Works matching DE "EDARAVONE"

Results: 139

An Exploratory Trial of EPI-589 in Amyotrophic Lateral Sclerosis (EPIC-ALS): Protocol for a Multicenter, Open-Labeled, 24-Week, Single-Group Study.

Published in:

JMIR Research Protocols, 2023, v. 12, n. 1, p. 819, doi. 10.2196/42032

By:

Shotaro Haji;
Koji Fujita;
Ryosuke Oki;
Yusuke Osaki;
Ryosuke Miyamoto;
Hiroyuki Morino;
Seiichi Nagano;
Naoki Atsuta;
Yuki Kanazawa;
Yuki Matsumoto;
Atsuko Arisawa;
Hisashi Kawai;
Yasutaka Sato;
Satoshi Sakaguchi;
Kenta Yagi;
Tatsuto Hamatani;
Tatsuo Kagimura;
Hiroaki Yanagawa;
Hideki Mochizuki;
Manabu Doyu

Publication type:

Article

Edaravone alleviates lung damage in mice with hypoxic pulmonary hypertension by increasing nitric oxide synthase 3 expression.

Published in:

Korean Journal of Physiology & Pharmacology, 2023, v. 27, n. 3, p. 209, doi. 10.4196/kjpp.2023.27.3.209

By:

Wan Zheng;
Tianfa Li;
Junping Wei;
Yani Yan;
Shanshan Yang

Publication type:

Article

Effect of edaravone in diabetes mellitus-induced nephropathy in rats.

Published in:

Korean Journal of Physiology & Pharmacology, 2016, v. 20, n. 4, p. 333, doi. 10.4196/kjpp.2016.20.4.333

By:

Varatharajan, Rajavel;
Li Xin Lim;
Tan, Kelly;
Chai Sze Tay;
Yi Leng Teoh;
Akhtar, Shaikh Sohrab;
Rupeshkumar, Mani;
Ivy Chung;
Abdullah, Nor Azizan;
Banik, Urmila;
Dhanaraj, Sokkalingam A.;
Balakumar, Pitchai

Publication type:

Article

Effects of edaravone on testicular torsion–detorsion injury in rats.

Published in:

Andrology, 2024, v. 12, n. 8, p. 1918, doi. 10.1111/andr.13628

By:

Şahin, Yaşar;
Üstüner, Evren;
Tutun, Hidayet;
Yildirim, Ebru;
Eroğlu, Oğuz;
Kurtdede, Efe;
Ozkabadayi, Yasin;
Güncüm, Enes;
Kutluca, Kürşat;
Bilge, Ahmet Bilgehan

Publication type:

Article

Evidence for generalizability of edaravone efficacy using a novel machine learning risk-based subgroup analysis tool.

Published in:

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2022, v. 23, n. 1/2, p. 49, doi. 10.1080/21678421.2021.1927102

By:

Brooks, Benjamin Rix;
Pioro, Erik P.;
Beaulieu, Danielle;
Taylor, Albert A.;
Schactman, Mark;
Keymer, Mike;
Agnese, Wendy;
Perdrizet, Johnna;
Apple, Stephen;
Ennist, David L.

Publication type:

Article

Effects of decompressive craniectomy combined with edaravone on postoperative neurological functions and hemodynamics of patients with severe traumatic brain injury.

Published in:

Neurosciences, 2024, v. 29, n. 1, p. 25, doi. 10.17712/nsj.2024.1.20230057

By:

Xinjing Yang

Publication type:

Article

Intravenous Edaravone plus Therapeutic Hypothermia Offers Limited Neuroprotection in the Hypoxic-Ischaemic Newborn Piglet.

