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Title

Association Between Waist Circumference and Dementia in Older Persons: A Nationwide Population-Based Study.

Authors

Cho, Geum Joon; Hwang, Soon Young; Lee, Kyu‐Min; Choi, Kyung Mook; Hyun Baik, Sei; Kim, Tak; Han, Sung Won; Yoo, Hye Jin; Lee, Kyu-Min

Abstract

<bold>Objective: </bold>This study examined whether a positive association exists between waist circumference (WC) and dementia among older persons.<bold>Methods: </bold>The study population comprised 872,082 participants aged 65 years and older who participated in a Korean national health screening examination between January 1, 2009, and December 31, 2009. Adjusted hazard ratios and 95% CIs for dementia during follow-up from 2009 to 2015 were calculated according to baseline BMI and WC categories.<bold>Results: </bold>After a multivariate adjustment that included BMI, the hazard ratios for dementia showed a stepwise increase according to the increase in WC categories by 5 cm from 85 to 90 cm in men and from 80 to 85 cm in women until ≥ 110 cm (from 1.06 [95% CI: 1.03-1.09] to 1.64 [95% CI: 1.37-1.94] in men and from 1.04 [95% CI: 1.02-1.07] to 1.58 [95% CI: 1.36-1.84] in women). The influence of the current WC category for abdominal obesity on the risk of dementia was different according to BMI; especially, the normal weight men and women with abdominal obesity had a prominent increased risk of dementia compared with those without abdominal obesity.<bold>Conclusions: </bold>Abdominal obesity, as measured by WC, was associated with significantly increased risk of dementia after adjustment for general obesity.

Subjects

SOUTH Korea; OLDER people; WAIST circumference; DEMENTIA; OBESITY in women; PERIODIC health examinations; OBESITY complications; OBESITY & psychology; OBESITY; DATABASES; RESEARCH; AGE distribution; RESEARCH methodology; EVALUATION research; MEDICAL cooperation; COMPARATIVE studies; HEALTH of older people; RESEARCH funding; BODY mass index; LONGITUDINAL method; DISEASE complications

Publication

Obesity (19307381), 2019, Vol 27, Issue 11, p1883

ISSN

1930-7381

Publication type

Academic Journal

DOI

10.1002/oby.22609

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