Works matching DE "HYDROXYCHOLESTEROLS"

Results: 426

Bile acid synthesis, modulation, and dementia: A metabolomic, transcriptomic, and pharmacoepidemiologic study.

Published in:

2021

By:

Varma, Vijay R.;
Wang, Youjin;
An, Yang;
Varma, Sudhir;
Bilgel, Murat;
Doshi, Jimit;
Legido-Quigley, Cristina;
Delgado, João C.;
Oommen, Anup M.;
Roberts, Jackson A.;
Wong, Dean F.;
Davatzikos, Christos;
Resnick, Susan M.;
Troncoso, Juan C.;
Pletnikova, Olga;
O'Brien, Richard;
Hak, Eelko;
Baak, Brenda N.;
Pfeiffer, Ruth;
Baloni, Priyanka

Publication type:

journal article

A CHCHD6–APP axis connects amyloid and mitochondrial pathology in Alzheimer's disease.

Published in:

Acta Neuropathologica, 2022, v. 144, n. 5, p. 911, doi. 10.1007/s00401-022-02499-0

By:

Shang, Yutong;
Sun, Xiaoyan;
Chen, Xiaoqin;
Wang, Quanqiu;
Wang, Evan J.;
Miller, Emiko;
Xu, Rong;
Pieper, Andrew A.;
Qi, Xin

Publication type:

Article

Restoring brain cholesterol turnover improves autophagy and has therapeutic potential in mouse models of spinocerebellar ataxia.

Published in:

Acta Neuropathologica, 2019, v. 138, n. 5, p. 837, doi. 10.1007/s00401-019-02019-7

By:

Nóbrega, Clévio;
Mendonça, Liliana;
Marcelo, Adriana;
Lamazière, Antonin;
Tomé, Sandra;
Despres, Gaetan;
Matos, Carlos A.;
Mechmet, Fatich;
Langui, Dominique;
den Dunnen, Wilfred;
de Almeida, Luis Pereira;
Cartier, Nathalie;
Alves, Sandro

Publication type:

Article

Role of Lipids in Regulation of Neuroglial Interactions.

Published in:

Biochemistry (00062979), 2023, v. 88, n. 3, p. 337, doi. 10.1134/S0006297923030045

By:

Galkina, Olga V.;
Vetrovoy, Oleg V.;
Krasovskaya, Irina E.;
Eschenko, Nataliya D.

Publication type:

Article

Distinct oxysterol requirements for positioning naïve and activated dendritic cells in the spleen.

Published in:

Science Immunology, 2017, v. 2, n. 10, p. 1, doi. 10.1126/sciimmunol.aal5237

By:

Erick Lu;
Dang, Eric V.;
McDonald, Jeffrey G.;
Cyster, Jason G.

Publication type:

Article

Rivaroxaban protects from the oxysterol-induced damage and inflammatory activation of the vascular endothelium.

Published in:

Tissue Barriers, 2021, v. 9, n. 4, p. 1, doi. 10.1080/21688370.2021.1956284

By:

Gorzelak-Pabis, Paulina;
Broncel, Marlena;
Wojdan, Katarzyna;
Gajewski, Adrian;
Chalubinski, Maciej;
Gawrysiak, Mateusz;
Wozniak, Ewelina

Publication type:

Article

Oral administration of repurposed drug targeting Cyp46A1 increases survival times of prion infected mice.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01162-1

By:

Ali, Tahir;
Hannaoui, Samia;
Nemani, Satish;
Tahir, Waqas;
Zemlyankina, Irina;
Cherry, Pearl;
Shim, Su Yeon;
Sim, Valerie;
Schaetzl, Hermann M.;
Gilch, Sabine

Publication type:

Article

Effects of Complete and Partial Loss of the 24S-Hydroxycholesterol-Generating Enzyme Cyp46a1 on Behavior and Hippocampal Transcription in Mouse.

Published in:

Biomolecules (2218-273X), 2024, v. 14, n. 3, p. 254, doi. 10.3390/biom14030254

By:

Shu, Hong-Jin;
Ziolkowski, Luke H.;
Salvatore, Sofia V.;
Benz, Ann M.;
Wozniak, David F.;
Yuede, Carla M.;
Paul, Steven M.;
Zorumski, Charles F.;
Mennerick, Steven

Publication type:

Article

Chronic Aripiprazole and Trazodone Polypharmacy Effects on Systemic and Brain Cholesterol Biosynthesis.

