Works matching AU De Clercq, Erik
Results: 301
Synthesis of 5′- N-(α-Amino-β-mercaptoacyl)amino-5′-deoxynucleosides as potential antiviral compounds.
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- Archiv der Pharmazie, 1991, v. 324, n. 8, p. 497, doi. 10.1002/ardp.2503240807
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Synthese und antivirale Aktivität von 2,3(1H, 4H)-Chinoxalindion-Derivaten.
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- Archiv der Pharmazie, 1987, v. 320, n. 3, p. 271, doi. 10.1002/ardp.19873200315
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Synthesis and Antiviral Activity of Acyclic Derivatives of 5-Ethyl-2′-Deoxyuridine.
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- Archiv der Pharmazie, 1986, v. 319, n. 4, p. 360, doi. 10.1002/ardp.19863190412
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Prodrugs of 5-Ethyl-2′-deoxyuridine, II Syntheses and Antiviral Activities of 5′- and 3′-Ester Derivatives.
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- Archiv der Pharmazie, 1986, v. 319, n. 2, p. 154, doi. 10.1002/ardp.19863190212
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Syntheses and Antiviral Activities of Some 5′- O-Acyl Derivatives.
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- Archiv der Pharmazie, 1984, v. 317, n. 10, p. 867, doi. 10.1002/ardp.19843171011
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Assessment of the in vitro broad-spectrum antiviral activity of some selected antitumor metallocene and metallocenium complexes.
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- Applied Organometallic Chemistry, 1989, v. 3, n. 6, p. 491, doi. 10.1002/aoc.590030605
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Assessment of the in vitro broad-spectrum antiviral activity of some selected antitumor organotin complexes.
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- Applied Organometallic Chemistry, 1989, v. 3, n. 5, p. 431, doi. 10.1002/aoc.590030509
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The Acyclic Nucleoside Phosphonates (ANPs): Antonín Holý's Legacy.
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- Medicinal Research Reviews, 2013, v. 33, n. 6, p. 1278, doi. 10.1002/med.21283
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A Cutting-Edge View on the Current State of Antiviral Drug Development.
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- Medicinal Research Reviews, 2013, v. 33, n. 6, p. 1249, doi. 10.1002/med.21281
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Highlights in Antiviral Drug Research: Antivirals at the Horizon.
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- Medicinal Research Reviews, 2013, v. 33, n. 6, p. 1215, doi. 10.1002/med.21256
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Organic Chemist Whose Inventions Reshaped the Antiviral Drug World.
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- Medicinal Research Reviews, 2013, v. 33, n. 1, p. 1, doi. 10.1002/med.21274
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Tenofovir: Quo Vadis Anno 2012 (Where Is It Going in the Year 2012)?
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- Medicinal Research Reviews, 2012, v. 32, n. 4, p. 765, doi. 10.1002/med.21267
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The next ten stories on antiviral drug discovery (part E): advents, advances, and adventures.
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- Medicinal Research Reviews, 2011, v. 31, n. 1, p. 118, doi. 10.1002/med.20179
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Yet another ten stories on antiviral drug discovery (part D): Paradigms, paradoxes, and paraductions.
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- Medicinal Research Reviews, 2010, v. 30, n. 4, p. 667, doi. 10.1002/med.20173
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Another ten stories in antiviral drug discovery (part C): 'Old' and 'new' antivirals, strategies, and perspectives.
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- Medicinal Research Reviews, 2009, v. 29, n. 4, p. 611, doi. 10.1002/med.20153
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Antiviral drug discovery: Ten more compounds, and ten more stories (part B).
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- Medicinal Research Reviews, 2009, v. 29, n. 4, p. 571, doi. 10.1002/med.20149
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Selective inhibitors of picornavirus replication.
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- Medicinal Research Reviews, 2008, v. 28, n. 6, p. 823, doi. 10.1002/med.20125
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The discovery of antiviral agents: Ten different compounds, ten different stories.
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- Medicinal Research Reviews, 2008, v. 28, n. 6, p. 929, doi. 10.1002/med.20128
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Anti-influenza virus agents: Synthesis and mode of action.
