Synthesis and UV Cross‐Linking of Methacrylated Linear and Star‐Shaped Lactide Oligomers as Potential Biodegradable Resins for Stereolithography.

Sedush, Nikita; Kalinin, Kirill; Puchkov, Alexander; Chvalun, Sergei

Stereolithography and DLP printing attract a lot of attention in medical field as techniques for fabrication of personalized implants and various medical devices. However, there is a lack of photo‐curable resins for fabrication of biodegradable tissue engineering constructs and implants. In this work biodegradable UV‐curable d,l‐lactide oligomers are presented, which can be good candidates as resins for SLA and DLP 3D printing. Linear and star‐shaped (3‐ and 6‐arm) methacrylated d,l‐lactide oligomers with different molecular weight are synthesized and cross‐linked in various conditions. UV‐curing is performed at elevated temperatures in the absence of any diluents and revealed formation of gel fraction, which has achieved 99%. The cross‐linked materials demonstrate high tensile modulus (up to 1.8 GPa), suggesting the resins are perspective for fabrication of load‐bearing implants.

STEREOLITHOGRAPHY; OLIGOMERS; THREE-dimensional printing; HIGH temperatures; MOLECULAR weights; BIODEGRADABLE materials; HYDROXYAPATITE coating

Macromolecular Symposia, 2022, Vol 404, Issue 1, p1

1022-1360

Academic Journal

10.1002/masy.202100380