Title: Bisphenol-A can bind to human glucocorticoid receptor as an agonist: an in silico study.
Authors: Prasanth, G. K.; Divya, L. M.; Sadasivan, C.
Abstract: The article presents a study which examines the ability of Bisphenol-A (BPA) to combine with human glucocorticoid receptor (GR) and its binding interaction through molecular docking and modeling techniques. The study uses the Insight II and Discovery Studio 2.0 software from Accelrys Software Inc. to simulate amd analyze, BPA in which reconstruction of missing amino acids was performed. Results of the study reveal the ability of BPA to bind with GR in an agonist form.
Subjects: BISPHENOL A; GLUCOCORTICOID receptors; AMINO acids; BINDING sites; ACCELRYS Software Inc.
Publication: Journal of Applied Toxicology, 2010, Vol 30, Issue 8, p769
ISSN: 0260-437X
Publication type: Academic Journal
DOI: 10.1002/jat.1570

Bisphenol-A can bind to human glucocorticoid receptor as an agonist: an in silico study.

Prasanth, G. K.; Divya, L. M.; Sadasivan, C.