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- Title
Development and CT image-domain validation of a computational lung lesion model for use in virtual imaging trials.
- Authors
Sauer, Thomas J; Bejan, Adrian; Segars, Paul; Samei, Ehsan
- Abstract
Computational abnormalities (e.g., lesion models) for use in medical imaging simulation studies are frequently generated using data collected from clinical images. Although this approach allows for highly-customizable lesion detectability studies on clinical computed tomography (CT) data, the ground-truth lesion models produced with this method do not provide a sufficiently realistic lesion morphology for use with current anthropomorphic simulation studies. This work is intended to demonstrate that the new anatomically-informed lesion model presented here is not inferior to the previous lesion model under CT imaging, and can therefore provide a more biologically-informed model for use with simulated CT imaging studies.
- Publication
Medical physics, 2023, Vol 50, Issue 7, p4366
- ISSN
2473-4209
- Publication type
Journal Article
- DOI
10.1002/mp.16222