Works matching AU Wiebe, Leonard I.
Results: 46
Effect of acyclovir on the uptake of <sup>131</sup> I-labelled 1-(2′fluoro-2′-deoxy-βD-D-arabinofuranosyl)-5-lodouracil in herpes infected cells.
- Published in:
- Journal of Medical Virology, 1987, v. 22, n. 2, p. 183, doi. 10.1002/jmv.1890220210
- By:
- Publication type:
- Article
Dose-dependent pharmacokinetics of 1-(2-Deoxy-β-D- ribofuranosyl)-2,4-difluoro-5-iodobenzene: A potential mimic of 5-iodo-2'-deoxyuridine.
- Published in:
- Biopharmaceutics & Drug Disposition, 2003, v. 24, n. 9, p. 385, doi. 10.1002/bdd.375
- By:
- Publication type:
- Article
Pharmacokinetics and metabolism of the novel synthetic C-nucleoside, 1-(2-deoxy- β-D-ribofuranosyl)-2,4-difluoro- 5-iodobenzene: a potential mimic of 5-iodo-2′-deoxyuridine.
- Published in:
- Biopharmaceutics & Drug Disposition, 2002, v. 23, n. 3, p. 105, doi. 10.1002/bdd.301
- By:
- Publication type:
- Article
Synthesis and Biological Evaluation of Butanoate, Retinoate, and Bis(2,2,2-trichloroethyl)phosphate Derivatives of 5-Fluoro-2′-deoxyuridine and 2′,5-Difluoro-2′-deoxyuridine as Potential Dual Action Anticancer Prodrugs.
- Published in:
- Archiv der Pharmazie, 1999, v. 332, n. 8, p. 286, doi. 10.1002/(SICI)1521-4184(19998)332:8<286::AID-ARDP286>3.0.CO;2-9
- By:
- Publication type:
- Article
Synthesis and Antiviral Activity of 5-Ethyl-5-halo-6-alkoxy-(or Azido)-5,6-dihydro-2′-deoxyuridine Diastereomers as Potential Prodrugs to 5-Ethyl-2′-deoxyuridine.
- Published in:
- Archiv der Pharmazie, 1997, v. 330, n. 8, p. 259, doi. 10.1002/ardp.19973300806
- By:
- Publication type:
- Article
Synthesis and Antifungal Activities of Myristic Acid Analogs.
- Published in:
- Archiv der Pharmazie, 1996, v. 329, n. 11, p. 475, doi. 10.1002/ardp.19963291102
- By:
- Publication type:
- Article
Syntheses of 1-[(2-Hydroxyethoxy)methyl]- and 1-[(1,3-Dihydroxy-2-Propoxy)methyl]- Derivatives of 5-Substituted-2,4-difluorobenzene: Unnatural Acyclo Thymidine Mimics for Evaluation as Anticancer and Antiviral Agents.
- Published in:
- Nucleosides, Nucleotides & Nucleic Acids, 2000, v. 19, n. 9, p. 1397, doi. 10.1080/15257770008033850
- By:
- Publication type:
- Article
A Simple Computational Tool for Accurate, Quantitative Prediction of One-Electron Reduction Potentials of Hypoxia-Activated Tirapazamine Analogues.
- Published in:
- Journal of Pharmacy & Pharmaceutical Sciences, 2020, v. 23, p. 231, doi. 10.18433/jpps30602
- By:
- Publication type:
- Article
A Simple Computational Tool for Accurate, Quantitative Prediction of One-Electron Reduction Potentials of Hypoxia-Activated Tirapazamine Analogues.
- Published in:
- 2020
- By:
- Publication type:
- journal article
Positron Emission Tomography (PET) and Pharmacokinetics: Classical Blood Sampling Versus Image-Derived Analysis of [18F]FAZA and [18F]FDG in a Murine Tumor Bearing Model.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Electrophysiological characterization of a recombinant human Na<sup>+</sup>-coupled nucleoside transporter (hCNT1) produced in Xenopus oocytes.
