Works matching DE "DIHYDROPYRIMIDINE dehydrogenase"
Results: 313
Indirect assessment of dihydropyrimidine dehydrogenase activity in cats.
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- Veterinary & Comparative Oncology, 2013, v. 11, n. 4, p. 265, doi. 10.1111/vco.12064
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- Article
Peptide nucleic acid Hoogsteen strand linker design for major groove recognition of DNA thymine bases.
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- Journal of Computer-Aided Molecular Design, 2021, v. 35, n. 3, p. 355, doi. 10.1007/s10822-021-00375-9
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- Article
Identification of fungal dihydrouracil-oxidase genes by expression in Saccharomyces cerevisiae.
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- Antonie van Leeuwenhoek, 2022, v. 115, n. 11, p. 1363, doi. 10.1007/s10482-022-01779-9
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- Article
Reaction of 2-(2-oxo-2-arylethylidene)-2,3-dihydropyrimidine-4(1 H)-ones with aldehydes.
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- Russian Journal of General Chemistry, 2014, v. 84, n. 5, p. 869, doi. 10.1134/S1070363214050156
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- Article
Enhanced efficacy of 5-fluorouracil combined with chrysin in treating colorectal cancer in BALB/c mice: Impact on β-catenin and inducible nitric oxide synthase expression.
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- Indian Journal of Natural Products & Resources, 2023, v. 14, n. 2, p. 229, doi. 10.56042/ijnpr.v14i2.4207
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- Article
The Allosteric Regulation of Β-Ureidopropionase Depends on Fine-Tuned Stability of Active-Site Loops and Subunit Interfaces.
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- Biomolecules (2218-273X), 2023, v. 13, n. 12, p. 1763, doi. 10.3390/biom13121763
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- Article
Complexed Crystal Structure of the Dihydroorotase Domain of Human CAD Protein with the Anticancer Drug 5-Fluorouracil.
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- Biomolecules (2218-273X), 2023, v. 13, n. 1, p. 149, doi. 10.3390/biom13010149
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- Article
Development of Artificial System to Induce Chromatin Loosening in Saccharomyces cerevisiae.
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- Biomolecules (2218-273X), 2022, v. 12, n. 8, p. 1138, doi. 10.3390/biom12081138
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- Article
Case report: 5-Fluorouracil treatment in patient with an important partial DPD deficiency.
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- Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1187052
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- Article
Biochemical, Clinical, and Genetic Characteristics of Short/Branched Chain Acyl-CoA Dehydrogenase Deficiency in Chinese Patients by Newborn Screening.
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- Frontiers in Genetics, 2019, p. 1, doi. 10.3389/fgene.2019.00802
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- Article
A PRACTICAL GREEN SYNTHESIS OF THIAZINE DERIVATIVES USING PHASE TRANSFER CATALYST.
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- Rasayan Journal of Chemistry, 2018, v. 11, n. 3, p. 1294, doi. 10.31788/RJC.2018.1134012
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- Article
Diagnostic and Therapeutic Strategies for Fluoropyrimidine Treatment of Patients Carrying Multiple DPYD Variants.
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- Genes, 2018, v. 9, n. 12, p. 585, doi. 10.3390/genes9120585
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- Article
Synthesis, Spectral Characterization and Analgesic Activity of 2-Methylthio-1,4-Dihydropyrimidines.
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- Iranian Journal of Pharmaceutical Research, 2011, v. 10, n. 4, p. 733
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- Article
A General, Effcient and Green Procedure for Synthesis of Dihydropyrimidine-5-carboxamides in Low Melting Betaine Hydrochloride/Urea Mixture.
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- Chinese Journal of Chemistry, 2016, v. 34, n. 6, p. 637, doi. 10.1002/cjoc.201500862
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- Article
MIR27A Gene Polymorphism Modifies the Effect of Common DPYD Gene Variants on Severe Toxicity in Patients with Gastrointestinal Tumors Treated with Fluoropyrimidine-Based Anticancer Therapy.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 15, p. 8503, doi. 10.3390/ijms25158503
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- Article
Approach for Phased Sequence-Based Genotyping of the Critical Pharmacogene Dihydropyrimidine Dehydrogenase (DPYD).
