Works matching IS 00912700 AND DT 2015 AND VI 55

Results: 203

CYP2C9 Involvement in ACT-453859 Metabolism.

Published in:

2015

By:

Géhin, Martine;
Dingemanse, Jasper;
Sidharta, Patricia N.

Publication type:

Letter to the Editor

First-in-Man Study of ACT-453859, a Potent CRTH2 Antagonist--Is the Metabolite Formation Influenced by a Polymorphic Enzyme?

Published in:

2015

By:

Srinivas, Nuggehally R.

Publication type:

Letter to the Editor

A Delphi Study Among Internal Medicine Clinicians to Determine Which Therapeutic Information Is Essential to Record in a Medical Record.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 12, p. 1415, doi. 10.1002/jcph.565

By:

van Unen, Robert J.;
Tichelaar, Jelle;
Nanayakkara, Prabath W.B.;
van Agtmael, Michiel A.;
Richir, Milan C.;
de Vries, Theo P.G.M.

Publication type:

Article

Food Effects on Abiraterone Pharmacokinetics in Healthy Subjects and Patients With Metastatic Castration-Resistant Prostate Cancer.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 12, p. 1406, doi. 10.1002/jcph.564

By:

Chi, Kim N.;
Spratlin, Jennifer;
Kollmannsberger, Christian;
North, Scott;
Pankras, Catherine;
Gonzalez, Martha;
Bernard, Apexa;
Stieltjes, Hans;
Peng, Lixian;
Jiao, James;
Acharya, Milin;
Kheoh, Thian;
Griffin, Thomas W.;
Yu, Margaret K.;
Chien, Caly;
Tran, Nam Phuong

Publication type:

Article

Evaluation of regional gastrointestinal absorption of edoxaban using the enterion capsule.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 11, p. 1286, doi. 10.1002/jcph.540

By:

Parasrampuria, Dolly A.;
Kanamaru, Taro;
Connor, Alyson;
Wilding, Ian;
Ogata, Koichiro;
Shimoto, Yoshimasa;
Kunitada, Satoshi

Publication type:

Article

Enzyme- and Transporter-Mediated Beverage- Drug Interactions: An Update on Fruit Juices and Green Tea.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 12, p. 1313, doi. 10.1002/jcph.563

By:

An, Guohua;
Mukker, Jatinder Kaur;
Derendorf, Hartmut;
Frye, Reginald F.

Publication type:

Article

Evaluation of CYP3A-Mediated Drug-Drug Interactions With Romidepsin in Patients With Advanced Cancer.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 12, p. 1378, doi. 10.1002/jcph.560

By:

Laille, Eric;
Patel, Manish;
Jones, Suzanne F.;
Burris, Howard A.;
Infante, Jeffrey;
Lemech, Charlotte;
Liu, Liangang;
Arkenau, Hendrik‐Tobias

Publication type:

Article

The Effects of a Low-Salt Diet on the Efficacy of Different Antihypertensive Drug Regimens.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 12, p. 1362, doi. 10.1002/jcph.559

By:

Wang, Jing;
Qiu, Bo;
Du, Jian‐Lin;
Deng, Song‐Bai;
Liu, Ya‐Jie;
She, Qiang

Publication type:

Article

Dried Blood Spot Analysis for Therapeutic Drug Monitoring of Pazopanib.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 12, p. 1344, doi. 10.1002/jcph.558

By:

de Wit, Djoeke;
den Hartigh, Jan;
Gelderblom, Hans;
Qian, Yanwen;
den Hollander, Margret;
Verheul, Henk;
Guchelaar, Henk‐Jan;
van Erp, Nielka P.

Publication type:

Article

Quinine as a Potential Tracer for Medication Adherence: A Pharmacokinetic and Pharmacodynamic Assessment of Quinine Alone and in Combination With Oxycodone in Humans.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 12, p. 1332, doi. 10.1002/jcph.557

By:

Babalonis, Shanna;
Hampson, Aidan J.;
Lofwall, Michelle R.;
Nuzzo, Paul A.;
Walsh, Sharon L.

Publication type:

Article

Evaluation of Disease-Mediated Therapeutic Protein-Drug Interactions Between an Anti-Interleukin-6 Monoclonal Antibody (Sirukumab) and Cytochrome P450 Activities in a Phase 1 Study in Patients With Rheumatoid Arthritis Using a Cocktail Approach.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 12, p. 1386, doi. 10.1002/jcph.561

By:

Zhuang, Yanli;
de Vries, Dick E.;
Xu, Zhenhua;
Marciniak, Stanley J.;
Chen, Dion;
Leon, Francisco;
Davis, Hugh M.;
Zhou, Honghui

Publication type:

Article

Intranasal Administration of Crushed ALO-02 (Extended-Release Oxycodone With Sequestered Naltrexone): A Randomized, Controlled Abuse-Potential Study in Nondependent Recreational Opioid Users.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 12, p. 1351, doi. 10.1002/jcph.552

