Works matching IS 00912700 AND DT 2014 AND VI 54 AND IP 5

Results: 16

Safety, tolerability, pharmacokinetics, and pharmacodynamics of the novel γ-secretase modulator, E2212, in healthy human subjects.

Published in:

2014

By:

Yu, Yanke;
Logovinsky, Veronika;
Schuck, Edgar;
Kaplow, June;
Chang, Min-kun;
Miyagawa, Takehiko;
Wong, Nancy;
Ferry, Jim

Publication type:

Journal Article

Pharmacokinetics of continuous once-a-week combination 17β-Estradiol/Low- or high-dose levonorgestrel transdermal delivery systems in postmenopausal women.

Published in:

2014

By:

Karara, Adel H.;
Harrison, Lester I.;
Melikian, Armen P.;
Poola, Nagaraju;
Morrison, Dennis;
Bourg, Dale;
Bourg, Linda;
Zurth, Christian

Publication type:

Journal Article

A phase I open-label study to investigate the potential drug-drug interaction between single-dose dacomitinib and steady-state paroxetine in healthy volunteers.

Published in:

Journal of Clinical Pharmacology, 2014, v. 54, n. 5, p. 555, doi. 10.1002/jcph.243

By:

Ruiz‐Garcia, Ana;
Giri, Nagdeep;
LaBadie, Robert R.;
Ni, Grace;
Boutros, Tanya;
Richie, Nicole;
Kocinsky, Hetal S.;
Checchio, Tina M.;
Bello, Carlo L.

Publication type:

Article

Tigecycline pharmacokinetics, tolerability, safety, and effect on intestinal microflora in healthy Japanese male subjects.

Published in:

Journal of Clinical Pharmacology, 2014, v. 54, n. 5, p. 513, doi. 10.1002/jcph.236

By:

Yamashita, Noriaki;
Matschke, Kyle;
Gandhi, Ashesh;
Korth‐Bradley, Joan

Publication type:

Article

Pharmacokinetic characterization of baclofen in patients with chronic kidney disease: dose adjustment recommendations.

Published in:

Journal of Clinical Pharmacology, 2014, v. 54, n. 5, p. 584, doi. 10.1002/jcph.247

By:

Vlavonou, Raphaël;
Perreault, Marc M.;
Barrière, Olivier;
Shink, Eric;
Tremblay, Pierre‐Olivier;
Larouche, Richard;
Pichette, Vincent;
Tanguay, Mario

Publication type:

Article

Pharmacokinetics of continuous once-a-week combination 17β-Estradiol/Low- or high-dose levonorgestrel transdermal delivery systems in postmenopausal women.

Published in:

Journal of Clinical Pharmacology, 2014, v. 54, n. 5, p. 520, doi. 10.1002/jcph.238

By:

Karara, Adel H.;
Harrison, Lester I.;
Melikian, Armen P.;
Poola, Nagaraju;
Morrison, Dennis;
Bourg, Dale;
Bourg, Linda;
Zurth, Christian

Publication type:

Article

Issue Information.

Published in:: Journal of Clinical Pharmacology, 2014, v. 54, n. 5, p. i, doi. 10.1002/jcph.287
Publication type:: Article

Pharmacokinetics, safety, and efficacy of FOLFIRI plus bevacizumab in Japanese colorectal cancer patients with UGT1A1 gene polymorphisms.

Published in:

Journal of Clinical Pharmacology, 2014, v. 54, n. 5, p. 495, doi. 10.1002/jcph.246

By:

Suenaga, Mitsukuni;
Fuse, Nozomu;
Yamaguchi, Tatsuro;
Yamanaka, Yasuhiro;
Motomura, Shigeki;
Matsumoto, Hiroshi;
Hamamoto, Yasuo;
Mizunuma, Nobuyuki;
Doi, Toshihiko;
Hatake, Kiyohiko;
Iwasaki, Junko;
Ohtsu, Atsushi

Publication type:

Article

Similar Relationship Between the Time Course of Bone Mineral Density Improvement and Vertebral Fracture Risk Reduction With Denosumab Treatment in Postmenopausal Osteoporosis and Prostate Cancer Patients on Androgen Deprivation Therapy.