- Published in:
- Journal of Physiology, 2004, v. 558, n. 3, p. 807, doi. 10.1113/jphysiol.2004.068189
- By:
- Publication type:
- Article
<sup>18</sup>F-FESB: synthesis and automated radiofluorination of a novel <sup>18</sup>F-labeled pet tracer for β-amyloid plaques.
- Published in:
- Journal of Labelled Compounds & Radiopharmaceuticals, 2005, v. 48, n. 13, p. 983, doi. 10.1002/jlcr.1011
- By:
- Publication type:
- Article
CycloSaligenyl Pronucleotides of 5-Iodo and 5-Trifluoromethyl-1-(2-deoxy-β-D-ribofuranosyl)-2,4-difluorobenzene Mimics of Thymidine:‡ Synthesis and Evaluation of this Pronucleotide Monophosphate Delivery System for Compounds with Potential Anticancer Activity#
- Published in:
- Nucleosides, Nucleotides & Nucleic Acids, 2003, v. 22, n. 12, p. 2121, doi. 10.1081/NCN-120026634
- By:
- Publication type:
- Article
Synthesis and Biological Evaluation of Iodoglucoazomycin (I-GAZ), an Azomycin-Glucose Adduct with Putative Applications in Diagnostic Imaging and Radiotherapy of Hypoxic Tumors.
- Published in:
- ChemMedChem, 2016, v. 11, n. 15, p. 1638, doi. 10.1002/cmdc.201600213
- By:
- Publication type:
- Article
Synthesis of [ 18 F]F-γ-T-3, a Redox-Silent γ-Tocotrienol (γ-T-3) Vitamin E Analogue for Image-Based In Vivo Studies of Vitamin E Biodistribution and Dynamics.
- Published in:
- Molecules, 2020, v. 25, n. 23, p. 5700, doi. 10.3390/molecules25235700
- By:
- Publication type:
- Article
654. Targeting Adenoviral Vectors for Use in Breast Cancer Gene Therapy.
- Published in:
- Molecular Therapy, 2006, v. 13, p. S252, doi. 10.1016/j.ymthe.2006.08.730
- By:
- Publication type:
- Article
Synthesis and Preliminary Evaluation of an ASGPr-Targeted Polycationic β -Cyclodextrin Carrier for Nucleosides and Nucleotides.
- Published in:
- Pharmaceutics, 2024, v. 16, n. 3, p. 323, doi. 10.3390/pharmaceutics16030323
- By:
- Publication type:
- Article
Radiation Dosimetry of Theragnostic Pairs for Isotopes of Iodine in IAZA.
- Published in:
- Pharmaceutics, 2022, v. 14, n. 8, p. 1655, doi. 10.3390/pharmaceutics14081655
- By:
- Publication type:
- Article
Improved Formulation of 224 Ra-Labeled Calcium Carbonate Microparticles by Surface Layer Encapsulation and Addition of EDTMP.
- Published in:
- Pharmaceutics, 2021, v. 13, n. 5, p. 634, doi. 10.3390/pharmaceutics13050634
- By:
- Publication type:
- Article
Pharmacokinetics and Scintigraphic Imaging of the Hypoxia-Imaging Agent [<sup>123</sup>I]IAZA in Healthy Adults Following Exercise-Based Cardiac Stress.
- Published in:
- Pharmaceutics, 2018, v. 10, n. 1, p. 25, doi. 10.3390/pharmaceutics10010025
- By:
- Publication type:
- Article
Development of [131I]I-EOE-TPZ and [131I]I-EOE-TPZMO: Novel Tirapazamine (TPZ)-Based Radioiodinated Pharmaceuticals for Application in Theranostic Management of Hypoxia.
- Published in:
- Pharmaceuticals (14248247), 2019, v. 12, n. 1, p. 3, doi. 10.3390/ph12010003
- By:
- Publication type:
- Article
Synthesis of 1-(2-deoxy-β- D-ribofuranosyl)-2,4- difluoro-5-(2-halo-1-hydroxyethyl)benzenes and related derivatives: 'thymine replacement' analogs of deoxythymidine for evaluation as antiviral and anticancer agents.
