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Gene of the month: C-KIT.
- Published in:
- Indian Journal of Cancer, 2024, v. 61, n. 3, p. 421, doi. 10.4103/ijc.ijc_1350_21
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- Publication type:
- Article
Erlotinib Improves the Response of Glioblastoma Cells Resistant to Photodynamic Therapy.
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- Brain Sciences (2076-3425), 2024, v. 14, n. 12, p. 1192, doi. 10.3390/brainsci14121192
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- Publication type:
- Article
O -GlcNAcylation of Focal Adhesion Kinase Regulates Cell Adhesion, Migration, and Proliferation via the FAK/AKT Pathway.
- Published in:
- Biomolecules (2218-273X), 2024, v. 14, n. 12, p. 1577, doi. 10.3390/biom14121577
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- Publication type:
- Article
Serum EphA2 as a Promising Biomarker for the Early Detection and Diagnosis of Colorectal Cancer.
- Published in:
- Biomolecules (2218-273X), 2024, v. 14, n. 12, p. 1504, doi. 10.3390/biom14121504
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- Publication type:
- Article
DDR1 in pancreatic adenocarcinoma: unraveling the mechanisms of immune exclusion.
- Published in:
- Scandinavian Journal of Gastroenterology, 2025, v. 60, n. 1, p. 81, doi. 10.1080/00365521.2024.2443505
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- Publication type:
- Article
Virology: Keeping HSV-1 dormant.
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- Nature Reviews Microbiology, 2010, v. 8, n. 12, p. 838, doi. 10.1038/nrmicro2480
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- Publication type:
- Article
Bacterial virulence: The integrin connection.
- Published in:
- Nature Reviews Microbiology, 2007, v. 5, n. 12, p. 908, doi. 10.1038/nrmicro1805
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- Publication type:
- Article
Bacterial pathogenesis: Two steps further forward for Listeria.
- Published in:
- Nature Reviews Microbiology, 2007, v. 5, n. 9, p. 657, doi. 10.1038/nrmicro1732
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- Publication type:
- Article
Virology: Henipavirus receptor identified.
- Published in:
- Nature Reviews Microbiology, 2005, v. 3, n. 9, p. 666, doi. 10.1038/nrmicro1257
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- Publication type:
- Article
Imatinib Mesylate Pharmacokinetics Before and After Sleeve Gastrectomy in a Morbidly Obese Patient with Chronic Myeloid Leukemia.
- Published in:
- Pharmacotherapy, 2009, v. 29, n. 9, p. 1152, doi. 10.1592/phco.29.9.1152
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- Publication type:
- Article
Lapatinib and Ixabepilone for the Treatment of Metastatic Breast Cancer.
- Published in:
- Pharmacotherapy, 2008, v. 28, n. 10, p. 1255, doi. 10.1592/phco.28.10.1255
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- Publication type:
- Article
TIRF high-content assay development for the evaluation of drug efficacy of chemotherapeutic agents against EGFR-/HER2-positive breast cancer cell lines.
- Published in:
- Analytical & Bioanalytical Chemistry, 2016, v. 408, n. 12, p. 3233, doi. 10.1007/s00216-016-9387-1
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- Publication type:
- Article
Initial diagnosis of chronic myelogenous leukemia based on quantification of M- BCR status using droplet digital PCR.
- Published in:
- Analytical & Bioanalytical Chemistry, 2016, v. 408, n. 4, p. 1079, doi. 10.1007/s00216-015-9204-2
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- Publication type:
- Article
Conjugation-free, visual, and quantitative evaluation of inhibitors on protein tyrosine kinases and phosphatases with a luminescent Tb(III) complex.
- Published in:
- Analytical & Bioanalytical Chemistry, 2014, v. 406, n. 12, p. 2957, doi. 10.1007/s00216-014-7707-x
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- Publication type:
- Article
Development and validation of a UPLC-MS/MS assay for the quantification of simotinib in human plasma.
- Published in:
- Analytical & Bioanalytical Chemistry, 2014, v. 406, n. 6, p. 1799, doi. 10.1007/s00216-013-7570-1
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- Publication type:
- Article
Multiplexed tyrosine kinase activity detection in cancer cells using a hydrogel immobilized substrate.
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- Analytical & Bioanalytical Chemistry, 2013, v. 405, n. 16, p. 5489, doi. 10.1007/s00216-013-6963-5
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- Publication type:
- Article
An automated method for the measurement of a range of tyrosine kinase inhibitors in human plasma or serum using turbulent flow liquid chromatography-tandem mass spectrometry.
- Published in:
- Analytical & Bioanalytical Chemistry, 2012, v. 403, n. 6, p. 1685, doi. 10.1007/s00216-012-5970-2
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- Publication type:
- Article
A new method of high-speed cellular protein separation and insight into subcellular compartmentalization of proteins.
- Published in:
- Analytical & Bioanalytical Chemistry, 2011, v. 400, n. 3, p. 767, doi. 10.1007/s00216-011-4810-0
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- Publication type:
- Article
Modulation of Src Kinase Activity by Selective Substrate Recognition with Pseudopeptidic Cages.