Published in:

Journal of Clinical Pharmacology, 2014, v. 54, n. 5, p. 503, doi. 10.1002/jcph.228

By:

Pérez Ruixo, Juan Jose;
Zheng, Jenny;
Mandema, Jaap W.

Publication type:

Article

Evaluation of D-ribose pharmacokinetics, dose proportionality, food effect, and pharmacodynamics after oral solution administration in healthy male and female subjects.

Published in:

Journal of Clinical Pharmacology, 2014, v. 54, n. 5, p. 546, doi. 10.1002/jcph.241

By:

Thompson, Jeff;
Neutel, Joel;
Homer, Ken;
Tempero, Ken;
Shah, Ajit;
Khankari, Raj

Publication type:

Article

Pharmacokinetic interaction between etravirine or rilpivirine and telaprevir in healthy volunteers: A randomized, two-way crossover trial.

Published in:

Journal of Clinical Pharmacology, 2014, v. 54, n. 5, p. 563, doi. 10.1002/jcph.245

By:

Kakuda, Thomas N.;
Leopold, Lorant;
Nijs, Steven;
Vandevoorde, Ann;
Crauwels, Herta M.;
Bertelsen, Kirk M.;
Stevens, Marita;
Witek, James;
van Delft, Yvon;
Tomaka, Frank;
Hoetelmans, Richard M.W.

Publication type:

Article

A comprehensive review of the pharmacokinetics of approved therapeutic monoclonal antibodies in Japan: Are Japanese phase I studies still needed?

Published in:

Journal of Clinical Pharmacology, 2014, v. 54, n. 5, p. 483, doi. 10.1002/jcph.231

By:

Chiba, Koji;
Yoshitsugu, Hiroyuki;
Kyosaka, Yuto;
Iida, Satofumi;
Yoneyama, Koichiro;
Tanigawa, Takahiko;
Fukushima, Takashi;
Hiraoka, Masaki

Publication type:

Article

Safety, tolerability, pharmacokinetics, and pharmacodynamics of the novel γ-secretase modulator, E2212, in healthy human subjects.

Published in:

Journal of Clinical Pharmacology, 2014, v. 54, n. 5, p. 528, doi. 10.1002/jcph.249

By:

Yu, Yanke;
Logovinsky, Veronika;
Schuck, Edgar;
Kaplow, June;
Chang, Min‐kun;
Miyagawa, Takehiko;
Wong, Nancy;
Ferry, Jim

Publication type:

Article

Utility of population pharmacokinetic modeling in the assessment of therapeutic protein-drug interactions.

Published in:

Journal of Clinical Pharmacology, 2014, v. 54, n. 5, p. 593, doi. 10.1002/jcph.240

By:

Chow, Andrew T.;
Earp, Justin C.;
Gupta, Manish;
Hanley, William;
Hu, Chuanpu;
Wang, Diane D.;
Zajic, Stefan;
Zhu, Min

Publication type:

Article

Population PKPD of voclosporin in renal allograft patients.

Published in:

Journal of Clinical Pharmacology, 2014, v. 54, n. 5, p. 537, doi. 10.1002/jcph.237

By:

Mayo, P.R.;
Ling, S.Y.;
Huizinga, R.B.;
Freitag, D.G.;
Aspeslet, L.J.;
Foster, R.T.

Publication type:

Article

Expression of six drug transporters in vaginal, cervical, and colorectal tissues: Implications for drug disposition in HIV prevention.

Published in:

Journal of Clinical Pharmacology, 2014, v. 54, n. 5, p. 574, doi. 10.1002/jcph.248

By:

Nicol, Melanie R.;
Fedoriw, Yuri;
Mathews, Michelle;
Prince, Heather M. A.;
Patterson, Kristine B.;
Geller, Elizabeth;
Mollan, Katie;
Mathews, Stephanie;
Kroetz, Deanna L;
Kashuba, Angela D. M.

Publication type:

Article