- Published in:
- Drug Development Research, 2001, v. 52, n. 3, p. 492, doi. 10.1002/ddr.1151
- By:
- Publication type:
- Article
Synthesis and radioiodination of 3-( E)-(2-iodovinyl)-N-acetyl-4-cysteaminylphenol, a putative tyrosinase substrate for imaging neural crest tumours.
- Published in:
- Journal of Labelled Compounds & Radiopharmaceuticals, 1998, v. 41, n. 5, p. 355, doi. 10.1002/(SICI)1099-1344(199805)41:5<355::AID-JLCR88>3.0.CO;2-K
- By:
- Publication type:
- Article
Syntheses of [2-<sup>2</sup>H]-5-ethynyl-1-(β-D-ribofuranosyl)imidazole-4-carboxamide and 5-ethynyl-1-([5-<sup>3</sup>H]-β-D-ribofuranosyl)imidazole-4-carboxamide (EICAR).
- Published in:
- Journal of Labelled Compounds & Radiopharmaceuticals, 1996, v. 38, n. 9, p. 809, doi. 10.1002/(SICI)1099-1344(199609)38:9<809::AID-JLCR899>3.0.CO;2-0
- By:
- Publication type:
- Article
An efficient, high specific activity radioiodination of 5-(1-hydroxy/methoxy-2-iodoethyl)-2′-deoxyuridine by isotope exchange labelling in pivalic acid melt.
- Published in:
- Journal of Labelled Compounds & Radiopharmaceuticals, 1990, v. 28, n. 3, p. 247, doi. 10.1002/jlcr.2580280302
- By:
- Publication type:
- Article
Synthesis of [5-<sup>14</sup>C]-1,1,12,12-tetraethoxy-4,9-diazadodecane dinitrate.
- Published in:
- Journal of Labelled Compounds & Radiopharmaceuticals, 1989, v. 27, n. 4, p. 449, doi. 10.1002/jlcr.2580270412
- By:
- Publication type:
- Article
An improved synthesis of [1-<sup>14</sup>C]-labelled 2-butynedioic acid, succinic acid and succinyl chloride.
- Published in:
- Journal of Labelled Compounds & Radiopharmaceuticals, 1988, v. 25, n. 12, p. 1325, doi. 10.1002/jlcr.2580251206
- By:
- Publication type:
- Article
Synthesis of [2-<sup>14</sup>C]-1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-fluoro(chloro)uracil.
- Published in:
- Journal of Labelled Compounds & Radiopharmaceuticals, 1987, v. 24, n. 9, p. 1107, doi. 10.1002/jlcr.2580240912
- By:
- Publication type:
- Article
Initial results of hypoxia imaging using 1-α-D-(5-deoxy-5-[<sup>18</sup>F]-fluoroarabinofuranosyl)-2-nitroimidazole (<sup>18</sup>F-FAZA).
- Published in:
- European Journal of Nuclear Medicine & Molecular Imaging, 2009, v. 36, n. 10, p. 1565, doi. 10.1007/s00259-009-1154-5
- By:
- Publication type:
- Article
Radiolabeling with Organomercury Compounds: Part 2. High Specific Activity Synthesis of Iodine-125 and Iodine-131-6-Iodocholest-5-en-3β-ol and Its Tissue Distribution in Rats.
- Published in:
- Journal of Nuclear Medicine, 1986, v. 27, n. 7, p. 1165
- By:
- Publication type:
- Article
Aziridination of the uracil 5,6-olefinic bond of 3- N-3′,5′-Di- O-tribenzoyl-5-vinyl-2′-deoxyuridine.
- Published in:
- Journal of Heterocyclic Chemistry, 1991, v. 28, n. 5, p. 1467, doi. 10.1002/jhet.5570280549
- By:
- Publication type:
- Article
Synthesis of brain-targeted 5-iodo-, 5-vinyl- and ( E)-5-(2-iodovinyl)-2′-deoxyuridines coupled to a dihydropyridine ⇌ pyridinium salt redox chemical delivery system.
