Works matching DE "DRUG repositioning"
Results: 1746
MAPK and STAT3 Inhibitors Modulate FoxP3 Expression and Regulatory T Cell Function.
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- European Journal of Immunology, 2025, v. 55, n. 2, p. 1, doi. 10.1002/eji.202451225
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Repurposing bosentan as an anticancer agent: EGFR/ERK/c‐Jun modulation inhibits NSCLC tumor growth.
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- Fundamental & Clinical Pharmacology, 2025, v. 39, n. 1, p. 1, doi. 10.1111/fcp.13052
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Fundamental and Clinical Pharmacology of drug repositioning.
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- Fundamental & Clinical Pharmacology, 2025, v. 39, n. 1, p. 1, doi. 10.1111/fcp.13046
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Repurposing of nervous system drugs for cancer treatment: recent advances, challenges, and future perspectives.
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- Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02067-4
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- Article
Glucocorticoid promotes metastasis of colorectal cancer via co‐regulation of glucocorticoid receptor and TET2.
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- International Journal of Cancer, 2025, v. 156, n. 8, p. 1572, doi. 10.1002/ijc.35285
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How many drugs are repositioned each year in Europe?
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- Journal of World Intellectual Property, 2025, v. 28, n. 1, p. 155, doi. 10.1111/jwip.12327
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Challenges, unmet needs and future directions – a critical evaluation of the clinical trial landscape in schizophrenia research.
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- Expert Review of Clinical Pharmacology, 2024, v. 17, n. 1, p. 11, doi. 10.1080/17512433.2023.2293996
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Multitargeted polypharmacotherapy for cancer treatment. theoretical concepts and proposals.
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- Expert Review of Anticancer Therapy, 2024, v. 24, n. 8, p. 665, doi. 10.1080/14737140.2024.2372336
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Population‐Based Validation Results From the Drug Repurposing for Effective Alzheimer's Medicines (DREAM) Study.
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- Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 4, p. 1039, doi. 10.1002/cpt.3583
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Exploring Drug Repurposing for Interstitial Cystitis/Bladder Pain Syndrome: Defining Novel Therapeutic Targets.
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- Neurourology & Urodynamics, 2025, v. 44, n. 2, p. 496, doi. 10.1002/nau.25651
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Unraveling the Role of Repurposed Drugs in the Treatment of Acne: Success so Far and the Road Ahead.
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- Drug Development Research, 2025, v. 86, n. 1, p. 1, doi. 10.1002/ddr.70057
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- Article
From old to new: Repurposed drugs in the battle towards curing sickle cell disease.
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- British Journal of Haematology, 2025, v. 206, n. 2, p. 795, doi. 10.1111/bjh.19912
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Drug repurposing and personalized treatment strategies for bipolar disorder using transcriptomics: an exploratory study.
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- Brazilian Journal of Psychiatry / Revista Brasileira de Psiquiatria, 2024, v. 46, p. 1, doi. 10.47626/1516-4446-2023-3441
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- Article
Repurposing hydrochlorothiazide (HCTZ) for colorectal cancer: a retrospective and single center study.
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- Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1449062
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- Article
Repurposing selective serotonin reuptake inhibitors for wound infection management: Expanding the scope of non‐antibiotic therapeutics.
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- Wound Repair & Regeneration, 2025, v. 33, n. 1, p. 1, doi. 10.1111/wrr.70006
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An in silico Drug Repurposing Study to Inhibit the Spike Protein of SARS-CoV2.
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- Momona Ethiopian Journal of Science, 2024, v. 16, n. 2, p. 347, doi. 10.4314/mejs.v16i2.11
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Research for a Common Thread: Insights into the Mechanisms of Six Potential Anticancer Agents.
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- Molecules, 2025, v. 30, n. 5, p. 1031, doi. 10.3390/molecules30051031
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- Article
Study on Drug Repurposing for ALS Treatment Using Pre-trained Knowledge Graph Embeddings: Methods and Findings.
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- Duzce University Journal of Science & Technology, 2025, v. 13, n. 1, p. 317, doi. 10.29130/dubited.1507832
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- Article
癌症精准治疗中的合成致死互作研究.
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- Chinese Journal of Bioinformatics, 2025, n. 1, p. 28, doi. 10.12113/202309007
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- Article
TTFields und CUSP9v3: Potenzial für verbesserte Glioblastomtherapien.
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- Kompass Onkologie, 2025, v. 12, n. 1, p. 12, doi. 10.1159/000544160
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- Article
Can Anticancer Drugs Be A Promising Candidate for The Treatment of Endometriosis?
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- Cell Journal (Yakhteh), 2024, v. 26, n. 10, p. 619, doi. 10.22074/cellj.2025.2037024.1635
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- Article
Repurposing pitavastatin and atorvastatin to overcome chemoresistance of metastatic colorectal cancer under high glucose conditions.
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- Cancer Cell International, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12935-025-03712-2
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Improving drug repositioning accuracy using non-negative matrix tri-factorization.
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- Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-91757-8
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- Article
Comparative evaluation of different treatment regimens of a tertiary care hospital -- A retrospective study for COVID-19 Patients.
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- European Journal of Cardiovascular Medicine, 2024, v. 14, n. 6, p. 572
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- Article
Meloxicam mitigated methylglyoxal-induced glycative stress in rats.
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- Iranian Journal of Basic Medical Sciences, 2025, v. 28, n. 5, p. 647, doi. 10.22038/ijbms.2025.83856.18143
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- Article
The clinically applied PARP inhibitor talazoparib ameliorates imiquimod-induced psoriasis in mice without reducing skin inflammation.
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- Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1519066
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iDOMO: identification of drug combinations via multi-set operations for treating diseases.
