kenneth;
Beal, M. Flint

Publication type:

Article

Matrix Metalloproteinase-3: A Novel Signaling Proteinase from Apoptotic Neuronal Cells That Activates Microglia.

Published in:

Journal of Neuroscience, 2005, v. 25, n. 14, p. 3701, doi. 10.1523/JNEUROSCI.4346-04.2005

By:

Yoon Seong Kim;
Sung Soo Kim;
Jeong Je Cho;
Dong Hoon Shin;
Dong Hee Choi;
Onyou Hwang;
Hong Sung Chun;
Beal, M. Flint;
Joh, Tong H.

Publication type:

Article

Mutant Superoxide Dismutase 1 Forms Aggregates in the Brain Mitochondrial Matrix of Amyotrophic Lateral Sclerosis Mice.

Published in:

Journal of Neuroscience, 2005, v. 25, n. 10, p. 2463, doi. 10.1523/JNEUROSCI.4385-04.2005

By:

Vijayvergiya, Chetan;
Beal, M. Flint;
Buck, Jochen;
Manfredi, Giovanni

Publication type:

Article

Chemotherapy for the Brain: The Antitumor Antibiotic Mithramycin Prolongs Survival in a Mouse Model of Huntington's Disease.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 46, p. 10335, doi. 10.1523/JNEUROSCI.2599-04.2004

By:

Ferrante, Robert J.;
Ryu, Hoon;
Kubilus, James K.;
Lee, Junghee;
Smith, Karen;
D'Mello, Santosh;
Sugars, Katharine L.;
Rubinsztein, David C.;
Lu, Peiyuan;
Langley, Brett;
Browne, Susan;
Beal, M. Flint;
Hewett, Sandra;
Kristal, Bruce S.;
Stavrovskaya, Irina G.;
Ratan, Rajiv R.

Publication type:

Article

Genetically Decreased Spinal Cord Copper Concentration Prolongs Life in a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 36, p. 7945, doi. 10.1523/JNEUROSCI.2000-04.2004

By:

Kiaei, Mahmoud;
Bush, Ashley I.;
Morrison, Brett M.;
Morrison, John H.;
Cherny, Robert A.;
Volitakis, Irene;
Beal, M. Flint;
Gordon, Jon W.

Publication type:

Article

Mitochondrial α-Ketoglutarate Dehydrogenase Complex Generates Reactive Oxygen Species.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 36, p. 7779, doi. 10.1523/JNEUROSCI.1899-04.2004

By:

Starkov, Anatoly A.;
Fiskum, Gary;
Chinopoulos, Christos;
Lorenzo, Beverly J.;
Browne, Susan E.;
Patel, Mulchand S.;
Beal, M. Flint

Publication type:

Article

Prophylactic Creatine Administration Mediates Neuroprotection in Cerebral Ischemia in Mice.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 26, p. 5909, doi. 10.1523/JNEUROSCI.1278-04.2004

By:

Shan Zhu;
Mingwei Li;
Figueroa, Bryan E.;
Aijian Liu;
Stavrovskaya, Irina G.;
Pasinelli, Piera;
Beal, M. Flint;
Brown Jr., Robert H.;
Kristal, Bruce S.;
Ferrante, Robert J.;
Friedlander, Robert M.

Publication type:

Article

Galanin immunoreactivity is increased in the nucleus basalis of meynert in Alzheimer's disease.

Published in:

Annals of Neurology, 1990, v. 28, n. 2, p. 157, doi. 10.1002/ana.410280207

By:

Beal, M. Flint;
MacGarvey, Usha;
Swartz, Kenton J.

Publication type:

Article

Selective sparing of NADPH-diaphorase-somatostatin-neuropeptide Y neurons in ischemic gerbil striatum.

Published in:

Annals of Neurology, 1990, v. 27, n. 6, p. 620, doi. 10.1002/ana.410270606

By:

Uemura, Yoshihiko;
Kowall, Neil W.;
Beal, M. Flint

Publication type:

Article

Cerebrospinal fluid neurochemistry in the myoclonic subtype of Alzheimer's disease.

Published in:

Annals of Neurology, 1988, v. 24, n. 5, p. 647, doi. 10.1002/ana.410240509

By:

Kaye, Jeffrey A.;
May, Conrad;
Atack, John R.;
Daly, Eileen;
Sweeney, Daniel L.;
Flint Beal, M.;
Kaufman, Seymour;
Milstien, Sheldon;
Friedland, Robert P.;
Rapoport, Stanley I.

Publication type:

Article

Somatostatin and neuropeptide Y concentrations in pathologically graded cases of huntington's disease.

Published in:

Annals of Neurology, 1988, v. 23, n. 6, p. 562, doi. 10.1002/ana.410230606

By:

Beal, M. Flint;
Mazurek, Michael F.;
Ellison, David W.;
Swartz, Kenton J.;
McGarvey, Usha;
Bird, Edward D.;
Martin, Joseph B.

Publication type:

Article

Cortical somatostatin, neuropeptide Y, and NADPH diaphorase neurons: Normal anatomy and alterations in alzheimer's disease.

Published in:

Annals of Neurology, 1988, v. 23, n. 2, p. 105, doi. 10.1002/ana.410230202

By:

Kowall, Neil W.;
Beal, M. Flint

Publication type:

Article

Neuropeptides in neurological disease.

Published in:

Annals of Neurology, 1986, v. 20, n. 5, p. 547, doi. 10.1002/ana.410200502

By:

Beal, M. Flint;
Martin, Joseph B.

Publication type:

Article

A postmortem study of amino acid neurotransmitters in Alzheimer's disease.

Published in:

Annals of Neurology, 1986, v. 20, n. 5, p. 616, doi. 10.1002/ana.410200510

By:

Ellison, David W.;
Beal, M. Flint;
Mazurek, Michael F.;
Bird, Edward D.;
Martin, Joseph B.

Publication type:

Article

Neuropeptide Y immunoreactivity is reduced in cerebral cortex in Alzheimer's disease.

Published in:

Annals of Neurology, 1986, v. 20, n. 3, p. 282, doi. 10.1002/ana.410200303

By:

Beal, M. Flint;
Mazurek, Michael F.;
Chattha, Geetinder K.;
Svendsen, Clive N.;
Bird, Edward D.;
Martin, Joseph B.

Publication type:

Article

Widespread reduction of somatostatin-like immunoreactivity in the cerebral cortex in Alzheimer's disease.

Published in:

Annals of Neurology, 1986, v. 20, n. 4, p. 489, doi. 10.1002/ana.410200408

By:

Beal, M. Flint;
Mazurek, Michael F.;
Svendsen, Clive N.;
Bird, Edward D.;
Martin, Joseph B.

Publication type:

Article

The negative impact of α-ketoglutarate dehydrogenase complex deficiency on matrix substrate-level phosphorylation.

Published in:

FASEB Journal, 2013, v. 27, n. 6, p. 2392, doi. 10.1096/fj.12-220202

By:

Kiss, Gergely;
Konrad, Csaba;
Doczi, Judit;
Starkov, Anatoly A.;
Kawamata, Hibiki;
Manfredi, Giovanni;
Zhang, Steven F.;
Gibson, Gary E.;
Beal, M. Flint;
Adam-Vizi, Vera;
Chinopoulos, Christos

Publication type:

Article