Published in:

Neonatology (16617800), 2020, v. 117, n. 6, p. 713, doi. 10.1159/000511085

By:

Yamato, Satoshi Hamano;
Nakamura, Shinji;
Htun, Yinmon;
Nakamura, Makoto;
Jinnai, Wataru;
Nakao, Yasuhiro;
Mitsuie, Tsutomu;
Koyano, Kosuke;
Wakabayashi, Takayuki;
Morimoto, Aya Hashimoto;
Sugino, Masashiro;
Iwase, Takashi;
Kondo, Sonoko Ijichi;
Yasuda, Saneyuki;
Ueno, Masaki;
Miki, Takanori;
Kusaka, Takashi

Publication type:

Article

Protective Impact of Edaravone Against ZnO NPs-induced Oxidative Stress in the Human Neuroblastoma SH-SY5Y Cell Line.

Published in:

Cellular & Molecular Neurobiology, 2022, v. 42, n. 4, p. 1189, doi. 10.1007/s10571-020-01011-0

By:

Singh, Sanjiv;
Gautam, Upendr;
Manvi, F. V.

Publication type:

Article

Effects of edaravone dexborneol on functional outcome and inflammatory response in patients with acute ischemic stroke.

Published in:

BMC Neurology, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12883-024-03712-1

By:

Chen, Wenxia;
Zhang, Hanqing;
Li, Zhenzhen;
Deng, Qiwen;
Wang, Meng;
Chen, Yingbin;
Zhang, Yuan

Publication type:

Article

The design and synthesis of benzylpiperazine-based edaravone derivatives and their neuroprotective activities.

Published in:

Journal of Chemical Research, 2022, v. 46, n. 6, p. 1, doi. 10.1177/17475198221116827

By:

Gao, Mengjie;
Ma, Shuangyan;
Xu, Tong;
Jiang, Nan;
Xu, Yi;
Zhong, Yan;
Wu, Bin

Publication type:

Article

NU-9 improves health of hSOD1<sup>G93A</sup> mouse upper motor neurons in vitro, especially in combination with riluzole or edaravone.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-09332-4

By:

Genç, Barış;
Gautam, Mukesh;
Helmold, Benjamin R.;
Koçak, Nuran;
Günay, Aksu;
Goshu, Gashaw M.;
Silverman, Richard B.;
Hande Ozdinler, P.

Publication type:

Article

Edaravone Administered Orally and Via Nasogastric Tube in Healthy Adults: A Comparative Bioavailability Phase 1 Study.

Published in:

Clinical Pharmacology in Drug Development, 2023, v. 12, n. 1, p. 77, doi. 10.1002/cpdd.1175

By:

Shimizu, Hidetoshi;
Nishimura, Yukiko;
Shiide, Youichi;
Ueda, Masaki;
Yokota, Shoko;
Kato, Yuichiro;
Hirai, Manabu

Publication type:

Article

Bioequivalence Study of Oral Suspension and Intravenous Formulation of Edaravone in Healthy Adult Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 10, p. 1188, doi. 10.1002/cpdd.952

By:

Shimizu, Hidetoshi;
Nishimura, Yukiko;
Shiide, Youichi;
Yoshida, Kaori;
Hirai, Manabu;
Matsuda, Munetomo;
Nakamaru, Yoshinobu;
Kato, Yuichiro;
Kondo, Kazuoki

Publication type:

Article

Evaluation of Pharmacokinetics, Safety, and Drug‐Drug Interactions of an Oral Suspension of Edaravone in Healthy Adults.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 10, p. 1174, doi. 10.1002/cpdd.925

By:

Shimizu, Hidetoshi;
Nishimura, Yukiko;
Shiide, Yoichi;
Matsuda, Hideaki;
Akimoto, Makoto;
Matsuda, Munetomo;
Nakamaru, Yoshinobu;
Kato, Yuichiro;
Kondo, Kazuoki

Publication type:

Article

A Randomized, Single‐Blind, Placebo‐Controlled, 3‐Way Crossover Study to Evaluate the Effect of Therapeutic and Supratherapeutic Doses of Edaravone on QT/QTc Interval in Healthy Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 1, p. 46, doi. 10.1002/cpdd.814

By:

Shimizu, Hidetoshi;
Inoue, Shinsuke;
Endo, Mai;
Nakamaru, Yoshinobu;
Yoshida, Kaori;
Natori, Tomoko;
Kakubari, Masae;
Akimoto, Makoto;
Kondo, Kazuoki

