Results: 27
New Ester‐Containing Azole Derivatives With Potent Anti‐Candida Effects: Synthesis, Antifungal Susceptibility, Cytotoxicity, and Molecular Modeling Studies.
- Published in:
- Drug Development Research, 2024, v. 85, n. 7, p. 1, doi. 10.1002/ddr.70021
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- Article
Ambroxol Improves Amyloidogenic, NF‐κB, and Nrf2 Pathways in a Scopolamine‐Induced Cognitive Impairment Rat Model of Alzheimer's Disease.
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- Drug Development Research, 2024, v. 85, n. 7, p. 1, doi. 10.1002/ddr.70017
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- Article
Discovery of Novel SIRT3 Inhibitors for the Cancer Differentiation Therapy by Structural Modification.
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- Drug Development Research, 2024, v. 85, n. 7, p. 1, doi. 10.1002/ddr.70016
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- Article
KLF2 Inhibits Ferroptosis and Improves Mitochondrial Dysfunction in Chondrocyte Through SIRT1/GPX4 Signaling to Improve Osteoarthritis.
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- Drug Development Research, 2024, v. 85, n. 7, p. 1, doi. 10.1002/ddr.70015
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- Article
The Role of Fatty Acid Metabolism, the Related Potential Biomarkers, and Targeted Therapeutic Strategies in Gastrointestinal Cancers.
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- Drug Development Research, 2024, v. 85, n. 7, p. 1, doi. 10.1002/ddr.70014
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- Publication type:
- Article
PARP7i Clinical Candidate RBN‐2397 Exerts Antiviral Activity by Modulating Interferon‐β Associated Innate Immune Response in Macrophages.
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- Drug Development Research, 2024, v. 85, n. 7, p. 1, doi. 10.1002/ddr.70013
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- Article
Agmatine: An Emerging Approach for Neuroprotection in Recurrent Ischemic Stroke Events in a Murine Model.
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- Drug Development Research, 2024, v. 85, n. 7, p. 1, doi. 10.1002/ddr.70012
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- Publication type:
- Article
RNA sequencing comparing centenarian and middle‐aged women lymphoblastoid cell lines identifies age‐related dysregulated expression of genes encoding selenoproteins, heat shock proteins, CD99, and BID.
- Published in:
- Drug Development Research, 2024, v. 85, n. 7, p. 1, doi. 10.1002/ddr.70011
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- Article
MLLT3 knockdown suppresses proliferation and cell mobility in human lung adenocarcinoma.
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- Drug Development Research, 2024, v. 85, n. 7, p. 1, doi. 10.1002/ddr.70010
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- Article
Molecular docking, DFT and antiproliferative properties of 4‐(3,4‐dimethoxyphenyl)−3‐(4‐methoxyphenyl)−1‐phenyl‐1H‐pyrazolo[3,4‐b]pyridine as potent anticancer agent with CDK2 and PIM1 inhibition potency
- Published in:
- Drug Development Research, 2024, v. 85, n. 7, p. 1, doi. 10.1002/ddr.70009
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- Article
Design, synthesis, and evaluation of novel Indole‐Based small molecules as sirtuin inhibitors with anticancer activities.
- Published in:
- Drug Development Research, 2024, v. 85, n. 7, p. 1, doi. 10.1002/ddr.70008
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- Article
New S‐substituted‐3‐phenyltetrahydrobenzo[4,5]thieno[2,3‐d]pyrimidin‐4(3H)‐one scaffold with promising anticancer activity profile through the regulation and inhibition of mutated B‐RAF signaling pathway.
- Published in:
- Drug Development Research, 2024, v. 85, n. 7, p. 1, doi. 10.1002/ddr.70007
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- Publication type:
- Article
Downregulation of short‐stature homeobox protein 2 suppresses gastric cancer cell growth and stemness in vitro and in vivo via inactivating wnt/β‐catenin signaling.