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- International Journal of Molecular Sciences, 2024, v. 25, n. 14, p. 7599, doi. 10.3390/ijms25147599
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- Article
The Importance of Anharmonicity and Solvent Effects on the OH Radical Attack on Nucleobases.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 6, p. 3118, doi. 10.3390/ijms25063118
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- Article
Development of Novel Class of Phenylpyrazolo[3,4- d ]pyrimidine-Based Analogs with Potent Anticancer Activity and Multitarget Enzyme Inhibition Supported by Docking Studies.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 19, p. 15026, doi. 10.3390/ijms241915026
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- Article
Genetic Variation in miR-27a Is Associated with Fluoropyrimidine-Associated Toxicity in Patients with Dihydropyrimidine Dehydrogenase Variants after Genotype-Guided Dose Reduction.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 17, p. 13284, doi. 10.3390/ijms241713284
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- Article
Prognostic Impact of Dihydropyrimidine Dehydrogenase Germline Variants in Unresectable Non-Small Cell Lung Cancer Patients Treated with Platin-Based Chemotherapy.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 12, p. 9843, doi. 10.3390/ijms24129843
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- Article
Predicting Dihydropyrimidine Dehydrogenase Deficiency and Related 5-Fluorouracil Toxicity: Opportunities and Challenges of DPYD Exon Sequencing and the Role of Phenotyping Assays.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 22, p. 13923, doi. 10.3390/ijms232213923
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- Article
Systematical Screening of Intracellular Protein Targets of Polyphemusin-I Using Escherichia coli Proteome Microarrays.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 17, p. 9158, doi. 10.3390/ijms22179158
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- Article
Detection of Genomic Uracil Patterns.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 8, p. 3902, doi. 10.3390/ijms22083902
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- Article
Undetected Toxicity Risk in Pharmacogenetic Testing for Dihydropyrimidine Dehydrogenase.
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- International Journal of Molecular Sciences, 2015, v. 16, n. 4, p. 8884, doi. 10.3390/ijms16048884
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- Article
The Stereoselectivity and Hydrolysis Efficiency of Recombinant d-Hydantoinase from Vigna angularis Against 5-Benzylhydantoin Derivatives with Halogen and Methyl Substituents.
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- Applied Biochemistry & Biotechnology, 2015, v. 175, n. 2, p. 698, doi. 10.1007/s12010-014-1313-4
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- Article
Effects of demethylating reagent 5-aza-2′-deoxycytidine on the growth and cephalotaxine production in Cephalotaxus mannii suspension cells.
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- Plant Cell, Tissue & Organ Culture, 2019, v. 139, n. 2, p. 359, doi. 10.1007/s11240-019-01689-1
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- Article
Role of thymidylate synthase and dihydropyrimidine dehydrogenase mRNA expressions in gallbladder carcinoma.
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- Surgery Today, 2012, v. 42, n. 6, p. 565, doi. 10.1007/s00595-012-0118-8
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- Article
A rapid, safe, and quantitative in vitro assay for measurement of uracil-DNA glycosylase activity.
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- Journal of Molecular Medicine, 2019, v. 97, n. 7, p. 991, doi. 10.1007/s00109-019-01788-8
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- Article
Evaluation of the Hepatoprotective Effect of L-Ascorbate 1-(2-Hydroxyethyl)-4,6-Dimethyl-1,2-Dihydropyrimidine-2-One Upon Exposure to Carbon Tetrachloride.
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- Bulletin of Experimental Biology & Medicine, 2017, v. 162, n. 3, p. 340, doi. 10.1007/s10517-017-3610-8
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- Article
The relative rate of kill of the MMV Malaria Box compounds provides links to the mode of antimalarial action and highlights scaffolds of medicinal chemistry interest.
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- 2020
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- journal article
Substrate Diversity of L-Threonic Acid Dehydrogenase Homologs.
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- Biochemistry (00062979), 2020, v. 85, n. 4, p. 463, doi. 10.1134/S0006297920040069
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- Article
Eritrodisestesia palmoplantar tras tratamiento perioperatorio con quimioterapia.
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- Sanidad Militar, 2022, v. 78, n. 4, p. 258, doi. 10.4321/S1887-85712022000400009
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- Article
Potassium Fluoride-Modified Clay as a Reusable Heterogeneous Catalyst for One-Pot Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones.
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- Russian Journal of Organic Chemistry, 2019, v. 55, n. 9, p. 1423, doi. 10.1134/S1070428019090240
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- Article
Synthesis of ( S)-(-)-1,4-diaryl-6-methyl-4-trifluoromethyl-3,4-dihydropyrimidine-2(1 H)-thiones.