Publication type:

Article

Edaravone dexborneol attenuates oxidative stress in experimental subarachnoid hemorrhage via Keap1/Nrf2 signaling pathway.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1342226

By:

Kunyuan Zhu;
Shijun Bi;
Zechao Zhu;
Wenxu Zhang;
Xinyu Yang;
Jiashuo Li;
Guobiao Liang;
Chunyong Yu;
Pengyu Pan

Publication type:

Article

Ginkgolide injections in meglumine, combined with edaravone, significantly increases the efficacy in acute ischemic stroke: A meta-analysis.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2023.1236684

By:

Mingyuan Yan;
Jing Wu;
Le Wang;
Kaiyue Wang;
Lili Li;
Tianye Sun;
Han Zhang;
Mi Zhang;
Lin Zou;
Songyi Yang;
Jinmin Liu

Publication type:

Article

Edaravone Protects against Methylglyoxal-Induced Barrier Damage in Human Brain Endothelial Cells.

Published in:

PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0100152

By:

Tóth, Andrea E.;
Walter, Fruzsina R.;
Bocsik, Alexandra;
Sántha, Petra;
Veszelka, Szilvia;
Nagy, Lajos;
Puskás, László G.;
Couraud, Pierre-Olivier;
Takata, Fuyuko;
Dohgu, Shinya;
Kataoka, Yasufumi;
Deli, Mária A.

Publication type:

Article

Edaravone Protect against Retinal Damage in Streptozotocin-Induced Diabetic Mice.

Published in:

PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0099219

By:

Yuan, Dongqing;
Xu, Yidan;
Hang, Hui;
Liu, Xiaoyi;
Chen, Xi;
Xie, Ping;
Yuan, Songtao;
Zhang, Weiwei;
Lin, Xiaojun;
Liu, Qinghuai

Publication type:

Article

Synergy of Combined tPA-Edaravone Therapy in Experimental Thrombotic Stroke.

Published in:

PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0098807

By:

Sun, Yu-Yo;
Morozov, Yury M.;
Yang, Dianer;
Li, Yikun;
Dunn, R. Scott;
Rakic, Pasko;
Chan, Pak H.;
Abe, Koji;
Lindquist, Diana M.;
Kuan, Chia-Yi

Publication type:

Article

Edaravone Protected Human Brain Microvascular Endothelial Cells from Methylglyoxal-Induced Injury by Inhibiting AGEs/RAGE/Oxidative Stress.

Published in:

PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0076025

By:

Li, Wenlu;
Xu, Hongjiao;
Hu, Yangmin;
He, Ping;
Ni, Zhenzhen;
Xu, Huimin;
Zhang, Zhongmiao;
Dai, Haibin

Publication type:

Article

C−H Functionalization Reactions of 1‐Aryl‐5‐pyrazolones.

Published in:

European Journal of Organic Chemistry, 2022, v. 2022, n. 45, p. 1, doi. 10.1002/ejoc.202201111

By:

Purohit, Vishal B.;
Prajapati, Ronak V.;
Prajapati, Vaibhav D.;
Karad, Sharad C.;
Sapariya, Nirav H.;
Avalani, Jemin R.;
Raval, Dipak K.

Publication type:

Article

THE EFFECT OF EDARAVONE COMBINED WITH DL-3-N-BUTYLPHTHALIDE ON THE LEVELS OF TUMOR NECROSIS FACTOR-ALPHA, INTERLEUKIN-10, NEURON-SPECIFIC ENOLASE AND EFFECT IN PATIENTS WITH ACUTE CEREBRAL INFARCTION.

Published in:

Journal of Physiology & Pharmacology, 2022, v. 73, n. 3, p. 1, doi. 10.26402/jpp.2022.3.05

By:

SHEN, Q. Q.;
WANG, W.;
WU, H.;
TONG, X. W.

Publication type:

Article

Edaravone ameliorates depressive and anxiety-like behaviors via Sirt1/Nrf2/HO-1/Gpx4 pathway.