Published in:

Biomolecules (2218-273X), 2023, v. 13, n. 9, p. 1321, doi. 10.3390/biom13091321

By:

Korade, Zeljka;
Anderson, Allison;
Balog, Marta;
Tallman, Keri A.;
Porter, Ned A.;
Mirnics, Karoly

Publication type:

Article

Grafting of Cyclodextrin to Theranostic Nanoparticles Improves Blood-Brain Barrier Model Crossing.

Published in:

Biomolecules (2218-273X), 2023, v. 13, n. 3, p. 573, doi. 10.3390/biom13030573

By:

Puglisi, Antonino;
Bognanni, Noemi;
Vecchio, Graziella;
Bayir, Ece;
van Oostrum, Peter;
Shepherd, Dawn;
Platt, Frances;
Reimhult, Erik

Publication type:

Article

Modelling Hyperglycaemia in an Epithelial Membrane Model: Biophysical Characterisation.

Published in:

Biomolecules (2218-273X), 2022, v. 12, n. 10, p. N.PAG, doi. 10.3390/biom12101534

By:

Reis, Ana;
Teixeira, Joana P. F.;
Silva, Ana M. G.;
Ferreira, Mariana;
Gameiro, Paula;
de Freitas, Victor

Publication type:

Article

Cholesterol: An important actor on the cancer immune scene.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.1057546

By:

Halimi, Hossein;
Farjadian, Shirin

Publication type:

Article

CD4<sup>+</sup>-mediated colitis in mice is independent of the GPR183 and GPR18 pathways.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.1034648

By:

Dicker, Martina;
Yingcong Li;
Giles, Daniel A.;
Verstichel, Greet;
Castelan, Viankail Cedillo;
Ascui-Gac, Gabriel;
Ting-Fang Chou;
Perez-Jeldres, Tamara;
Cheroutre, Hilde;
Kronenberg, Mitchell

Publication type:

Article

Metabolic profile‐based subgroups can identify differences in brain volumes and brain iron deposition.

Published in:

Diabetes, Obesity & Metabolism, 2023, v. 25, n. 1, p. 121, doi. 10.1111/dom.14853

By:

Lumsden, Amanda L.;
Mulugeta, Anwar;
Mäkinen, Ville‐Petteri;
Hyppönen, Elina

Publication type:

Article

Cholesterol Modulates the Interaction between HIV-1 Viral Protein R and Membrane.

Published in:

Membranes, 2021, v. 11, n. 10, p. 784, doi. 10.3390/membranes11100784

By:

Liu, Chun-Hao;
Huang, Shing-Jong;
Yu, Tsyr-Yan

Publication type:

Article

Formation of cholesterol Bilayer Domains Precedes Formation of Cholesterol Crystals in Membranes Made of the Major Phospholipids of Human Eye Lens Fiber Cell Plasma Membranes.

Published in:

Current Eye Research, 2020, v. 45, n. 2, p. 162, doi. 10.1080/02713683.2019.1662058

By:

Mainali, Laxman;
Pasenkiewicz-Gierula, Marta;
Subczynski, Witold K.

Publication type:

Article

Prediagnostic concentrations of circulating bile acids and hepatocellular carcinoma risk: REVEAL‐HBV and HCV studies.

Published in:

International Journal of Cancer, 2020, v. 147, n. 10, p. 2743, doi. 10.1002/ijc.33051

By:

Petrick, Jessica L.;
Florio, Andrea A.;
Koshiol, Jill;
Pfeiffer, Ruth M.;
Yang, Baiyu;
Yu, Kelly;
Chen, Chien‐Jen;
Yang, Hwai‐I;
Lee, Mei‐Hsuan;
McGlynn, Katherine A.

Publication type:

Article

Cholesterol sulfate alleviates ulcerative colitis by promoting cholesterol biosynthesis in colonic epithelial cells.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32158-7

By:

Xu, Dongke;
Ma, Ruijun;
Ju, Yi;
Song, Xiaowei;
Niu, Baolin;
Hong, Wenting;
Wang, Rong;
Yang, Qin;
Zhao, Zhi;
Zhang, Yuchen;
Zheng, Yufan;
Bai, Qianming;
Lv, Mingfang;
Sun, Ning;
Li, Xiaobo

Publication type:

Article

Hypercholesterolemia in the Malaysian Cohort Participants: Genetic and Non-Genetic Risk Factors.