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- Russian Journal of Organic Chemistry, 2012, v. 48, n. 3, p. 430, doi. 10.1134/S1070428012030165
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- Article
Intratumoural expression of dihydropyrimidine dehydrogenase is an independent prognostic factor in resected pancreatic ductal adenocarcinoma treated with adjuvant gemcitabine.
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- Oncology Letters, 2025, v. 29, n. 2, p. N.PAG, doi. 10.3892/ol.2024.14845
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- Article
Potential Impact of DPYD Variation on Fluoropyrimidine Drug Response in sub-Saharan African Populations.
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- Frontiers in Genetics, 2021, v. 11, p. N.PAG, doi. 10.3389/fgene.2021.626954
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- Article
Food‐effect study on uracil and dihydrouracil plasma levels as marker for dihydropyrimidine dehydrogenase activity in human volunteers.
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- British Journal of Clinical Pharmacology, 2018, v. 84, n. 12, p. 2761, doi. 10.1111/bcp.13719
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- Article
Pronounced between-subject and circadian variability in thymidylate synthase and dihydropyrimidine dehydrogenase enzyme activity in human volunteers.
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- British Journal of Clinical Pharmacology, 2016, v. 82, n. 3, p. 706, doi. 10.1111/bcp.13007
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- Article
Evaluation of an oral uracil loading test to identify DPD-deficient patients using a limited sampling strategy.
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- British Journal of Clinical Pharmacology, 2016, v. 81, n. 3, p. 553, doi. 10.1111/bcp.12821
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- Article
Beating the odds: efficacy and toxicity of dihydropyrimidine dehydrogenase-driven adaptive dosing of 5-FU in patients with digestive cancer.
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- British Journal of Clinical Pharmacology, 2016, v. 81, n. 1, p. 124, doi. 10.1111/bcp.12790
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- Article
Histone mRNA is subject to 3′ uridylation and re‐adenylation in Aspergillus nidulans.
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- Molecular Microbiology, 2021, v. 115, n. 2, p. 238, doi. 10.1111/mmi.14613
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- Article
5-Fluorouracil Rechallenge After Cardiotoxicity.
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- American Journal of Case Reports, 2020, v. 21, p. 1, doi. 10.12659/AJCR.924446
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- Article
Value of plasma SN-38 levels and DPD activity in irinotecan-based individualized chemotherapy for advanced colorectal cancer with heterozygous type UGT1A1*6 or UGT1A1*28.
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- Cancer Management & Research, 2018, v. 10, p. 6217, doi. 10.2147/CMAR.S176918
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- Article
Severe toxicity to capecitabine due to a new variant at a donor splicing site in the dihydropyrimidine dehydrogenase <em>(DPYD)</em> gene.
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- Cancer Management & Research, 2018, v. 10, p. 4517, doi. 10.2147/CMAR.S174470
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- Article
Discovering novel germline genetic variants linked to severe fluoropyrimidine-related toxicity in- and outside DPYD.
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- Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01354-z
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- Article
Expression level of dihydropyrimidine dehydrogenase is associated with clinical outcome in patients with T1G3 bladder cancer treated with Bacillus Calmette-Guerin.
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- BMC Research Notes, 2014, p. 1, doi. 10.1186/1756-0500-7-646
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- Article
Leukoencephalopathy with transient splenial lesions related to 5‐fluorouracil or capecitabine.
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- European Journal of Neurology, 2021, v. 28, n. 7, p. 2396, doi. 10.1111/ene.14857
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- Article
EFFECTS OF CERTAIN DRUGS ON DIHYDROPYRIMIDINE DEHYDROGENASE ENZYME PURIFIED FROM BOVINE LIVER.
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- Slovenian Veterinary Research / Slovenski Veterinarski Zbornik, 2017, v. 54, n. 2, p. 59
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- Article
Pseudomonas putida PydR, a RutR-like transcriptional regulator, represses the dihydropyrimidine dehydrogenase gene in the pyrimidine reductive catabolic pathway.
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- Journal of Biochemistry, 2012, v. 152, n. 4, p. 341, doi. 10.1093/jb/mvs079
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- Article
Crystal structure of 6-oxo-4-propyl-2-(propylthio)-1,6-dihydropyrimidine-5-carbonitrile, C<sub>11</sub>H<sub>15</sub>N<sub>3</sub>OS.
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- Zeitschrift für Kristallographie / New Crystal Structures, 2016, v. 231, n. 2, p. 583, doi. 10.1515/ncrs-2015-0198
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- Article