High-Temperature Synthesis of Amides from Alcohols or Aldehydes by Using Flow Chemistry.

Ambreen, Nida; Wirth, Thomas

An efficient conversion of aliphatic and aromatic alcohols or aldehydes into the corresponding primary amides was successfully achieved by using flow chemistry. Excellent yields were obtained in very short reaction times, and thus this method offers an efficient alternative to traditional methods for amide formation.

AMIDE synthesis; AROMATIC compound synthesis; ALDEHYDE synthesis; FLOW chemistry; MICROREACTORS

European Journal of Organic Chemistry, 2014, Vol 2014, Issue 34, p7590

1434-193X

Academic Journal

10.1002/ejoc.201403280