- Published in:
- Chemistry - A European Journal, 2021, v. 27, n. 37, p. 9542, doi. 10.1002/chem.202100990
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- Publication type:
- Article
Glycan Modulation of Insulin‐like Growth Factor‐1 Receptor.
- Published in:
- Angewandte Chemie, 2022, v. 134, n. 49, p. 1, doi. 10.1002/ange.202211320
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- Publication type:
- Article
Synergy and Antagonism between Allosteric and Active‐Site Inhibitors of Abl Tyrosine Kinase.
- Published in:
- Angewandte Chemie, 2021, v. 133, n. 37, p. 20358, doi. 10.1002/ange.202105351
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- Publication type:
- Article
Design of Turn‐On Near‐Infrared Fluorescent Probes for Highly Sensitive and Selective Monitoring of Biopolymers.
- Published in:
- Angewandte Chemie, 2020, v. 132, n. 22, p. 8518, doi. 10.1002/ange.202000108
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- Publication type:
- Article
Antisense oligonucleotides as a targeted therapeutic approach in model of acute myeloid leukemia.
- Published in:
- Molecular Biology Reports, 2024, v. 52, n. 1, p. 1, doi. 10.1007/s11033-024-10172-w
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- Publication type:
- Article
Water molecules in protein-ligand interfaces. Evaluation of software tools and SAR comparison.
- Published in:
- Journal of Computer-Aided Molecular Design, 2019, v. 33, n. 3, p. 307, doi. 10.1007/s10822-019-00187-y
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- Publication type:
- Article
Structure-guided optimization of small molecule c-Abl activators.
- Published in:
- Journal of Computer-Aided Molecular Design, 2014, v. 28, n. 2, p. 75, doi. 10.1007/s10822-014-9731-5
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- Publication type:
- Article
Computational study of the effects of protein tyrosine nitrations on the catalytic activity of human thymidylate synthase.
- Published in:
- Journal of Computer-Aided Molecular Design, 2013, v. 27, n. 1, p. 45, doi. 10.1007/s10822-012-9624-4
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- Publication type:
- Article
Extraction and validation of substructure profiles for enriching compound libraries.
- Published in:
- Journal of Computer-Aided Molecular Design, 2012, v. 26, n. 10, p. 1127, doi. 10.1007/s10822-012-9604-8
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- Publication type:
- Article
Triple hydrogen bonding in a circular arrangement: ab initio, DFT and first-principles MD studies of tris-hydroxyaryl enamines.
- Published in:
- Journal of Computer-Aided Molecular Design, 2012, v. 26, n. 9, p. 1045, doi. 10.1007/s10822-012-9597-3
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- Publication type:
- Article
Identification of common inhibitors of wild-type and T315I mutant of BCR-ABL through the parallel structure-based virtual screening.
- Published in:
- Journal of Computer-Aided Molecular Design, 2012, v. 26, n. 8, p. 983, doi. 10.1007/s10822-012-9593-7
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- Publication type:
- Article
Structure-based design of oxygen-linked macrocyclic kinase inhibitors: discovery of SB1518 and SB1578, potent inhibitors of Janus kinase 2 (JAK2) and Fms-like tyrosine kinase-3 (FLT3).
- Published in:
- Journal of Computer-Aided Molecular Design, 2012, v. 26, n. 4, p. 437, doi. 10.1007/s10822-012-9572-z
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- Publication type:
- Article
Can free energy calculations be fast and accurate at the same time? Binding of low-affinity, non-peptide inhibitors to the SH2 domain of the src protein.
- Published in:
- Journal of Computer-Aided Molecular Design, 2005, v. 19, n. 11, p. 765, doi. 10.1007/s10822-005-9021-3
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- Publication type:
- Article
3D-QSAR and docking studies on 4-anilinoquinazoline and 4-anilinoquinoline epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors.
- Published in:
- Journal of Computer-Aided Molecular Design, 2003, v. 17, n. 8, p. 475, doi. 10.1023/B:JCAM.0000004622.13865.4f
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- Publication type:
- Article
Synthesis and preclinical evaluation of a selective MET kinase positron emission tomography tracer.
- Published in:
- Journal of Labelled Compounds & Radiopharmaceuticals, 2023, v. 66, n. 14, p. 452, doi. 10.1002/jlcr.4066
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- Publication type:
- Article
Radiosynthesis of a Bruton's tyrosine kinase inhibitor, [<sup>11</sup>C]Tolebrutinib, via palladium‐NiXantphos‐mediated carbonylation.
- Published in:
- Journal of Labelled Compounds & Radiopharmaceuticals, 2020, v. 63, n. 11, p. 482, doi. 10.1002/jlcr.3872
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- Publication type:
- Article
Synthesis of imatinib, a tyrosine kinase inhibitor, labeled with carbon‐14.