By:

Setnik, Beatrice;
Bramson, Candace;
Bass, Almasa;
Levy‐Cooperman, Naama;
Malhotra, Bimal;
Matschke, Kyle;
Sommerville, Kenneth W.;
Wolfram, Gernot;
Geoffroy, Pierre

Publication type:

Article

An Open-Label, Phase 1 Study to Evaluate the Effects of Hepatic Impairment on Edoxaban Pharmacokinetics and Pharmacodynamics.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 12, p. 1395, doi. 10.1002/jcph.550

By:

Mendell, Jeanne;
Johnson, Lisa;
Chen, Shuquan

Publication type:

Article

Preserved Pharmacokinetic Exposure and Distinct Glycemic Effects of Insulin Degludec and Liraglutide in IDegLira, a Fixed-Ratio Combination Therapy.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 12, p. 1369, doi. 10.1002/jcph.549

By:

Kapitza, Christoph;
Bode, Bruce;
Ingwersen, Steen Hvass;
Jacobsen, Lisbeth Vestergård;
Poulsen, Pernille

Publication type:

Article

Issue Information.

Published in:: 2015
Publication type:: Other

Evaluation of the effect of food and gastric pH on the single-dose pharmacokinetics of cabozantinib in healthy adult subjects.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 11, p. 1293, doi. 10.1002/jcph.526

By:

Nguyen, Linh;
Holland, Jaymes;
Mamelok, Richard;
Laberge, Marie‐Kristine;
Grenier, Julie;
Swearingen, Dennis;
Armas, Danielle;
Lacy, Steven

Publication type:

Article

Pharmacodynamics of Norepinephrine Reuptake Inhibition: Modeling the Peripheral and Central Effects of Atomoxetine, Duloxetine, and Edivoxetine on the Biomarker 3,4-Dihydroxyphenylglycol in Humans.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 12, p. 1422, doi. 10.1002/jcph.551

By:

Kielbasa, William;
Lobo, Evelyn

Publication type:

Article

Population pharmacokinetics of edoxaban and its main metabolite in a dedicated renal impairment study.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 11, p. 1268, doi. 10.1002/jcph.541

By:

Jönsson, Siv;
Simonsson, Ulrika S. H.;
Miller, Raymond;
Karlsson, Mats O.

Publication type:

Article

Quantification of the impact of enzyme-inducing antiepileptic drugs on irinotecan pharmacokinetics and SN-38 exposure.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 11, p. 1303, doi. 10.1002/jcph.543

By:

Berg, Alexander K.;
Buckner, Jan C.;
Galanis, Evanthia;
Jaeckle, Kurt A.;
Ames, Matthew M.;
Reid, Joel M.

Publication type:

Article

Population pharmacokinetic modeling of quetiapine after administration of seroquel and seroquel XR formulations to Western and Chinese patients with schizophrenia, schizoaffective disorder, or bipolar disorder.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 11, p. 1248, doi. 10.1002/jcph.544

By:

Zhou, Diansong;
Bui, Khanh H.;
Li, Jianguo;
Al‐Huniti, Nidal

Publication type:

Article

Clinical pharmacology, creating current and future success in drug development.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 11, p. 1193, doi. 10.1002/jcph.547

By:

Rogge, Mark C.;
Dresser, Mark;
Fossler, Michael;
Heald, Donald;
Stoch, S. Aubrey;
Vanevski, Konstantina M.;
Bello, Akintunde

Publication type:

Article

Markov model for characterizing neuropsychologic impairment and Monte Carlo simulation for optimizing efavirenz therapy.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 11, p. 1229, doi. 10.1002/jcph.533

By:

Bisaso, Kuteesa R.;
Mukonzo, Jackson K.;
Ette, Ene I.

Publication type:

Article

Newer multiple sclerosis drugs and disability scores-are key data analyses missing?

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 11, p. 1218, doi. 10.1002/jcph.535

By:

Avasarala, Jagannadha R.

Publication type:

Article

Pharmacometrics-guided drug development of antihyperhidrosis agents.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 11, p. 1256, doi. 10.1002/jcph.536

By:

Mehrotra, Shailly;
Schmith, Virginia D.;
Dumitrescu, Teodora Pene;
Gobburu, Jogarao

Publication type:

Article

Tacrolimus 0.03% ointment in labial discoid lupus erythematosus: A randomized, controlled clinical trial.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 11, p. 1221, doi. 10.1002/jcph.537

By:

Wang, Xiangjian;
Zhang, Lin;
Luo, Jingjing;
Wu, Zhongting;
Mei, Yingying;
Wang, Yuhong;
Li, Xiaoying;
Wang, Wanchun;
Zhou, Hongmei

Publication type:

Article

Population pharmacokinetic-pharmacodynamic modeling of omecamtiv mecarbil, a cardiac myosin activator, in healthy volunteers and patients with stable heart failure.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 11, p. 1236, doi. 10.1002/jcph.538

By:

Vu, Thuy;
Ma, Peiming;
Xiao, Jim J.;
Wang, Yow‐Ming C.;
Malik, Fady I.;
Chow, Andrew T.