Published in:

2022

By:

Dang, Ruozhi;
Wang, Mingyang;
Li, Xinhui;
Wang, Haiyang;
Liu, Lanxiang;
Wu, Qingyuan;
Zhao, Jianting;
Ji, Ping;
Zhong, Lianmei;
Licinio, Julio;
Xie, Peng

Publication type:

journal article

New Hybrid Structures Based on Memanthine and Edaravone Molecules.

Published in:

Doklady Biochemistry & Biophysics, 2023, v. 512, n. 1, p. 284, doi. 10.1134/S1607672923700461

By:

Grigoriev, V. V.;
Shevtsova, E. F.;
Aksinenko, A. Yu.;
Veselov, I. M.;
Goreva, T. V.;
Gabrelyan, A. V.;
Bachurin, S. O.

Publication type:

Article

Clinical trials in amyotrophic lateral sclerosis: a systematic review and perspective.

Published in:

Brain Communications, 2021, v. 3, n. 4, p. 1, doi. 10.1093/braincomms/fcab242

By:

Wong, Charis;
Stavrou, Maria;
Elliott, Elizabeth;
Gregory, Jenna M.;
Leigh, Nigel;
Pinto, Ashwin A.;
Williams, Timothy L.;
Chataway, Jeremy;
Swingler, Robert;
Parmar, Mahesh K. B.;
Stallard, Nigel;
Weir, Christopher J.;
Parker, Richard A.;
Chaouch, Amina;
Hamdalla, Hisham;
Ealing, John;
Gorrie, George;
Morrison, Ian;
Duncan, Callum;
Connelly, Peter

Publication type:

Article

Edaravone-loaded poly(amino acid) nanogel inhibits ferroptosis for neuroprotection in cerebral ischemia injury.

Published in:

Asian Journal of Pharmaceutical Sciences, 2024, v. 19, n. 2, p. 1, doi. 10.1016/j.ajps.2024.100886

By:

Yunhan Zhang;
Zhulin Zou;
Shuang Liu;
Fangfang Chen;
Minglu Li;
Haoyang Zou;
Haiyan Liu;
Jianxun Ding

Publication type:

Article

Edaravone inhibits autophagy after neuronal oxygen-glucose deprivation/recovery injury.

Published in:

International Journal of Neuroscience, 2019, v. 129, n. 5, p. 501, doi. 10.1080/00207454.2018.1550399

By:

Yin, Jian;
Zhou, Zheng;
Chen, Jian;
Wang, Qian;
Tang, Pengyu;
Ding, Qirui;
Yin, Guoyong;
Gu, Jun;
Fan, Jin

Publication type:

Article

Edaravone's free radical scavenging mechanisms of neuroprotection against cerebral ischemia: review of the literature.

Published in:

International Journal of Neuroscience, 2015, v. 125, n. 8, p. 555, doi. 10.3109/00207454.2014.959121

By:

Ren, Yanxin;
Wei, Bing;
Song, Xirui;
An, Nan;
Zhou, Yiying;
Jin, Xinxin;
Zhang, Yuyang

Publication type:

Article

Edaravone attenuates neuronal apoptosis in hippocampus of rat traumatic brain injury model via activation of BDNF/TrkB signaling pathway.

Published in:

2021

By:

Yuexia Ding;
Wei Zhu;
Wei Kong;
Tuo Li;
Peng Zou;
Hongguang Chen;
Ding, Yuexia;
Zhu, Wei;
Kong, Wei;
Li, Tuo;
Zou, Peng;
Chen, Hongguang

Publication type:

journal article

Efficacy of a Combination of Nimodipine and Edaravone in the Treatment of Acute Cerebral Hemorrhage.

Published in:

Indian Journal of Pharmaceutical Sciences, 2020, v. 82, p. 63

By:

SUZHEN WANG;
XIAOQIN AN;
YUEHUA WANG;
ZHANG, J.;
QI, L.

