The article focuses on the study aims to describe the drought forecasting with the use of Artificial Neural Network (ANN) and to predict quantitative values of drought indices which measure the degree of dryness of any time period in Iran. The indices serve as Effective Drought Index (EDI) and the Standard Precipitation Index (SPI). Moreover, there are two predicants most commonly used in medium-range climate forecasting such as El Nino Southern Oscillation (ENSO) and North Atlantic Oscillation (NAO) indices. Thus, the study found that the final forecasting models can be utilized by drought early warning systems.