Publication type:

Article

Weighing the adverse cardiac effects of fluoroquinolones: A risk perspective.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 11, p. 1198, doi. 10.1002/jcph.553

By:

Mehrzad, Raman;
Barza, Michael

Publication type:

Article

Quantitative clinical pharmacology for size and age scaling in pediatric drug development: A systematic review.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 11, p. 1207, doi. 10.1002/jcph.555

By:

Samant, Tanay S.;
Mangal, Naveen;
Lukacova, Viera;
Schmidt, Stephan

Publication type:

Article

Comparison of erythropoietin resistance in hemodialysis patients using calcitriol, cinacalcet, or paricalcitol.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 11, p. 1280, doi. 10.1002/jcph.556

By:

Afsar, Baris;
Agca, Erhan;
Turk, Suleyman

Publication type:

Article

Pharmacokinetics of bound and unbound telaprevir in cirrhotic patients with moderate and severe hepatic impairment.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 10, p. 1147, doi. 10.1002/jcph.545

By:

Ouwerkerk‐Mahadevan, Sivi;
Halabi, Atef;
Cieslarová, Blanka;
Aerts, Indra;
Witek, James;
Van Solingen‐Ristea, Rodica;
Luo, Donghan

Publication type:

Article

Population pharmacokinetics modeling and analysis of foretinib in adult patients with advanced solid tumors.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 10, p. 1184, doi. 10.1002/jcph.546

By:

Singh, Rajendra P.;
Patel, Bela;
Kallender, Howard;
Ottesen, Lone H.;
Adams, Laurel M.;
Cox, Donna S.

Publication type:

Article

Hydroxyurea-mediated release of nitric oxide in myeloproliferative neoplasms patients: Effects on platelet-leukocyte interaction.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 10, p. 1125, doi. 10.1002/jcph.548

By:

Gumiero, Daniela;
Di Gennaro, Leonardo;
Nicolazzi, Maria Anna;
Landolfi, Raffaele

Publication type:

Article

Pharmacokinetic and pharmacodynamic interactions between palifermin and heparin.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 10, p. 1109, doi. 10.1002/jcph.516

By:

Yang, Bing‐Bing;
Gillespie, Brad;
Smith, Brian;
Smith, William;
Lissmats, Agneta;
Rudebeck, Mattias;
Kullenberg, Torbjörn;
Olsson, Birgitta

Publication type:

Article

Effects of OM-85 BV in patients with chronic obstructive pulmonary disease: A systematic review and meta-analysis.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 10, p. 1086, doi. 10.1002/jcph.518

By:

Pan, Lei;
Jiang, Xue‐Ge;
Guo, Jun;
Tian, Yuan;
Liu, Chang‐Ting

Publication type:

Article

Long-term cardiac safety and tolerability of fingolimod in multiple sclerosis: A postmarketing study.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 10, p. 1131, doi. 10.1002/jcph.519

By:

Paolicelli, Damiano;
Manni, Alessia;
Direnzo, Vita;
D'Onghia, Mariangela;
Tortorella, Carla;
Zoccolella, Stefano;
Trojano, Maria

Publication type:

Article

CYP2D6 predicted metabolizer status and safety in adult patients with attention-deficit hyperactivity disorder participating in a large placebo-controlled atomoxetine maintenance of response clinical trial.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 10, p. 1167, doi. 10.1002/jcph.530

By:

Fijal, Bonnie A.;
Guo, Yingying;
Li, Si G.;
Ahl, Jonna;
Goto, Taro;
Tanaka, Yoko;
Nisenbaum, Laura K.;
Upadhyaya, Himanshu P.

Publication type:

Article

Effects of the orexin receptor antagonist suvorexant on respiration during sleep in healthy subjects.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 10, p. 1093, doi. 10.1002/jcph.523

By:

Uemura, Naoto;
McCrea, Jacqueline;
Sun, Hong;
Donikyan, Mardik;
Zammit, Gary;
Liu, Rong;
Louridas, Bonnie;
Marsilio, Sabrina;
Lines, Christopher;
Troyer, Matthew D.;
Wagner, John

Publication type:

Article

Issue Information.

