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- Title
Hepatoprotective effects and mechanisms of l-theanine and epigallocatechin gallate combined intervention in alcoholic fatty liver rats.
- Authors
Xu, Kai-Hang; Yang, Di-Fei; Liu, Meng-Yuan; Xu, Wei; Li, Yin-Hua; Xiao, Wen-Jun
- Abstract
Chronic excessive alcohol consumption can lead to alcoholic fatty liver, posing substantial health risks. l-Theanine (LTA) and epigallocatechin gallate (EGCG) in tea exert antioxidant and hepatoprotective effects. However, the combined effects of LTA and EGCG on rats with alcoholic fatty liver, and the underlying mechanisms of such effects, remain unclear. In this study, Sprague Dawley (SD) rats were fed with alcohol for 6 weeks to induce alcoholic fatty liver. Subsequently, for another 6 weeks, the rats were administered LTA (200 mg kg -1 day -1 ), EGCG (200 mg kg -1 day -1 ), or a combination of LTA with EGCG (40 mg kg -1 day -1 l-Thea 160 mg kg -1 day -1 EGCG), respectively.
- Publication
Journal of the science of food and agriculture, 2024, Vol 104, Issue 13, p8230
- ISSN
1097-0010
- Publication type
Journal Article
- DOI
10.1002/jsfa.13658