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- Briefings in Bioinformatics, 2025, v. 26, n. 1, p. 1, doi. 10.1093/bib/bbaf054
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Machine learning–enabled virtual screening indicates the anti-tuberculosis activity of aldoxorubicin and quarfloxin with verification by molecular docking, molecular dynamics simulations, and biological evaluations.
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- Briefings in Bioinformatics, 2025, v. 26, n. 1, p. 1, doi. 10.1093/bib/bbae696
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- Article
Heterogeneous graph contrastive learning with gradient balance for drug repositioning.
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- Briefings in Bioinformatics, 2025, v. 26, n. 1, p. 1, doi. 10.1093/bib/bbae650
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- Article
ANTICANCER ACTIVITY OF MELATONIN AND METFORMIN ALONE AND IN COMBINATION AGAINST MELANOMA AND BREAST CANCER CELLS.
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- Acta Poloniae Pharmaceutica, 2024, v. 81, n. 5, p. 767, doi. 10.32383/appdr/197350
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Comparative in vitro and in silico evaluation of the toxic effects of metformin and/or ascorbic acid, new treatment options in the treatment of Melasma.
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- Toxicology Research, 2025, v. 14, n. 1, p. 1, doi. 10.1093/toxres/tfaf025
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Repurposing of apoptotic inducer drugs against Mycobacterium tuberculosis.
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- Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-91096-8
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- Article
Mirvetuximab Soravtansine Induces Potent Cytotoxicity and Bystander Effect in Cisplatin-Resistant Germ Cell Tumor Cells.
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- Cells (2073-4409), 2025, v. 14, n. 4, p. 287, doi. 10.3390/cells14040287
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- Article
Phytoactive-Loaded Lipid Nanocarriers for Simvastatin Delivery: A Drug Repositioning Strategy Against Lung Cancer.
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- Pharmaceutics, 2025, v. 17, n. 2, p. 255, doi. 10.3390/pharmaceutics17020255
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- Article
Drug Repurposing of Voglibose, a Diabetes Medication for Skin Health.
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- Pharmaceuticals (14248247), 2025, v. 18, n. 2, p. 224, doi. 10.3390/ph18020224
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Prescribing the Future: The Role of Artificial Intelligence in Pharmacy.
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- Information (2078-2489), 2025, v. 16, n. 2, p. 131, doi. 10.3390/info16020131
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- Article
Storage and Query of Drug Knowledge Graphs Using Distributed Graph Databases: A Case Study.
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- Bioengineering (Basel), 2025, v. 12, n. 2, p. 115, doi. 10.3390/bioengineering12020115
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- Article
Repurposing COVID-19 Compounds (via MMV COVID Box): Almitrine and Bortezomib Induce Programmed Cell Death in Trypanosoma cruzi.
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- Pathogens, 2025, v. 14, n. 2, p. 127, doi. 10.3390/pathogens14020127
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- Article
Evaluation of Amlodipine and Imipramine Efficacy to Treat Galleria mellonella Infection by Biofilm-Producing and Antimicrobial-Resistant Staphylococcus aureus.
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- Antibiotics (2079-6382), 2025, v. 14, n. 2, p. 183, doi. 10.3390/antibiotics14020183
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- Article
Antimicrobial and Antibiofilm Activity of Auranofin and Its Two Derivatives Bearing Naproxen and Acetylcysteine as Ligands Against Staphylococci †.
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- Antibiotics (2079-6382), 2025, v. 14, n. 2, p. 118, doi. 10.3390/antibiotics14020118
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KGRDR: a deep learning model based on knowledge graph and graph regularized integration for drug repositioning.
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- Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1525029
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- Article
Proteomic analysis reveals chromatin remodeling as a potential therapeutical target in neuroblastoma.
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- Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06298-5
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- Article
Evaluation of the Potency of Repurposed Antiretrovirals in HBV Therapy: A Narrative Investigation of the Traditional Medicine Alternatives.
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- International Journal of Molecular Sciences, 2025, v. 26, n. 4, p. 1523, doi. 10.3390/ijms26041523
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Combining Sulfonylureas with Anticancer Drugs: Evidence of Synergistic Efficacy with Doxorubicin In Vitro and In Vivo.
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- International Journal of Molecular Sciences, 2025, v. 26, n. 4, p. 1429, doi. 10.3390/ijms26041429
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- Article
Rifampicin Repurposing Reveals Anti-Melanogenic Activity in B16F10 Melanoma Cells.
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- Molecules, 2025, v. 30, n. 4, p. 900, doi. 10.3390/molecules30040900
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- Article
Risk factors associated with the onset of lomustine‐induced neutropenia in tumour‐bearing dogs.
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- Veterinary & Comparative Oncology, 2022, v. 20, n. 3, p. 577, doi. 10.1111/vco.12809
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- Article
Non‐Medical Applications of Inorganic Medicines. A Switch Based on Mechanistic Knowledge.
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- Chemistry - A European Journal, 2024, v. 30, n. 60, p. 1, doi. 10.1002/chem.202402647
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- Article
Near Infrared Light‐Triggered Photocatalytic Decaging for Remote‐Controlled Spatiotemporal Activation in Living Mice.
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- Angewandte Chemie, 2023, v. 135, n. 48, p. 1, doi. 10.1002/ange.202310920
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- Article
Drug Repurposing by Siderophore Conjugation: Synthesis and Biological Evaluation of Siderophore‐Methotrexate Conjugates as Antibiotics.
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- Angewandte Chemie, 2022, v. 134, n. 36, p. 1, doi. 10.1002/ange.202204139
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- Article
Repurposing an Antiviral Drug against SARS‐CoV‐2 Main Protease.
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- Angewandte Chemie, 2021, v. 133, n. 44, p. 23684, doi. 10.1002/ange.202107481
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- Article