Results
Title

Transition‐Metal‐Free Cascade Cyclization/Dearomatization Reaction to Access Selenylated Spirocyclohexadienones.

Authors

Liu, Yi; Liu, Miao‐Chang; Zhou, Yun‐Bing; Wu, Hua‐Yue

Abstract

A transition‐metal‐free method is disclosed for the construction of selenylated spirocyclohexadienones via cascade cyclization/dearomatization reaction of aryl phenol‐tethered alkynes with diselenides. The high efficiency of this protocol was demonstrated by room temperature, simple reaction conditions, and the ability to enable a gram‐scale synthesis. The experiment results implied that the dearomatization process proceeded in a radical way.

Subjects

RING formation (Chemistry); RADICALS (Chemistry); ALKYNES; TEMPERATURE

Publication

European Journal of Organic Chemistry, 2023, Vol 26, Issue 47, p1

ISSN

1434-193X

Publication type

Academic Journal

DOI

10.1002/ejoc.202301072