Publication type:

Article

Cost-effectiveness of edaravone dexborneol versus dl-3-n-butylphthalide for the treatment of acute ischemic stroke: a Chinese health care perspective.

Published in:

BMC Public Health, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12889-024-17959-3

By:

Li, Jianchun;
Cao, Weihan;
Zhao, Fei;
Jin, Pengfei

Publication type:

Article

Bacterial toxicity of Acetaminophen and Edaravone, and their binary mixtures: experimental and predicted values using traditional and novel Van Laar-based models.

Published in:

Ecotoxicology, 2024, v. 33, n. 7, p. 722, doi. 10.1007/s10646-024-02772-w

By:

Álvarez-Escalante, Iván;
Martínez-Páramo, Sonia;
Irusta-Mata, Rubén

Publication type:

Article

Antidepressant-Like Effects of Edaravone and Minocycline: Investigation of Oxidative Stress, Neuroinflammation, Neurotrophic, and Apoptotic Pathways.

Published in:

Neurotoxicity Research, 2022, v. 40, n. 6, p. 1838, doi. 10.1007/s12640-022-00603-6

By:

Motafeghi, Farzaneh;
Bagheri, Abouzar;
Seyedabadi, Mohammad;
Shaki, Fatemeh;
Shokrzadeh, Mohammad

Publication type:

Article

Neuroprotection of Oral Edaravone on Middle Cerebral Artery Occlusion in Rats.

Published in:

Neurotoxicity Research, 2022, v. 40, n. 4, p. 995, doi. 10.1007/s12640-022-00520-8

By:

Zhao, Li-Qin;
Parikh, Ankit;
Xiong, Yun-Xia;
Ye, Qing-Yan;
Ying-Guo;
Zhou, Xin-Fu;
Luo, Hai-Yun

Publication type:

Article

Preclinical validation of a novel oral Edaravone formulation for treatment of frontotemporal dementia.

Published in:

Neurotoxicity Research, 2021, v. 39, n. 6, p. 1689, doi. 10.1007/s12640-021-00405-2

By:

Kelliny, Sally;
Xiong, Jing;
Bobrovskaya, Larisa;
Zhou, Xin-Fu

Publication type:

Article

Design, synthesis and biological evaluation of edaravone derivatives bearing the N-benzyl pyridinium moiety as multifunctional anti-Alzheimer's agents.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2020, v. 35, n. 1, p. 1596, doi. 10.1080/14756366.2020.1801673

By:

Zondagh, Luke S.;
Malan, Sarel F.;
Joubert, Jacques

Publication type:

Article

Edaravone: A Possible Treatment for Acute Lung Injury.

Published in:

International Journal of General Medicine, 2024, v. 17, p. 3975, doi. 10.2147/IJGM.S467891

By:

Huang, Ma;
Mo, Yalan;
Lei, Haiyun;
Chen, Miao

Publication type:

Article

Edaravone protects against hyperosmolarity-induced oxidative stress and apoptosis in primary human corneal epithelial cells.

Published in:

PLoS ONE, 2017, v. 12, n. 3, p. 1, doi. 10.1371/journal.pone.0174437

By:

Li, Yanwei;
Liu, Haifeng;
Zeng, Wei;
Wei, Jing

Publication type:

Article

Docetaxel-induced cognitive impairment in rats can be ameliorated by edaravone dexborneol: Evidence from the indicators of biological behavior and anisotropic fraction.

Published in:

Frontiers in Neuroscience, 2023, v. 17, p. 1, doi. 10.3389/fnins.2023.1167425

By:

Ping Liu;
Hai Liu;
Lijun Wei;
Xun Shi;
Wei Wang;
Shengxiang Yan;
Wenya Zhou;
Jiangong Zhang;
Suxia Han

Publication type:

Article

A Novel LC–MS-MS Method With an Effective Antioxidant for the Determination of Edaravone, a Free-Radical Scavenger in Dog Plasma and its Application to a Pharmacokinetic Study.

