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- Title
Relaxation spectral analysis in multi-contrast vascular magnetic particle imaging.
- Authors
Feng, Xin; Jia, Guang; Peng, Jiaming; Huang, Liyu; Liang, Xiaofeng; Zhang, Haoran; Liu, Yanjun; Zhang, Bo; Zhang, Yifei; Sun, Meng; Li, Peng; Miao, Qiguang; Wang, Ying; Xi, Li; Hu, Kai; Li, Tanping; Hui, Hui; Tian, Jie
- Abstract
Magnetic nanoparticles (MNPs) are used as tracers without ionizing radiation in vascular imaging, molecular imaging, and neuroimaging. The relaxation mechanisms of magnetization in response to excitation magnetic fields are important features of MNPs. The basic relaxation mechanisms include internal rotation (Néel relaxation) and external physical rotation (Brownian relaxation). Accurate measurement of these relaxation times may provide high sensitivity for predicting MNP types and viscosity-based hydrodynamic states. It is challenging to separately measure the Néel and Brownian relaxation components using sinusoidal excitation in conventional MPI.
- Publication
Medical physics, 2023, Vol 50, Issue 7, p4651
- ISSN
2473-4209
- Publication type
Journal Article
- DOI
10.1002/mp.16551