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- Drug Development Research, 2024, v. 85, n. 7, p. 1, doi. 10.1002/ddr.70006
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- Publication type:
- Article
The role and advance of ubiquitination and deubiquitination in depression pathogenesis and treatment.
- Published in:
- Drug Development Research, 2024, v. 85, n. 7, p. 1, doi. 10.1002/ddr.70005
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- Publication type:
- Article
Knockdown of ENO1 promotes autophagy dependent‐ferroptosis and suppresses glycolysis in breast cancer cells via the regulation of CST1.
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- Drug Development Research, 2024, v. 85, n. 7, p. 1, doi. 10.1002/ddr.70004
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- Publication type:
- Article
RecQ protein‐like 4 drives cisplatin chemosensitivity of cervical cancer cells by modulating annexin A2.
- Published in:
- Drug Development Research, 2024, v. 85, n. 7, p. 1, doi. 10.1002/ddr.70003
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- Publication type:
- Article
Tropisetron attenuates high glucose‐induced oxidative stress and inflammation in ARPE‐19 cells in vitro via regulating SIRT1/ROCK1 signaling.
- Published in:
- Drug Development Research, 2024, v. 85, n. 7, p. 1, doi. 10.1002/ddr.70002
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- Publication type:
- Article
Role of BIX01294 in the intracranial inhibition of H3K9 methylation lessens neuronal loss in vascular dementia model.
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- Drug Development Research, 2024, v. 85, n. 7, p. 1, doi. 10.1002/ddr.70001
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- Publication type:
- Article
Trifolirhizin targets PTK6 to induce autophagy and exerts antitumor effects in nasopharyngeal carcinoma.
- Published in:
- Drug Development Research, 2024, v. 85, n. 7, p. 1, doi. 10.1002/ddr.70000
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- Publication type:
- Article
<sup>89</sup>Zr‐Labeled DFO@Durvalumab‐HSA nanoparticles: In vitro potential for triple‐negative breast cancer.
- Published in:
- Drug Development Research, 2024, v. 85, n. 7, p. 1, doi. 10.1002/ddr.22266
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- Publication type:
- Article
Sm(Ⅲ), Gd(Ⅲ), and Eu(Ⅲ) complexes with 8‐hydroxyquinoline derivatives as potential anticancer agents via inhibiting cell proliferation, blocking cell cycle, and inducing apoptosis in NCI‐H460 cells.
- Published in:
- Drug Development Research, 2024, v. 85, n. 7, p. 1, doi. 10.1002/ddr.22265
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- Publication type:
- Article
Synthesis, anticancer activity and mechanism of action of Fe(III) complexes.
- Published in:
- Drug Development Research, 2024, v. 85, n. 7, p. 1, doi. 10.1002/ddr.22264
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- Publication type:
- Article
Epigenetic mechanism of EZH2‐mediated histone methylation modification in regulating ferroptosis of alveolar epithelial cells in sepsis‐induced acute lung injury.
- Published in:
- Drug Development Research, 2024, v. 85, n. 7, p. 1, doi. 10.1002/ddr.22263
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- Article
Issue Information.
- Published in:
- Drug Development Research, 2024, v. 85, n. 7, p. 1, doi. 10.1002/ddr.22262
- Publication type:
- Article
Targeted therapies for Glioblastoma multiforme (GBM): State‐of‐the‐art and future prospects.
- Published in:
- Drug Development Research, 2024, v. 85, n. 7, p. 1, doi. 10.1002/ddr.22261
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- Publication type:
- Article
m6A‐activated BACH1 exacerbates ferroptosis by epigenetic suppression HSPB1 in severe acute pancreatitis.
- Published in:
- Drug Development Research, 2024, v. 85, n. 7, p. 1, doi. 10.1002/ddr.22256
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- Publication type:
- Article
EGCG enhances antitumor effect of apatinib in nonsmall cell lung cancer by targeting VEGF signaling to inhibit glycolysis.
- Published in:
- Drug Development Research, 2024, v. 85, n. 7, p. 1, doi. 10.1002/ddr.22239
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- Publication type:
- Article