- Published in:
- Journal of Heterocyclic Chemistry, 1991, v. 28, n. 3, p. 711, doi. 10.1002/jhet.5570280327
- By:
- Publication type:
- Article
Design and synthesis of the 3′-aminocarbonylamino, aminothiocarbonylamino and N-(Hydroxy)guanidinyl derivatives of thymidine as potential anti-HIV agents.
- Published in:
- Journal of Heterocyclic Chemistry, 1991, v. 28, n. 3, p. 807, doi. 10.1002/jhet.5570280346
- By:
- Publication type:
- Article
Synthesis and biological evaluation of 5-(1-alkoxy-2-haloethyl)-2′-deoxyuridines and related uracil analogues.
- Published in:
- Journal of Heterocyclic Chemistry, 1991, v. 28, n. 2, p. 237, doi. 10.1002/jhet.5570280206
- By:
- Publication type:
- Article
Reaction of 1-(2′,3′-epoxy-β- D-lyxofuranosyl)uracil with hydrogen fluoride. The unexpected formation of 1-(3′-fluoro-3′-deoxy-β- D-ribofuranosyl)uracil.
- Published in:
- Journal of Heterocyclic Chemistry, 1984, v. 21, n. 3, p. 773, doi. 10.1002/jhet.5570210327
- By:
- Publication type:
- Article
Labelling of Small Biomolecules Using Novel Technetium-99m Cores.
- Published in:
- Journal of Nuclear Medicine, 2008, v. 49, n. 11, p. 1901, doi. 10.2967/jnumed.108.054338
- By:
- Publication type:
- Article
Comparative Evaluation of Therapeutic Radiopharmaceuticals.
- Published in:
- Journal of Nuclear Medicine, 2008, v. 49, n. 11, p. 1900, doi. 10.2967/jnumed.108.054288
- By:
- Publication type:
- Article
Hypoxia-Specific Tumor Imaging with <sup>18</sup>F-Fluoroazomycin Arabinoside.
- Published in:
- Journal of Nuclear Medicine, 2005, v. 46, n. 1, p. 106
- By:
- Publication type:
- Article
FDG Metabolism: Quaecumque Sunt Vera….
- Published in:
- Journal of Nuclear Medicine, 2001, v. 42, n. 11, p. 1679
- By:
- Publication type:
- Article
Dosimetry Estimations for <sup>123</sup>I-IAZA in Healthy Volunteers.
- Published in:
- Journal of Nuclear Medicine, 2001, v. 42, n. 9, p. 1418
- By:
- Publication type:
- Article
Imaging Tumor Hypoxia and Tumor Perfusion.
- Published in:
- Journal of Nuclear Medicine, 1993, v. 34, n. 6, p. 885
- By:
- Publication type:
- Article
Measurement of PDT-Induced Hypoxia in Dunning Prostate Tumors by Iodine-123-Iodoazomycin Arabinoside.
- Published in:
- Journal of Nuclear Medicine, 1993, v. 34, n. 3, p. 405
- By:
- Publication type:
- Article
Radioiodinated 1-(5-Iodo-5-deoxy-β-D-arabinofuranosyl)-2-nitroimidazole (Iodoazomycin Arabinoside: IAZA): A Novel Marker of Tissue Hypoxia.
- Published in:
- Journal of Nuclear Medicine, 1991, v. 32, n. 9, p. 1764
- By:
- Publication type:
- Article
High Specific Activity [Samarium-153] EDTA for Imaging of Experimental Tumor Models.
- Published in:
- Journal of Nuclear Medicine, 1989, v. 30, n. 2, p. 202
- By:
- Publication type:
- Article
Synthesis of 5-(1-azido-2-haloethyl)arabinouridines.
- Published in:
- Journal of Heterocyclic Chemistry, 1997, v. 34, n. 4, p. 1369, doi. 10.1002/jhet.5570340445
- By:
- Publication type:
- Article
Synthesis and properties of 5-(1,2-dihaloethyl)-2′-deoxyuridines and related analogues.
- Published in:
- Journal of Heterocyclic Chemistry, 1991, v. 28, n. 8, p. 1917, doi. 10.1002/jhet.5570280819
- By:
- Publication type:
- Article