Title: Microwave-Assisted and Ultrasonic-Assisted Three-Component Heterocyclization of 4-Amino-5-carboxamido-1,2,3-triazole, Thiopyran-3-one-1,1-dioxide, and Aromatic Aldehydes.
Authors: Gladkov, Eugene S.; Desenko, Sergey M.; Konovalova, Irina S.; Groth, Ulrich; Shishkin, Oleg V.; Vashchenko, Elena V.; Chebanov, Valentin A.
Abstract: Three-component heterocyclization of 4-amino-5-carboxamido-1,2,3-triazole, thiopyran-3-one-1,1-dioxide, and aromatic aldehydes under ultrasonic and microwave irradiation was studied. Regardless of the reaction parameters, 5,6,7,9-tetrahydro-4 H-thiopyrano[3,2- d][1,2,3]triazolo[1,5- a]pyrimidine-8,8-dioxides were isolated as sole reaction products whose structures were proven with help of NMR data and X-ray analysis.
Subjects: HETEROCYCLIC compounds; MICROWAVES; RING formation (Chemistry); ULTRASONIC waves; TRIAZOLES; THIOPYRAN; AROMATIC aldehydes; NUCLEAR magnetic resonance spectroscopy
Publication: Journal of Heterocyclic Chemistry, 2013, Vol 50, pE189
ISSN: 0022-152X
Publication type: Academic Journal
DOI: 10.1002/jhet.1503

Microwave-Assisted and Ultrasonic-Assisted Three-Component Heterocyclization of 4-Amino-5-carboxamido-1,2,3-triazole, Thiopyran-3-one-1,1-dioxide, and Aromatic Aldehydes.

Gladkov, Eugene S.; Desenko, Sergey M.; Konovalova, Irina S.; Groth, Ulrich; Shishkin, Oleg V.; Vashchenko, Elena V.; Chebanov, Valentin A.