Highlights from the article: The 12 SP th sp International IUPAC Conference on Polymer-Solvent Complexes and Intercalates (POLYSOLVAT-12) took place at Institut Laue-Langevin (ILL) in Grenoble (France) on September 4-7, 2018. It was jointly organized by Centre de Recherches sur les Macromolécules Végétales (CERMAV) and ILL, and sponsored by Institut Carnot PolyNat, Institut de Chimie Moléculaire de Grenoble (ICMG), Université Grenoble Alpes (UGA), Grenoble INP, the Glyco@Alps Cross Disciplinary Program, CNRS and IUPAC. Institut Laue-Langevin (ILL).