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- Medicinal Research Reviews, 2008, v. 28, n. 1, p. 1, doi. 10.1002/med.20096
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The regulation of HIV-1 transcription: Molecular targets for chemotherapeutic intervention.
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- Medicinal Research Reviews, 2006, v. 26, n. 5, p. 595, doi. 10.1002/med.20081
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( E)-5-(2-bromovinyl)-2′-deoxyuridine (BVDU).
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- Medicinal Research Reviews, 2005, v. 25, n. 1, p. 1, doi. 10.1002/med.20011
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Highly potent and selective inhibition of varicella-zoster virus replication by bicyclic furo[2,3-d]pyrimidine nucleoside analogues (This work was presented at the Symposium on Non-HIV Antivirals at the 224th American Chemical Society Meeting at Boston, MA, August 1822, 2002.)
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- Medicinal Research Reviews, 2003, v. 23, n. 3, p. 253, doi. 10.1002/med.10035
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New anti-HIV agents and targets.
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- Medicinal Research Reviews, 2002, v. 22, n. 6, p. 531, doi. 10.1002/med.10021
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Current lead natural products for the chemotherapy of human immunodeficiency virus (HIV) infection.
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- Medicinal Research Reviews, 2000, v. 20, n. 5, p. 323, doi. 10.1002/1098-1128(200009)20:5<323::AID-MED1>3.0.CO;2-A
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The HIV-1 Reverse Transcription (RT) Process as Target for RT Inhibitors.
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- Medicinal Research Reviews, 2000, v. 20, n. 2, p. 129, doi. 10.1002/(SICI)1098-1128(200003)20:2<129::AID-MED2>3.0.CO;2-A
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Non-nucleoside reverse transcriptase inhibitors (NNRTIs) for the treatment of human immunodeficiency virus type 1 (HIV-1) infections: Strategies to overcome drug resistance development.
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- Medicinal Research Reviews, 1996, v. 16, n. 2, p. 125, doi. 10.1002/(SICI)1098-1128(199603)16:2<125::AID-MED1>3.0.CO;2-2
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HIV-1-specific RT inhibitors: Highly selective inhibitors of human immunodeficiency virus type 1 that are specifically targeted at the viral reverse transcriptase.
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- Medicinal Research Reviews, 1993, v. 13, n. 3, p. 229, doi. 10.1002/med.2610130303
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Discovery of piperidine-substituted thiazolo[5,4-d]pyrimidine derivatives as potent and orally bioavailable HIV-1 non-nucleoside reverse transcriptase inhibitors.
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- Communications Chemistry, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42004-019-0174-8
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Enfuvirtide: A Viewpoint by Erik De Clercq.
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- Drugs, 2003, v. 63, n. 24, p. 2767, doi. 10.2165/00003495-200363240-00006
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Emtricitabine: A Viewpoint by Erik De Clercq.
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- Drugs, 2003, v. 63, n. 22, p. 2425, doi. 10.2165/00003495-200363220-00005
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Antimicrobial and Cytotoxic Activities of Turbinaria conoides (J.Agardh) Kuetz.
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- Iranian Journal of Pharmaceutical Research, 2010, v. 9, n. 4, p. 411
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Synthesis, Characterization and in Vitro Study of the Cytostatic and Antiviral Activity of New Polymeric Silver(I) Complexes with Ribbon Structures Derived from the Conjugated Heterocyclic Thioamide 2-Mercapto-3,4,5,6-tetra- hydropyrimidine.
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- European Journal of Inorganic Chemistry, 2004, v. 2004, n. 7, p. 1420
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The development of BVDU: An odyssey.
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- Antiviral Chemistry & Chemotherapy, 2023, p. 1, doi. 10.1177/20402066231152971
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The development of BVDU: An odyssey.
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- Antiviral Chemistry & Chemotherapy, 2023, v. 31, p. 1, doi. 10.1177/20402066231152971
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Reflections on the Rega Institute for Medical Research, at the fiftieth anniversary of the Rega Stichting vzw (Rega Instituut vzw, Rega Foundation).