Published in:

Journal of Chromatographic Science, 2017, v. 55, n. 6, p. 595, doi. 10.1093/chromsci/bmx012

By:

Feng Shao;
Xiao-ling Hu;
Xin Liu;
Mang-ting Shan

Publication type:

Article

Meta-analysis of the effect of Xuesaitong combined with edaravone on hemorheological indexes in patients with acute cerebral infarction.

Published in:

Journal of Hainan Medical University, 2021, v. 27, n. 23, p. 39

By:

Ming-Yuan Yan;
Hai-Ruo Wang;
Hai-Yan Zhang;
Rui-Jia Liu;
Feng-Zhi Liu;
Meng-Xia Gao;
Dong-Rui Zhou;
Jing-Ling Chang;
Ling-Qun Zhu

Publication type:

Article

银杏二萜内酯葡胺联合依达拉奉右莰醇、丁苯酞注射液对超溶栓时间窗急性脑梗死的临床应用.

Published in:

Progress in Modern Biomedicine, 2024, v. 24, n. 20, p. 3926, doi. 10.13241/j.cnki.pmb.2024.20.033

By:

费娜;
李超生;
程力群;
殷晓菁;
刘丽;
金晶

Publication type:

Article

依达拉奉右莰醇联合丁苯酞治疗对老年大动脉粥样硬化型脑卒中患者血清 PTX3、lp-PLA2 以及 MES 的影响.

Published in:

Progress in Modern Biomedicine, 2023, v. 23, n. 12, p. 2392, doi. 10.13241/j.cnki.pmb.2023.12.036

By:

景燕;
王泽斌;
曾姗;
陆明佳;
仲婷;
李红燕

Publication type:

Article

麻醉诱导前给予依达拉奉与地塞米松联合 BIS 监测对胸腔镜下肺叶切除术后肺保护与术后恢复的影响.

Published in:

Progress in Modern Biomedicine, 2023, v. 23, n. 6, p. 1085, doi. 10.13241/j.cnki.pmb.2023.06.017

By:

陈鹏;
吕光;
赵宇浩;
蒋岩;
尹述洲

Publication type:

Article

杏芎氯化钠注射液联合依达拉奉对急性脑梗死患者神经功能、脑血流灌注及氧化应激水平的影响.

Published in:

Progress in Modern Biomedicine, 2021, v. 21, n. 7, p. 1374, doi. 10.13241/j.cnki.pmb.2021.07.038

By:

杨贤科;
钱浓;
彭先波;
潘兴;
马妮

Publication type:

Article

芪龙通络胶囊联合长春西汀对脑梗死患者神经功能、血管内皮功能及血液流变学的影响.

Published in:

Progress in Modern Biomedicine, 2020, v. 12, n. 24, p. 4747, doi. 10.13241/j.cnki.pmb.2020.24.033

By:

郝晨光;
雷晶;
马娟;
何丹;
卜国森

Publication type:

Article

阿替普酶联合依达拉奉治疗急性缺血性卒中的疗效及神经功能缺损与时间窗的关系研究.

Published in:

Progress in Modern Biomedicine, 2020, v. 20, n. 1, p. 172, doi. 10.13241/j.cnki.pmb.2020.01.038

By:

彭道勇;
王晓东;
王茂湘;
邓勇;
孙小鹏;
周中和

Publication type:

Article

依达拉奉联合红花黄色素对急性脑梗死患者神经功能、血脂水平及血液流变学的影响

Published in:

Progress in Modern Biomedicine, 2019, v. 19, n. 5, p. 919, doi. 10.13241/j.cnki.pmb.2019.05.028

By:

吴小英;
陈坊园;
张旭日;
岑运光;
李唐瑛

Publication type:

Article

依达拉奉联合克林澳对急性脑梗死患者血清MMP-3、MMP-9、TIMP-1、 EPCs的影响及疗效观察

Published in:

Progress in Modern Biomedicine, 2018, v. 18, n. 23, p. 4539, doi. 10.13241/j.cnki.pmb.2018.23.033

By:

董亚茹;
薛秀云;
张琳;
史利利;
党晓燕

Publication type:

Article