Published in:: 2015
Publication type:: Other

A proposal for scientific framework enabling specific population drug dosing recommendations.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 10, p. 1073, doi. 10.1002/jcph.579

By:

Jadhav, Pravin R.;
Cook, Jack;
Sinha, Vikram;
Zhao, Ping;
Rostami‐Hodjegan, Amin;
Sahasrabudhe, Vaishali;
Stockbridge, Norman;
Powell, J. Robert

Publication type:

Article

Antiretroviral therapy-induced toxicity is associated with increased mRNA expression of telomerase.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 10, p. 1119, doi. 10.1002/jcph.520

By:

Li, Min;
Foli, Yram;
Amakye, Nana Y.;
Klein, Taline;
Selvaraj, Shanmugapriya;
Lu, Lingeng;
Paintsil, Elijah

Publication type:

Article

Steady-state pharmacokinetics and bioavailability of immediate-release and extended-release formulations of lamotrigine in elderly epilepsy patients: Use of stable isotope methodology.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 10, p. 1101, doi. 10.1002/jcph.522

By:

Polepally, Akshanth R.;
Remmel, Rory P.;
Brundage, Richard C.;
Leppik, Ilo E.;
Rarick, John O.;
Ramsay, R. Eugene;
Birnbaum, Angela K.

Publication type:

Article

Small-molecule compounds exhibiting target-mediated drug disposition - A case example of ABT-384.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 10, p. 1079, doi. 10.1002/jcph.531

By:

An, Guohua;
Liu, Wei;
Dutta, Sandeep

Publication type:

Article

Effect of ceralifimod (ONO-4641) on lymphocytes and cardiac function: Randomized, double-blind, placebo-controlled trial with an open-label fingolimod arm.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 9, p. 1051, doi. 10.1002/jcph.513

By:

Krösser, Sonja;
Wolna, Peter;
Fischer, Tanya Z.;
Boschert, Ursula;
Stoltz, Randall;
Zhou, Meijian;
Darpo, Borje

Publication type:

Article

Assessment of hemoglobin responsiveness to epoetin alfa in patients on hemodialysis using a population pharmacokinetic pharmacodynamic model.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 10, p. 1157, doi. 10.1002/jcph.527

By:

Wu, Liviawati;
Mould, Diane R.;
Perez Ruixo, Juan Jose;
Doshi, Sameer

Publication type:

Article

Comparison of different QT interval correction methods for heart rate and QT beat-to-beat method in a thorough QT study of triple monoamine reuptake inhibitor BMS-820836.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 10, p. 1137, doi. 10.1002/jcph.528

By:

Zheng, Ming;
Burt, David;
Chan, Wai;
Hawthorne, Dara;
Gasior, Maciej;
Bhagwagar, Zubin;
Keswani, Sanjay;
AbuTarif, Malaz;
Bertz, Richard

Publication type:

Article

Pharmacokinetic (PK) drug interaction studies of cabozantinib: Effect of CYP3A inducer rifampin and inhibitor ketoconazole on cabozantinib plasma PK and effect of cabozantinib on CYP2C8 probe substrate rosiglitazone plasma PK.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 9, p. 1012, doi. 10.1002/jcph.510

By:

Nguyen, Linh;
Holland, Jaymes;
Miles, Dale;
Engel, Caroline;
Benrimoh, Natacha;
O'Reilly, Terry;
Lacy, Steven

Publication type:

Article

Pharmacokinetics of hepatitis C virus NS5A inhibitor JNJ-56914845 (GSK2336805) in subjects with hepatic impairment.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 9, p. 1042, doi. 10.1002/jcph.512

By:

Adkison, Kimberly K.;
Gan, Jianjun;
Elko‐Simms, Lucinda;
Gardner, Stephen;
Dumont, Etienne;
Jones, Lori S.;
Saunders, Joanne;
Marbury, Thomas;
Smith, William;
Berg, Jolene;
Galloway, Christopher;
Stump, Patrick J.

Publication type:

Article

Predicting neonatal pharmacokinetics from prior data using population pharmacokinetic modeling.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 10, p. 1175, doi. 10.1002/jcph.524

By:

Wang, Jian;
Edginton, Andrea N.;
Avant, Debbie;
Burckart, Gilbert J.

Publication type:

Article

Comparison of the pharmacokinetics of an oral extended-release capsule formulation of carbidopa-levodopa (IPX066) with immediate-release carbidopa-levodopa (Sinemet®), sustained-release carbidopa-levodopa (Sinemet® CR), and carbidopa-levodopa-entacapone (Stalevo®)

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 9, p. 995, doi. 10.1002/jcph.514

By:

Hsu, Ann;
Yao, Hsuan‐Ming;
Gupta, Suneel;
Modi, Nishit B.

Publication type:

Article

Effect of multiple intravenous doses of lanicemine (AZD6765) on the pharmacokinetics of midazolam in healthy subjects.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 9, p. 1024, doi. 10.1002/jcph.515

By:

Bui, Khanh H.;
Zhou, Diansong;
Agbo, Felix;
Guo, Jian

Publication type:

Article