Works matching IS 00912700 AND DT 2016 AND VI 56 AND IP 4

Results: 19

The Evergreening of Biopharmaceuticals: Time to Defoliate.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 4, p. 383, doi. 10.1002/jcph.642

By:

Lehmann, David F.;
Wojnowicz, Sarabeth

Publication type:

Article

A thorough QTc study demonstrates that olmesartan medoxomil does not prolong the QTc interval.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 4, p. 484, doi. 10.1002/jcph.610

By:

Mendell, Jeanne;
Matsushima, Nobuko;
O'Reilly, Terry E.;
Lee, James

Publication type:

Article

Population pharmacokinetic and pharmacodynamic analyses from a 4-month intradose escalation and its subsequent 12-month dose titration studies for a human monoclonal anti-FGF23 antibody (KRN23) in adults with X-linked hypophosphatemia.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 4, p. 429, doi. 10.1002/jcph.611

By:

Zhang, Xiaoping;
Peyret, Thomas;
Gosselin, Nathalie H.;
Marier, J. F.;
Imel, Erik A.;
Carpenter, Thomas O.

Publication type:

Article

Cerebrospinal fluid concentrations of tenofovir and emtricitabine in the setting of HIV-1 protease inhibitor-based regimens.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 4, p. 492, doi. 10.1002/jcph.612

By:

Lahiri, Cecile D.;
Reed‐Walker, Kedria;
Sheth, Anandi N.;
Acosta, Edward P.;
Vunnava, Aswani;
Ofotokun, Ighovwerha

Publication type:

Article

The effect of quinidine, a strong P-glycoprotein inhibitor, on the pharmacokinetics and central nervous system distribution of naloxegol.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 4, p. 497, doi. 10.1002/jcph.613

By:

Bui, Khanh;
She, Fahua;
Zhou, Diansong;
Butler, Kathleen;
Al‐Huniti, Nidal;
Sostek, Mark

Publication type:

Article

Population plasma and urine pharmacokinetics of ivabradine and its active metabolite S18982 in healthy Korean volunteers.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 4, p. 439, doi. 10.1002/jcph.614

By:

Choi, Hee Youn;
Bae, Kyun‐Seop;
Cho, Sang‐Heon;
Ghim, Jong‐Lyul;
Choe, Sangmin;
Jung, Jin Ah;
Lim, Hyeong‐Seok

Publication type:

Article

Topical diclofenac does not affect the antiplatelet properties of aspirin as compared to the intermediate effects of oral diclofenac: A prospective, randomized, complete crossover study.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 4, p. 422, doi. 10.1002/jcph.615

By:

Rowcliffe, M.;
Nezami, B.;
Westphal, E. S.;
Rainka, M.;
Janda, M.;
Bates, V.;
Gengo, F.

Publication type:

Article

Practical considerations to drug dosing in children with acute kidney injury.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 4, p. 399, doi. 10.1002/jcph.636

By:

Assadi, Farahnak;
Sharbaf, Fatemeh Ghane

Publication type:

Article

The Effect of Quinidine, a Strong P-Glycoprotein Inhibitor, on the Pharmacokinetics and Central Nervous System Distribution of Naloxegol.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 4, p. 506, doi. 10.1002/jcph.651

By:

Ruan, Xiulu

Publication type:

Article

In Memoriam: David A. Flockhart, 1952-2015.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 4, p. 509, doi. 10.1002/jcph.726

By:

Greenblatt, David J.;
Abernethy, Darrell R.

Publication type:

Article

Issue Information.

Published in:: Journal of Clinical Pharmacology, 2016, v. 56, n. 4, p. 375, doi. 10.1002/jcph.729
Publication type:: Article

Influence of kidney disease on drug disposition: An assessment of industry studies submitted to the FDA for new chemical entities 1999-2010.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 4, p. 390, doi. 10.1002/jcph.604

By:

Matzke, Gary R.;
Dowling, Thomas C.;
Marks, Samantha A.;
Murphy, John E.

Publication type:

Article

Impact of cytochrome P450 2C19 polymorphisms on the pharmacokinetics of tacrolimus when coadministered with voriconazole.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 4, p. 408, doi. 10.1002/jcph.605

By:

Imamura, Chiyo K.;
Furihata, Kenichi;
Okamoto, Shinichiro;
Tanigawara, Yusuke

Publication type:

Article

Pharmacokinetics of serelaxin in patients with severe renal impairment or end-stage renal disease requiring hemodialysis: A single-dose, open-label, parallel-group study.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 4, p. 474, doi. 10.1002/jcph.607

By:

Dahlke, Marion;
Halabi, Atef;
Canadi, Jasna;
Tsubouchi, Chiaki;
Machineni, Surendra;
Pang, Yinuo

Publication type:

Article

Platelet response to increased aspirin dose in patients with persistent platelet aggregation while treated with aspirin 81 mg.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 4, p. 414, doi. 10.1002/jcph.608

By:

Gengo, Fran;
Westphal, Erica S.;
Rainka, Michelle M.;
Janda, Maria;
Robson, Matthew J.;
Hourihane, J. Maurice;
Bates, Vernice

Publication type:

Article

Reply to: Letter to the Editor 'Effect of Quinidine, a Strong P-Glycoprotein Inhibitor, on the Pharmacokinetics and Central Nervous System Distribution of Naloxegol'.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 4, p. 508, doi. 10.1002/jcph.674

By:

Al‐Huniti, Nidal

Publication type:

Article

How close are PDE5 inhibitors to being successful in the treatment of BPH?

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 4, p. 381, doi. 10.1002/jcph.623

By:

Öztürk, Hakan

Publication type:

Article

Effects of UGT1A1 genotype on the pharmacokinetics, pharmacodynamics, and toxicities of belinostat administered by 48-hour continuous infusion in patients with cancer.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 4, p. 461, doi. 10.1002/jcph.625

By:

Goey, Andrew K. L.;
Sissung, Tristan M.;
Peer, Cody J.;
Trepel, Jane B.;
Lee, Min‐Jung;
Tomita, Yusuke;
Ehrlich, Sheryl;
Bryla, Christine;
Balasubramaniam, Sanjeeve;
Piekarz, Richard;
Steinberg, Seth M.;
Bates, Susan E.;
Figg, William D.

Publication type:

Article

UGT1A1 genotype-dependent dose adjustment of belinostat in patients with advanced cancers using population pharmacokinetic modeling and simulation.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 4, p. 450, doi. 10.1002/jcph.627

By:

Peer, Cody J.;
Goey, Andrew K. L.;
Sissung, Tristan M.;
Erlich, Sheryl;
Lee, Min‐Jung;
Tomita, Yusuke;
Trepel, Jane B.;
Piekarz, Richard;
Balasubramaniam, Sanjeeve;
Bates, Susan E.;
Figg, William D.

Publication type:

Article