Published in:

Genes, 2023, v. 14, n. 3, p. 721, doi. 10.3390/genes14030721

By:

Abdul Murad, Nor Azian;
Mohammad Noor, Yusuf;
Mohd. Rani, Zam Zureena;
Sulaiman, Siti Aishah;
Chow, Yock Ping;
Abdullah, Noraidatulakma;
Ahmad, Norfazilah;
Ismail, Norliza;
Abdul Jalal, Nazihah;
Kamaruddin, Mohd. Arman;
Saperi, Amalia Afzan;
Jamal, Rahman

Publication type:

Article

Influence of ursodeoxycholic acid on blood glucose, insulin and GLP-1 in rats with liver fibrosis induced by bile duct ligation.

Published in:

Diabetology & Metabolic Syndrome, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13098-023-00989-z

By:

Bai, Xiu-Ping;
Du, Wen-Jin;
Xing, Hua-Bing;
Yang, Guo-Hua;
Bai, Rui

Publication type:

Article

A Crosstalk Between Brain Cholesterol Oxidation and Glucose Metabolism in Alzheimer's Disease.

Published in:

Frontiers in Neuroscience, 2019, p. N.PAG, doi. 10.3389/fnins.2019.00556

By:

Gamba, Paola;
Staurenghi, Erica;
Testa, Gabriella;
Giannelli, Serena;
Sottero, Barbara;
Leonarduzzi, Gabriella

Publication type:

Article

A Proinflammatory Stimulus Disrupts Hippocampal Plasticity and Learning via Microglial Activation and 25-Hydroxycholesterol.

Published in:

Journal of Neuroscience, 2021, v. 41, n. 49, p. 10054, doi. 10.1523/JNEUROSCI.1502-21.2021

By:

Yukitoshi Izumi;
Cashikar, Anil G.;
Krishnan, Kathiresan;
Paul, Steven M.;
Covey, Douglas F.;
Mennerick, Steven J.;
Zorumski, Charles F.

Publication type:

Article

Effect of Low-Fat Diets Enriched with Fruit Purees on the Biochemical Markers of Metabolic Syndrome Analogy Induced-Rats.

Published in:

International Journal of Morphology, 2020, v. 38, n. 1, p. 61, doi. 10.4067/s0717-95022020000100061

By:

Morales-Ávila, Úrsula Mireya;
Yahia, Elhadi M.;
Montalvo-González, Rubén;
Becerra-Verdín, Eduardo Mendeleev;
Montalvo-González, Efigenia

Publication type:

Article

A Novel Method for the Determination of Squalene, Cholesterol and Their Oxidation Products in Food of Animal Origin by GC-TOF/MS.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 5, p. 2807, doi. 10.3390/ijms25052807

By:

Czerwonka, Małgorzata;
Białek, Agnieszka;
Bobrowska-Korczak, Barbara

Publication type:

Article

Side-Chain Immune Oxysterols Induce Neuroinflammation by Activating Microglia.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 20, p. 15288, doi. 10.3390/ijms242015288

By:

Son, Yonghae;
Yeo, In-Jun;
Hong, Jin-Tae;
Eo, Seong-Kug;
Lee, Dongjun;
Kim, Koanhoi

Publication type:

Article

Aerobic Exercise Facilitates the Nuclear Translocation of SREBP2 by Activating AKT/SEC24D to Contribute Cholesterol Homeostasis for Improving Cognition in APP/PS1 Mice.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 16, p. 12847, doi. 10.3390/ijms241612847

By:

Hu, Zelin;
Yuan, Yangqi;
Tong, Zhen;
Liao, Meiqing;
Yuan, Shunling;
Wu, Weijia;
Tang, Yingzhe;
Wang, Yirong;
Tang, Changfa;
Liu, Wenfeng

Publication type:

Article

Parkinson's Disease and the Heart: Studying Cardiac Metabolism in the 6-Hydroxydopamine Model.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 15, p. 12202, doi. 10.3390/ijms241512202

By:

Silva da Fonsêca, Victor;
Goncalves, Valeria de Cassia;
Augusto Izidoro, Mario;
Guimarães de Almeida, Antônio-Carlos;
Luiz Affonso Fonseca, Fernando;
Alexandre Scorza, Fulvio;
Finsterer, Josef;
Scorza, Carla Alessandra

Publication type:

Article

Low-Density Lipoprotein Receptor (LDLR) Is Involved in Internalization of Lentiviral Particles Pseudotyped with SARS-CoV-2 Spike Protein in Ocular Cells.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 14, p. 11860, doi. 10.3390/ijms241411860

By:

Uppal, Sheetal;
Postnikova, Olga;
Villasmil, Rafael;
Rogozin, Igor B.;
Bocharov, Alexander V.;
Eggerman, Thomas L.;
Poliakov, Eugenia;
Redmond, T. Michael

Publication type:

Article

Sigma-2 Receptor Ligand Binding Modulates Association between TSPO and TMEM97.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 7, p. 6381, doi. 10.3390/ijms24076381

By:

Thejer, Bashar M.;
Infantino, Vittoria;
Santarsiero, Anna;
Pappalardo, Ilaria;
Abatematteo, Francesca S.;
Teakel, Sarah;
Van Oosterum, Ashleigh;
Mach, Robert H.;
Denora, Nunzio;
Lee, Byung Chul;
Resta, Nicoletta;
Bagnulo, Rosanna;
Niso, Mauro;
Contino, Marialessandra;
Montsch, Bianca;
Heffeter, Petra;
Abate, Carmen;
Cahill, Michael A.

Publication type:

Article

TNFα Activates the Liver X Receptor Signaling Pathway and Promotes Cholesterol Efflux from Human Brain Pericytes Independently of ABCA1.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 6, p. 5992, doi. 10.3390/ijms24065992

By:

Dib, Shiraz;
Loiola, Rodrigo Azevedo;
Sevin, Emmanuel;
Saint-Pol, Julien;
Shimizu, Fumitaka;
Kanda, Takashi;
Pahnke, Jens;
Gosselet, Fabien

Publication type:

Article

Elucidation of OSW-1-Induced Stress Responses in Neuro2a Cells.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 6, p. 5787, doi. 10.3390/ijms24065787

By:

Oh-hashi, Kentaro;
Nakamura, Hibiki;
Ogawa, Hirotaka;
Hirata, Yoko;
Sakurai, Kaori

Publication type:

Article

The Impacts of Cholesterol, Oxysterols, and Cholesterol Lowering Dietary Compounds on the Immune System.

Published in:

2022

By:

Yanagisawa, Rintaro;
He, Chaoqi;
Asai, Akira;
Hellwig, Michael;
Henle, Thomas;
Toda, Masako

Publication type:

Literature Review

Diverse Sphingolipid Species Harbor Different Effects on Ire1 Clustering.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 20, p. 12130, doi. 10.3390/ijms232012130

By:

Bieniawski, Mark A.;
Stevens, Kofi L. P.;
Witham, Christopher M.;
Steuart, Robert F. L.;
Bankaitis, Vytas A.;
Mousley, Carl J.

Publication type:

Article

Linking Late Endosomal Cholesterol with Cancer Progression and Anticancer Drug Resistance.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 13, p. 7206, doi. 10.3390/ijms23137206

By:

Nguyen, Mai K. L.;
Jose, Jaimy;
Wahba, Mohamed;
Bernaus-Esqué, Marc;
Hoy, Andrew J.;
Enrich, Carlos;
Rentero, Carles;
Grewal, Thomas

Publication type:

Article

Brain Cholesterol Biosynthetic Pathway Is Altered in a Preclinical Model of Fragile X Syndrome.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 6, p. 3408, doi. 10.3390/ijms23063408

By:

Parente, Martina;
Tonini, Claudia;
Buzzelli, Valeria;
Carbone, Emilia;
Trezza, Viviana;
Pallottini, Valentina

Publication type:

Article

Secretory NPC2 Protein-Mediated Free Cholesterol Levels Were Correlated with the Sorafenib Response in Hepatocellular Carcinoma.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 16, p. 8567, doi. 10.3390/ijms22168567

By:

Suk, Fat-Moon;
Wang, Yuan-Hsi;
Chiu, Wan-Chun;
Liu, Chiao-Fan;
Wu, Chien-Ying;
Chen, Tzu-Lang;
Liao, Yi-Jen

Publication type:

Article

25-Hydroxycholesterol Effect on Membrane Structure and Mechanical Properties.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 5, p. 2574, doi. 10.3390/ijms22052574

By:

Domingues, Marco M.;
Gomes, Bárbara;
Hollmann, Axel;
Santos, Nuno C.;
Nicholls, Ian A.