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- Antiviral Chemistry & Chemotherapy, 2022, p. 1, doi. 10.1177/20402066221129979
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Effect of (E)-5-(2-Bromovinyl)-2′-deoxyuridine on the Growth and Viral Capsid Antigen Expression of Epstein-Barr Virus-Associated Tumor (B-95-8) Cells Transplanted to Nude Mice.
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- Proceedings of the Society for Experimental Biology & Medicine, 1985, v. 178, n. 4, p. 616, doi. 10.3181/00379727-178-42051
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Failure of Athymic-Nude Mice Sensitized with Bacillus Calmette-Guérin to Produce Interferon in Response to Purified Protein Derivative.
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- Proceedings of the Society for Experimental Biology & Medicine, 1983, v. 172, n. 2, p. 260, doi. 10.3181/00379727-172-41556
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Antiviral and Anticellular Activities of Human and Murine Type I and Type II Interferons in Human Cells Monosomic, Disomic, and Trisomic for Chromosome 21.
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- Proceedings of the Society for Experimental Biology & Medicine, 1982, v. 170, n. 1, p. 103, doi. 10.3181/00379727-170-41405
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Neutralization of Interferon Activity in Homologous and Heterologous Cells with Homologous and Heterologous Antibody.
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- Proceedings of the Society for Experimental Biology & Medicine, 1980, v. 165, n. 1, p. 161, doi. 10.3181/00379727-165-40953
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Moloney Sarcoma Virus-Induced Tumors in Mice: Inhibition or Stimulation by (Poly rI)·(Poly rC)<sup>1</sup>.
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- Proceedings of the Society for Experimental Biology & Medicine, 1971, v. 137, n. 2, p. 590, doi. 10.3181/00379727-137-35627
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Discovery of Novel Amino Acids (Analogues)-Substituted Thiophene[3,2- d ]pyrimidine Derivatives as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors: Design, Synthesis, and Biological Evaluation.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 16, p. 9028, doi. 10.3390/ijms25169028
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Covalently Targeted Highly Conserved Tyr318 to Improve the Drug Resistance Profiles of HIV-1 NNRTIs: A Proof-of-Concept Study.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 2, p. 1215, doi. 10.3390/ijms24021215
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Mycophenolate mofetil inhibits the development of Coxsackie B3-virus-induced myocarditis in mice.
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- BMC Microbiology, 2003, v. 3, p. 25, doi. 10.1186/1471-2180-3-25
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Pyridazines 92. Synthesis of dialkyldipyridazinodiazepinones as potential HIV-1 reverse transcriptase inhibitors.
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- Journal of Heterocyclic Chemistry, 2001, v. 38, n. 1, p. 125, doi. 10.1002/jhet.5570380117
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Synthesis of 2-carbamoylmethyl-6-β-D-ribofuranosylpyridine with the aid of a Pd(0)-catalyzed reaction.
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- Journal of Heterocyclic Chemistry, 1993, v. 30, n. 5, p. 1245, doi. 10.1002/jhet.5570300513
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3′-(1,2,3-Triazol-1-yl)-2′,3′-dideoxythymidine and 3′-(1,2,3-triazol-1-yl)-2′,3′-dideoxyuridine.
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- Journal of Heterocyclic Chemistry, 1989, v. 26, n. 6, p. 1635, doi. 10.1002/jhet.5570260624
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The Effect of HBV Therapy on Glycemic Control in HBV‐Infected Patients With Diabetes: A 90‐day Multicenter Study.
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- Journal of Medical Virology, 2025, v. 97, n. 2, p. 1, doi. 10.1002/jmv.70185
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Synthesis and Biological Activities of C (5)-N-Spin-Labeled Uridines and Related Derivatives.
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- Helvetica Chimica Acta, 1983, v. 66, n. 2, p. 534, doi. 10.1002/hlca.19830660214
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New synthesis and anti-HIV and antiviral properties of 3-arylsulfonyl derivatives of 4-ydroxycoumarin and 4-hydroxyquinolone.
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- Pharmaceutical Chemistry Journal, 2008, v. 42, n. 5, p. 265, doi. 10.1007/s11094-008-0103-0
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Effects of topical and subconjunctival cidofovir (HPMPC) in an animal model.
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- Current Eye Research, 1998, v. 17, n. 6, p. 560, doi. 10.1080/02713689808951228
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