- Published in:
- Journal of Labelled Compounds & Radiopharmaceuticals, 2020, v. 63, n. 4, p. 174, doi. 10.1002/jlcr.3830
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- Publication type:
- Article
Identifying nonsmall‐cell lung tumours bearing the T790M EGFR TKI resistance mutation using PET imaging.
- Published in:
- Journal of Labelled Compounds & Radiopharmaceuticals, 2019, v. 62, n. 9, p. 596, doi. 10.1002/jlcr.3771
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- Publication type:
- Article
A HYBRID ENERGY‐ AND AI‐BASED SCREENING FOR NOVEL INHIBITORS OF LCK FOR THE TREATMENT OF T‐CELL LYMPHOBLASTIC LYMPHOMA.
- Published in:
- Hematological Oncology, 2023, v. 41, p. 803, doi. 10.1002/hon.3165_652
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- Publication type:
- Article
BCR/ABL1ΔE7‐8‐9 isoform contributes to tyrosine kinase inhibitor resistance in chronic myeloid leukemia.
- Published in:
- Hematological Oncology, 2022, v. 40, n. 5, p. 1067, doi. 10.1002/hon.3040
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- Publication type:
- Article
Combination of KIT and FLT3‐ITD mutation status with minimal residual disease levels guides treatment strategy for adult patients with inv(16) acute myeloid leukemia in first complete remission.
- Published in:
- Hematological Oncology, 2022, v. 40, n. 4, p. 724, doi. 10.1002/hon.3015
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- Publication type:
- Article
Management of patients with acute myeloid leukemia undergoing therapy with midostaurin: a focus on antifungal prophylaxis.
- Published in:
- Hematological Oncology, 2021, v. 39, n. 1, p. 20, doi. 10.1002/hon.2788
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- Publication type:
- Article
A phase 1 study to evaluate the feasibility and efficacy of the addition of ropeginterferon alpha‐2b to imatinib treatment in patients with chronic phase chronic myeloid leukemia (CML) not achieving a deep molecular response (molecular remission 4.5)—AGMT_CML 1
- Published in:
- Hematological Oncology, 2020, v. 38, n. 5, p. 792, doi. 10.1002/hon.2786
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- Publication type:
- Article
The landscape of BCR-ABL mutations in patients with Philadelphia chromosome-positive leukaemias in the era of second-generation tyrosine kinase inhibitors.
- Published in:
- 2020
- By:
- Publication type:
- journal article
Final analysis of a phase 1/2b study of ibrutinib combined with carfilzomib/dexamethasone in patients with relapsed/refractory multiple myeloma.
- Published in:
- 2020
- By:
- Publication type:
- journal article
Ibrutinib in the treatment of chronic lymphocytic leukemia: 5 years on.
- Published in:
- 2020
- By:
- Publication type:
- journal article
Smoking influences the outcomes of patients receiving tyrosine kinase inhibitors for chronic myeloid leukemia in the chronic phase: A retrospective analysis.
- Published in:
- 2019
- By:
- Publication type:
- clinical trial
UPDATED SAFETY AND EFFICACY DATA IN THE PHASE 1 TRIAL OF PATIENTS WITH MANTLE CELL LYMPHOMA (MCL) TREATED WITH BRUTON TYROSINE KINASE (BTK) INHIBITOR ZANUBRUTINIB (BGB‐3111).
- Published in:
- Hematological Oncology, 2019, v. 37, p. 245, doi. 10.1002/hon.55_2630
- By:
- Publication type:
- Article
A PHASE IIA STUDY EVALUATING THE SAFETY AND TOLERABILITY OF UMBRALISIB AND IBRUTINIB IN PATIENTS WITH RELAPSED OR REFRACTORY DIFFUSE LARGE B‐CELL LYMPHOMA.
- Published in:
- Hematological Oncology, 2019, v. 37, p. 519, doi. 10.1002/hon.204_2631
- By:
- Publication type:
- Article
UPDATED SAFETY AND EFFICACY DATA IN THE PHASE 1 TRIAL OF PATIENTS WITH MANTLE CELL LYMPHOMA (MCL) TREATED WITH BRUTON TYROSINE KINASE (BTK) INHIBITOR ZANUBRUTINIB (BGB‐3111).
- Published in:
- Hematological Oncology, 2019, v. 37, p. 245, doi. 10.1002/hon.55_2630
- By:
- Publication type:
- Article
A PHASE IIA STUDY EVALUATING THE SAFETY AND TOLERABILITY OF UMBRALISIB AND IBRUTINIB IN PATIENTS WITH RELAPSED OR REFRACTORY DIFFUSE LARGE B‐CELL LYMPHOMA.
- Published in:
- Hematological Oncology, 2019, v. 37, p. 519, doi. 10.1002/hon.204_2631
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- Publication type:
- Article
The effects of STI571 on antigen presentation of dendritic cells generated from patients with chronic myelogenous leukemia.
- Published in:
- Hematological Oncology, 2003, v. 21, n. 2, p. 67, doi. 10.1002/hon.705
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- Publication type:
- Article