Publication type:

Article

Influence of Antiplatelet Agents on the Lipid Composition of Platelet Plasma Membrane: A Lipidomics Approach with Ticagrelor and Its Active Metabolite.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 3, p. 1432, doi. 10.3390/ijms22031432

By:

Lagoutte-Renosi, Jennifer;
Allemand, Florentin;
Ramseyer, Christophe;
Rabani, Vahideh;
Davani, Siamak;
Medvedev, Ilya Nikolaevich

Publication type:

Article

Transmembrane Polar Relay Drives the Allosteric Regulation for ABCG5/G8 Sterol Transporter.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 22, p. 8747, doi. 10.3390/ijms21228747

By:

Xavier, Bala M.;
Zein, Aiman A.;
Venes, Angelica;
Wang, Junmei;
Lee, Jyh-Yeuan

Publication type:

Article

Orphan Nuclear Receptor RORα Regulates Enzymatic Metabolism of Cerebral 24S-Hydroxycholesterol through CYP39A1 Intronic Response Element Activation.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 9, p. 3309, doi. 10.3390/ijms21093309

By:

Matsuoka, Hiroshi;
Katayama, Miyu;
Ohishi, Ami;
Miya, Kaoruko;
Tokunaga, Riki;
Kobayashi, Sou;
Nishimoto, Yuya;
Hirooka, Kazutake;
Shima, Akiho;
Michihara, Akihiro

Publication type:

Article

The Protective Effect of Dabigatran and Rivaroxaban on DNA Oxidative Changes in a Model of Vascular Endothelial Damage with Oxidized Cholesterol.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 6, p. 1953, doi. 10.3390/ijms21061953

By:

Woźniak, Ewelina;
Broncel, Marlena;
Bukowska, Bożena;
Gorzelak-Pabiś, Paulina

Publication type:

Article

Cholesterol, Oxysterols and LXRs in Breast Cancer Pathophysiology.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 4, p. 1356, doi. 10.3390/ijms21041356

By:

Nazih, Hassan;
Bard, Jean Marie

Publication type:

Article

Liver X Receptors and Male (In)fertility.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 21, p. 5379, doi. 10.3390/ijms20215379

By:

Jarvis, Sheba;
Williamson, Catherine;
Bevan, Charlotte L

Publication type:

Article

Regulation of Brain Cholesterol: What Role Do Liver X Receptors Play in Neurodegenerative Diseases?

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 16, p. 3858, doi. 10.3390/ijms20163858

By:

Mouzat, Kevin;
Chudinova, Aleksandra;
Polge, Anne;
Kantar, Jovana;
Camu, William;
Raoul, Cédric;
Lumbroso, Serge

Publication type:

Article

Cholesterol Acceptors Regulate the Lipidome of Macrophage Foam Cells.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 15, p. 3784, doi. 10.3390/ijms20153784

By:

Paul, Antoni;
Lydic, Todd A.;
Hogan, Ryan;
Goo, Young-Hwa

Publication type:

Article

Familial Hypercholesterolemia: The Most Frequent Cholesterol Metabolism Disorder Caused Disease.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 11, p. 3426, doi. 10.3390/ijms19113426

By:

Benito-Vicente, Asier;
Uribe, Kepa B.;
Jebari, Shifa;
Galicia-Garcia, Unai;
Ostolaza, Helena;
Martin, Cesar

Publication type:

Article

27-Hydroxycholesterol increases α-synuclein protein levels through proteasomal inhibition in human dopaminergic neurons.

Published in:

2018

By:

Schommer, Jared;
Marwarha, Gurdeep;
Schommer, Trevor;
Flick, Travis;
Lund, Jonah;
Ghribi, Othman

Publication type:

journal article

Deregulation of hepatic lipid metabolism associated with insulin resistance in rats subjected to chronic monocrotophos exposure.

Published in:

Journal of Biochemical & Molecular Toxicology, 2020, v. 34, n. 8, p. 1, doi. 10.1002/jbt.22506

By:

Nagaraju, Raju;
Joshi, Apurva K. R.;
Vamadeva, Sowmya G.;
Rajini, Padmanabhan S.

Publication type:

Article

25-Hydroxycholesterols in innate and adaptive immunity.

Published in:

Nature Reviews Immunology, 2014, v. 14, n. 11, p. 731, doi. 10.1038/nri3755

By:

Cyster, Jason G.;
Dang, Eric V.;
Reboldi, Andrea;
Yi, Tangsheng

Publication type:

Article

Effect of Coffee on the Bioavailability of Sterols.

Published in:

Foods, 2022, v. 11, n. 19, p. 2935, doi. 10.3390/foods11192935

By:

Pires, Cristiana L.;
Silva, Inês M. V.;
Coimbra, Manuel A.;
Moreno, Maria João;
Coreta-Gomes, Filipe

Publication type:

Article